2023
Chronic respiratory symptoms following deployment-related occupational and environmental exposures among US veterans
Garshick E, Redlich C, Korpak A, Timmons A, Smith N, Nakayama K, Baird C, Ciminera P, Kheradmand F, Fan V, Hart J, Koutrakis P, Kuschner W, Ioachimescu O, Jerrett M, Montgrain P, Proctor S, Wan E, Wendt C, Wongtrakool C, Blanc P. Chronic respiratory symptoms following deployment-related occupational and environmental exposures among US veterans. Occupational And Environmental Medicine 2023, 81: 59-65. PMID: 37968126, PMCID: PMC10872566, DOI: 10.1136/oemed-2023-109146.Peer-Reviewed Original ResearchChronic respiratory symptomsRespiratory symptomsUS veteransPit smokeChronic bronchitisInhalational exposureInterviewer-administered questionnaireCross-sectional studySmoke exposureHeavy exposureVGDFDeployment exposuresSymptomsExposure itemsItem reductionEnvironmental exposuresScore incrementsWheezeBronchitisExposure frequencyVeteransExposureLogit linkMonthsSmoke
2022
Assessment of personal inhalation and skin exposures to polymeric methylene diphenyl diisocyanate during polyurethane fabric coating
Harari H, Bello D, Woskie S, Redlich CA. Assessment of personal inhalation and skin exposures to polymeric methylene diphenyl diisocyanate during polyurethane fabric coating. Toxicology And Industrial Health 2022, 38: 622-635. PMID: 35694796, DOI: 10.1177/07482337221107243.Peer-Reviewed Original ResearchConceptsSkin exposurePersonal inhalationOccupational asthmaHypersensitivity pneumonitisContact dermatitisInitial sensitizationWork exposureArea air samplesInhalation exposureOccupational limitsLiquid chromatography-tandem mass spectrometryHealth effects studiesHealth effectsPersonal airborne samplesGeometric meanChromatography-tandem mass spectrometryExposure characterizationInhalationExposureFuture studiesGreater exposureAirborne levelsSubstantial variabilityProtective measuresGeometric standard deviation
2021
Assessment of the Workplace
Doekes G, Raulf M, Heederik D, Redlich C, Tarlo S, Malo J. Assessment of the Workplace. 2021, 67-80. DOI: 10.1201/9781003000624-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsJob-exposure matrixExposure assessment strategiesExposure assessmentDispersion techniqueRespiratory tract exposureWork-related asthmaOccupational health studiesBiological methodsAllergic sensitizationRespiratory tractCharacterization of exposureHealth StudyIrritant agentsAirborne exposureChemicalsSkin contactDermal exposureHealth risk assessmentExposure levelsImportant routeAirborne agentsExposureFloor dustBiological agentsParticlesSymptomatic Responses to Low‐Level Occupational and Environmental Exposures
Linde B, Redlich C. Symptomatic Responses to Low‐Level Occupational and Environmental Exposures. 2021, 1-14. DOI: 10.1002/0471435139.hyg013.pub3.ChaptersLow-level exposureSymptomatic responseManagement of symptomsMultiple chemical sensitivityIdiopathic environmental intoleranceLikely multifactorialMedical evaluationPatient's conditionChemical intoleranceGasoline fumesEnvironmental intoleranceDiagnostic termsSymptomsEnvironmental exposuresPerfumed productsWork accommodationsNew carpetingExposureIntolerancePsychological pathwaysChemical sensitivityResponsePathogenesisMultifactorialDiagnosis
2020
Master Clinician and Public Health Practitioner Selected Occupational and Environmental Pulmonary Cases
James E, Linde B, Redlich CA. Master Clinician and Public Health Practitioner Selected Occupational and Environmental Pulmonary Cases. Clinics In Chest Medicine 2020, 41: 567-580. PMID: 33153680, DOI: 10.1016/j.ccm.2020.08.019.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRespiratory diseasePatient's respiratory diseaseMost lung diseasesClinical decision makingPublic health practitionersExposure-related diseasesRelevance of exposureLung diseasePulmonary casesPublic health factorsHigh indexEnvironmental contributing factorsClinical practiceHealth factorsHealth practitionersDiseaseEnvironmental exposuresExposure historyClinical skillsCliniciansMaster cliniciansContributing factorExposurePatientsAppropriate work
2017
Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry
Collins JJ, Anteau S, Conner PR, Cassidy LD, Doney B, Wang ML, Kurth L, Carson M, Molenaar D, Redlich CA, Storey E. Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry. Journal Of Occupational And Environmental Medicine 2017, 59: s22-s27. PMID: 29200135, PMCID: PMC5763544, DOI: 10.1097/jom.0000000000000890.Peer-Reviewed Original Research
2016
Development of an Interception Glove Sampler for Skin Exposures to Aromatic Isocyanates
Harari H, Bello D, Woskie S, Redlich C. Development of an Interception Glove Sampler for Skin Exposures to Aromatic Isocyanates. Annals Of Work Exposures And Health 2016, 60: 1092-1103. PMID: 27694341, DOI: 10.1093/annhyg/mew052.Peer-Reviewed Original Research
