2021
Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty
Cabrejo R, Lacadie C, Sun A, Chuang C, Yang J, Brooks E, Beckett J, Eilbott J, Gabrick K, Steinbacher D, Duncan C, DiLuna M, Alperovich M, Pelphrey K, Ventola P, Constable T, Persing JA. Functional Network Development in Sagittal Craniosynostosis Treated With Whole Vault Cranioplasty. Journal Of Craniofacial Surgery 2021, 32: 1721-1726. PMID: 33534301, DOI: 10.1097/scs.0000000000007505.Peer-Reviewed Original ResearchConceptsWhole-vault cranioplastySagittal craniosynostosisFunctional MRICase-control study designFunctional MRI scansControl study designAbnormal network connectionsFunctional network developmentNeurological changesIndividual patientsMRI scansFunctional brain networksCerebral networksFunctional connectivityVisual networkConnectivity changesPatientsStudy designSurgeryAdolescent controlsBrain networksCraniosynostosisWVC groupInfantsExecutive functionLong-Term Neurocognitive Outcomes in Sagittal Synostosis: The Impact of Reoperation.
Chuang C, Chaunzwa TL, Wu R, Singh A, Patel A, Yang JF, Hashim PW, Travieso R, Terner JS, Mayes LC, Duncan CC, Jane JA, Lin KY, Bridgett DJ, Persing JA. Long-Term Neurocognitive Outcomes in Sagittal Synostosis: The Impact of Reoperation. Journal Of Craniofacial Surgery 2021, 32: 58-61. PMID: 33394632, DOI: 10.1097/scs.0000000000006909.Peer-Reviewed Original ResearchConceptsEarly surgery patientsImpact of reoperationSurgery patientsNonsyndromic sagittal craniosynostosisNeurocognitive outcomesWhole-vault cranioplastyReoperation rateSagittal craniosynostosisVisuomotor integrationComprehensive neurocognitive testingLate surgery patientsWorse neurocognitive outcomesTerm Neurocognitive OutcomesStandardized neuropsychological testingLife surgeryUnderwent reoperationEarly surgeryLate surgerySchool-aged childrenReoperationOutcome measuresNeuropsychological testingPatientsNeurocognitive testingNeurocognitive function
2020
Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus
Jin SC, Dong W, Kundishora AJ, Panchagnula S, Moreno-De-Luca A, Furey CG, Allocco AA, Walker RL, Nelson-Williams C, Smith H, Dunbar A, Conine S, Lu Q, Zeng X, Sierant MC, Knight JR, Sullivan W, Duy PQ, DeSpenza T, Reeves BC, Karimy JK, Marlier A, Castaldi C, Tikhonova IR, Li B, Peña HP, Broach JR, Kabachelor EM, Ssenyonga P, Hehnly C, Ge L, Keren B, Timberlake AT, Goto J, Mangano FT, Johnston JM, Butler WE, Warf BC, Smith ER, Schiff SJ, Limbrick DD, Heuer G, Jackson EM, Iskandar BJ, Mane S, Haider S, Guclu B, Bayri Y, Sahin Y, Duncan CC, Apuzzo MLJ, DiLuna ML, Hoffman EJ, Sestan N, Ment LR, Alper SL, Bilguvar K, Geschwind DH, Günel M, Lifton RP, Kahle KT. Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus. Nature Medicine 2020, 26: 1754-1765. PMID: 33077954, PMCID: PMC7871900, DOI: 10.1038/s41591-020-1090-2.Peer-Reviewed Original ResearchConceptsCongenital hydrocephalusPoor neurodevelopmental outcomesPost-surgical patientsCerebrospinal fluid accumulationNeural stem cell biologyGenetic disruptionWhole-exome sequencingPrimary pathomechanismEarly brain developmentNeurodevelopmental outcomesHigh morbidityCSF diversionMutation burdenFluid accumulationBrain ventriclesCH casesBrain developmentDe novo mutationsPatientsExome sequencingCSF dynamicsDisease mechanismsHydrocephalusNovo mutationsCell types
1983
Evaluation of Level of Consciousness by the Glasgow Coma Scale in Children with Reye's Syndrome
Duncan C, Ment L, Shaywitz B. Evaluation of Level of Consciousness by the Glasgow Coma Scale in Children with Reye's Syndrome. Neurosurgery 1983, 13: 650-653. PMID: 6657017, DOI: 10.1227/00006123-198312000-00005.Peer-Reviewed Original ResearchConceptsGlasgow Coma ScaleComa ScaleReye's syndromeProgressive central nervous system diseaseCentral nervous system diseaseNervous system diseasesIntracranial pressure monitoringLevel of consciousnessSuch patientsHead traumaPoor prognosisElevated ICPRapid progressionSystem diseasesPressure monitoringSyndromePatientsEvaluation of levelsEarly indicatorDiseasePrognosisLevelsPhysiciansTraumaProgressionEvaluation of Level of Consciousness by the Glasgow Coma Scale in Children with Reye's Syndrome.
Duncan C, Ment L, Shaywitz B. Evaluation of Level of Consciousness by the Glasgow Coma Scale in Children with Reye's Syndrome. Neurosurgery 1983, 13: 650. DOI: 10.1097/00006123-198312000-00005.Peer-Reviewed Original ResearchGlasgow Coma ScaleLevel of consciousnessComa ScaleReye's syndromeProgressive central nervous system diseaseCentral nervous system diseaseNervous system diseasesIntracranial pressure monitoringSuch patientsHead traumaPoor prognosisElevated ICPRapid progressionSurgeon evaluationSystem diseasesPressure monitoringSyndromePatientsEarly indicatorDiseasePrognosisLevelsPhysiciansTraumaProgressionThe diagnosis of fetal hydrocephalus
Chervenak F, Berkowitz R, Romero R, Tortora M, Mayden K, Duncan C, Mahoney M, Hobbins J. The diagnosis of fetal hydrocephalus. American Journal Of Obstetrics And Gynecology 1983, 147: 703-716. PMID: 6685439, DOI: 10.1016/0002-9378(83)90456-8.Peer-Reviewed Original Research
1981
Alterations in cerebral blood flow in preterm infants with intraventricular hemorrhage.
Ment L, Ehrenkranz R, Lange R, Rothstein P, Duncan C. Alterations in cerebral blood flow in preterm infants with intraventricular hemorrhage. Pediatrics 1981, 68: 763-9. PMID: 7322711, DOI: 10.1542/peds.68.6.763.Peer-Reviewed Original ResearchConceptsWeeks postconceptual ageGerminal matrix hemorrhageIntraventricular hemorrhageIVH groupPreterm infantsPostconceptual ageCerebral blood flow determinationsCerebral blood flowComputed tomography scanGroups of infantsBlood flow determinationsNonhemorrhage patientsIVH patientsAutopsy findingsTomography scanCT scanBlood flowHemorrhageHemispheric ratioInfantsMean differencePatientsLower mean valuesInterhemispheric ratioAgeComputed tomography in the diagnosis of Canavan's disease
Rushton A, Shaywitz B, Duncan C, Geehr R, Manuelidis E. Computed tomography in the diagnosis of Canavan's disease. Annals Of Neurology 1981, 10: 57-60. PMID: 7271233, DOI: 10.1002/ana.410100112.Peer-Reviewed Original ResearchConceptsBrain biopsyCanavan diseaseCT scanComputed tomographyWhite matter attenuationNormal neurological examinationDiagnostic brain biopsySubsequent developmental delayWhite matter disordersNeurological examinationCerebral hemispheresAlexander diseaseDevelopmental delayDiseaseYoung childrenBiopsyDisordersTomographyScansSymmetrical decreasePatientsAdrenoleukodystrophyDiagnosisMacrocephalyA Scale for the Assessment of Neonatal Neurologic Status
Duncan C, Ment L, Smith B, Ehrenkranz R. A Scale for the Assessment of Neonatal Neurologic Status. Child's Brain 1981, 8: 299-306. PMID: 7261694, DOI: 10.1159/000119993.Peer-Reviewed Original Research
1980
Evaluation of Complicated Migraine in Childhood
Ment L, Duncan C, Parcells P, Collins W. Evaluation of Complicated Migraine in Childhood. Child's Brain 1980, 7: 261-266. PMID: 7471914, DOI: 10.1159/000119953.Peer-Reviewed Original ResearchConceptsComplicated migraineCerebral blood flow determinationsPersistent neurologic sequelaeBlood flow determinationsNeurologic sequelaeAcute onsetNeurologic deficitsCerebral arteriogramsFamily historySymptom complexMigraineChildhoodFlow determinationSequelaeArteriogramsHemicraniumPatientsAbnormalities