2015
Longitudinal assessment of lung function decline in the occupational setting
Redlich CA, Tarlo SM. Longitudinal assessment of lung function decline in the occupational setting. Current Opinion In Allergy And Clinical Immunology 2015, 15: 145-149. PMID: 25961387, DOI: 10.1097/aci.0000000000000153.Peer-Reviewed Original ResearchConceptsLongitudinal lung functionLung functionLongitudinal spirometryMedical surveillanceFlavorings-related lung diseaseHazardous work exposuresLung function declineOccupational respiratory diseasesRecent longitudinal studiesFunction declineEarly diseaseLung diseaseOccupational exposureRespiratory diseaseWork exposureSpirometryPreventive interventionsLongitudinal assessmentFurther evaluationOccupational settingsDiseaseLongitudinal studyCliniciansExposureRecent studiesIsocyanates and Human Health
Lockey JE, Redlich CA, Streicher R, Pfahles-Hutchens A, Hakkinen P, Ellison GL, Harber P, Utell M, Holland J, Comai A, White M. Isocyanates and Human Health. Journal Of Occupational And Environmental Medicine 2015, 57: 44-51. PMID: 25563538, PMCID: PMC4286799, DOI: 10.1097/jom.0000000000000278.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOccupational health surveillanceHuman cancer riskRespiratory epidemiologyCancer riskConsensus conferenceAnimal modelsResearch prioritiesHealth professionalsHealth surveillancePreconference surveyEnvironmental exposuresWorkers' healthHealthConsumer exposureHuman healthKnowledge gapsExposureRepresentatives of consumersPoster presentationsEpidemiologyDiseaseBiomarkers
2014
Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: Initial one‐year follow‐up
Gui W, Wisnewski AV, Neamtiu I, Gurzau E, Sparer JA, Stowe MH, Liu J, Slade MD, Rusu OA, Redlich CA. Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: Initial one‐year follow‐up. American Journal Of Industrial Medicine 2014, 57: 1207-1215. PMID: 25266741, PMCID: PMC4198484, DOI: 10.1002/ajim.22385.Peer-Reviewed Original ResearchMeSH KeywordsAdultAir Pollutants, OccupationalAirway ObstructionAsthma, OccupationalFemaleFollow-Up StudiesForced Expiratory VolumeHumansImmunoglobulin EImmunoglobulin GLost to Follow-UpMaleMiddle AgedOccupational ExposurePolyurethanesPrevalenceProspective StudiesTime FactorsToluene 2,4-DiisocyanateVital CapacityYoung AdultConceptsAsthma symptomsIsocyanate asthmaInception cohort studyHealth effectsCurrent asthma symptomsTDI levelsFirst yearFurther longitudinal evaluationAirflow obstructionCohort studyInception cohortOccupational asthmaTDI exposureRespiratory healthSkin exposureLongitudinal evaluationAsthmaOne-yearPersonal samplingSymptomsRiskExposureFindingsFEV1Spirometry
2012
Transferability of Aliphatic Isocyanates from Recently Applied Paints to the Skin of Auto Body Shop Workers
De Vries TT, Bello D, Stowe MH, Harari H, Slade MD, Redlich CA. Transferability of Aliphatic Isocyanates from Recently Applied Paints to the Skin of Auto Body Shop Workers. Journal Of Occupational And Environmental Hygiene 2012, 9: 699-711. PMID: 23067057, DOI: 10.1080/15459624.2012.728893.Peer-Reviewed Original ResearchConceptsSkin exposureSkin samplesAuto body shop workersOccupational asthmaIsocyanate asthmaCommon causeSkin wipesGreater riskSkin contactPotent sensitizerInitial sampling timeShop workersPositive samplesAsthmaAuto body shopsHigh-performance liquid chromatographyExposureCross-linking chemicalsRiskGeometric meanLiquid chromatographyPrimary prevention: exposure reduction, skin exposure and respiratory protection
Heederik D, Henneberger PK, Redlich CA. Primary prevention: exposure reduction, skin exposure and respiratory protection. European Respiratory Review 2012, 21: 112-124. PMID: 22654083, PMCID: PMC9487304, DOI: 10.1183/09059180.00005111.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOccupational asthmaPrimary preventionSkin exposureLiterature searchExposure reductionSystematic literature searchNatural rubber latex glovesEffectiveness of respiratorsOccupational exposurePrimary preventive approachAsthmaExposure eliminationWork exposureWorkplace exposuresMedical literatureLatex glovesFuture interventionsPreventive approachPreventionRespiratory protectionExposureInterventionWeak evidenceEvidenceBest optionSkin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms
Arrandale V, Meijster T, Pronk A, Doekes G, Redlich CA, Holness DL, Heederik D. Skin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms. International Archives Of Occupational And Environmental Health 2012, 86: 167-175. PMID: 22411214, PMCID: PMC3555349, DOI: 10.1007/s00420-012-0760-x.Peer-Reviewed Original ResearchConceptsAuto body shop workersExposure-response relationshipRespiratory symptomsSkin symptomsItchy skinShop workersBakery workersPossible exposure-response relationshipSignificant exposure-response associationsExposure-response associationsRespiratory outcomesMean ageDry skinSkin exposureSymptomsAverage exposureStatistical significanceWheat allergensSkinExposureAssociationPrevious studiesResultsDataMethodsDataWorkers
2010
Automobile Maintenance, Repair and Refinishing
Stowe M, Redlich C. Automobile Maintenance, Repair and Refinishing. 2010, 203-210. DOI: 10.1002/9780470710425.ch15.ChaptersWork-exacerbated asthma
Henneberger P, Redlich C. Work-exacerbated asthma. Progress In Inflammation Research 2010, 89-100. DOI: 10.1007/978-3-7643-8556-9_6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsWork-exacerbated asthmaExacerbation of asthmaStandard medical managementSubstantial adverse outcomesNon-industrial workplacesConcurrent asthmaOccupational asthmaMedical managementAdverse outcomesCommon conditionAsthmaWork exposureMultiple factorsExposureExacerbationAllergensCliniciansPrevalenceIrritants
2008
Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: III. A Personal Exposure Algorithm
Liu Y, Stowe MH, Bello D, Sparer J, Gore RJ, Cullen MR, Redlich CA, Woskie SR. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: III. A Personal Exposure Algorithm. Annals Of Work Exposures And Health 2008, 53: 33-40. PMID: 19011126, PMCID: PMC2638551, DOI: 10.1093/annhyg/men070.Peer-Reviewed Original ResearchConceptsPersonal protective equipmentSkin exposureExposure metricsAuto body shop workersExposure indexUse of PPEExposure-response relationshipJob title categoriesAuto Body RepairIsocyanate asthmaExposure algorithmSemiquantitative algorithmSkin areasProtective equipmentSuch exposureExposure dataSpearman correlationShop workersExposure indicatorsOffice workersPositive Spearman correlationAuto body shopsExposureTask-based dataWork diariesSkin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: II. A Quantitative Assessment
Bello D, Redlich CA, Stowe MH, Sparer J, Woskie SR, Streicher RP, Hosgood HD, Liu Y. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: II. A Quantitative Assessment. Annals Of Work Exposures And Health 2008, 52: 117-124. PMID: 18209009, DOI: 10.1093/annhyg/mem066.Peer-Reviewed Original ResearchConceptsSkin exposureUnprotected skinAuto body shop workersAuto Body RepairRespiratory exposureSkin areasExposure dataShop workersSkin samplingSkinExposureWipe samplesUnpaired samplesHigh concentrationsPPEGm loadYale studyHigh levelsBody repairAsthmaMajor contributorLevelsQuantitative assessmentForearmSensitization
2007
Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: A Qualitative Assessment
LIU Y, BELLO D, SPARER JA, STOWE MH, GORE RJ, WOSKIE SR, CULLEN MR, REDLICH CA. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: A Qualitative Assessment. Annals Of Work Exposures And Health 2007, 51: 429-439. PMID: 17602207, DOI: 10.1093/annhyg/mem021.Peer-Reviewed Original ResearchConceptsAuto body shop workersSkin exposureHigh-performance liquid chromatographyShop workersHigher positive rateAuto Body RepairPositive surface samplesPositive sample rateEpidemiologic studiesUnprotected skinRespiratory exposurePercent of samplesSensitive high-performance liquid chromatographyLatex glovesScale 0Exposure dataExposure determinantsSkin samplesQuantitative high-performance liquid chromatographyNational InstituteOccupational SafetyAuto body shopsExposureMajor determinantPositive rate
2006
Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma
Ye YM, Kim CW, Kim HR, Kim HM, Suh CH, Nahm DH, Park HS, Redlich CA, Wisnewski AV. Biophysical determinants of toluene diisocyanate antigenicity associated with exposure and asthma. Journal Of Allergy And Clinical Immunology 2006, 118: 885-891. PMID: 17030242, DOI: 10.1016/j.jaci.2006.06.026.Peer-Reviewed Original ResearchRespiratory Protection from Isocyanate Exposure in the Autobody Repair and Refinishing Industry
Liu Y, Stowe MH, Bello D, Woskie SR, Sparer J, Gore R, Youngs F, Cullen MR, Redlich CA. Respiratory Protection from Isocyanate Exposure in the Autobody Repair and Refinishing Industry. Journal Of Occupational And Environmental Hygiene 2006, 3: 234-249. PMID: 16574607, DOI: 10.1080/15459620600628704.Peer-Reviewed Original ResearchConceptsWorkplace protection factorsIsocyanate exposureHalf-facepiece respiratorsRespiratory protectionFit factorsRespiratory protection programTotal isocyanate groupRespirator Fit FactorsOrganic vapor cartridgesShort-term exposure limitNegative pressureGM concentrationsPriming activitySignificant differencesExposure limitsUse trainingExposureRespiratorsProtection factorSecond testWorkersPortaCount