2022
Association of Disease‐Specific Health Status With Long‐Term Survival in Peripheral Artery Disease
Tran AT, Spertus JA, Mena‐Hurtado C, Jones PG, Aronow HD, Safley DM, Malik AO, Peri‐Okonny P, Shishehbor MH, Labrosciano C, Smolderen KG. Association of Disease‐Specific Health Status With Long‐Term Survival in Peripheral Artery Disease. Journal Of The American Heart Association 2022, 11: e022232. PMID: 35132874, PMCID: PMC9245831, DOI: 10.1161/jaha.121.022232.Peer-Reviewed Original ResearchConceptsPeripheral artery diseasePAD-specific health statusHealth statusPAD symptomsArtery diseaseHierarchical Cox regression modelsDisease-specific health statusLong-term mortality riskTime of diagnosisCox regression modelLong-term survivalPORTRAIT registryCardiovascular morbidityCause mortalityResults PatientsKaplan-MeierMortality riskUnadjusted modelsSummary scoresUS sitesPatientsMortalityBaselineSymptomsDisease
2021
Association of sleep apnea with outcomes in peripheral artery disease: Insights from the PORTRAIT study
Jelani QU, Mena-Hurtado C, Gosch K, Mohammed M, Labrosciano C, Regan C, Scierka LE, Spertus JA, Nagpal S, Smolderen KG. Association of sleep apnea with outcomes in peripheral artery disease: Insights from the PORTRAIT study. PLOS ONE 2021, 16: e0256933. PMID: 34506511, PMCID: PMC8432750, DOI: 10.1371/journal.pone.0256933.Peer-Reviewed Original ResearchConceptsPeripheral artery diseasePeripheral Artery QuestionnaireSleep apneaHealth statusArtery diseaseSummary scoresDisease-specific Peripheral Artery QuestionnaireFive-year survival curvesHigh ankle-brachial indexPAQ summary scoreVascular specialty clinicsAnkle-brachial indexLog-rank testSleep apnea statusHealth status outcomesWorse health statusQuality of lifeBetter health statusCause mortalityMultivariable adjustmentPAD symptomsCoronary diseasePeripheral interventionsUS patientsMean ageEstablishing Thresholds for Minimal Clinically Important Differences for the Peripheral Artery Disease Questionnaire
Peri-Okonny PA, Wang J, Gosch KL, Patel MR, Shishehbor MH, Safley DL, Abbott JD, Aronow HD, Mena-Hurtado C, Jelani QU, Tang Y, Bunte M, Labrosciano C, Beltrame JF, Spertus JA, Smolderen KG. Establishing Thresholds for Minimal Clinically Important Differences for the Peripheral Artery Disease Questionnaire. Circulation Cardiovascular Quality And Outcomes 2021, 14: e007232. PMID: 33947205, PMCID: PMC8254614, DOI: 10.1161/circoutcomes.120.007232.Peer-Reviewed Original ResearchConceptsPAQ summary scorePeripheral Artery QuestionnaireGlobal assessmentPatient's perspectiveSummary scoresDisease-specific health status instrumentHealth status assessment toolMinimal Clinically Important DifferencePAQ scoresPatient-reported outcomesRoutine clinical careHealth status instrumentsClinically Important DifferenceMultivariable linear regressionPORTRAIT registryDisease QuestionnaireMultivariable adjustmentVascular clinicMean ageUS cohortClinical trialsClinical careMCIDMCID estimatesMean difference
2020
Association of perceived stress with health status outcomes in patients with peripheral artery disease
Malik AO, Peri-Okonny P, Gosch K, Thomas MB, Mena-Hurtado C, Hiatt W, Aronow HD, Jones PG, Provance J, Labrosciano C, Jelani QU, Spertus JA, Smolderen KG. Association of perceived stress with health status outcomes in patients with peripheral artery disease. Journal Of Psychosomatic Research 2020, 140: 110313. PMID: 33279876, PMCID: PMC8130536, DOI: 10.1016/j.jpsychores.2020.110313.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseHealth status outcomesArtery diseaseStatus outcomesSelf-perceived stressSummary scoresDisease-specific health statusPoor recoveryHigh chronic stressProspective registryChart reviewAnalytical cohortMean ageAverage stress scoreHealth statusDisease severityPatientsChronic stressComorbiditiesSum scoreAverage exposureDiseaseStress scoresSocioeconomic statusTime pointsAssociation of Diabetes Mellitus With Health Status Outcomes in Patients With Peripheral Artery Disease: Insights From the PORTRAIT Registry
Patel KK, Alturkmani H, Gosch K, Mena‐Hurtado C, Shishehbor MH, Peri‐Okonny P, Creager MA, Spertus JA, Smolderen KG. Association of Diabetes Mellitus With Health Status Outcomes in Patients With Peripheral Artery Disease: Insights From the PORTRAIT Registry. Journal Of The American Heart Association 2020, 9: e017103. PMID: 33153398, PMCID: PMC7763706, DOI: 10.1161/jaha.120.017103.Peer-Reviewed Original ResearchConceptsPeripheral artery diseasePAQ summary scoreDiabetes mellitusHealth statusArtery diseaseSummary scoresEffect of DMInteraction of DMPAD-specific health statusSymptomatic peripheral artery diseaseAdverse limb eventsHealth status benefitsBaseline health statusHealth status outcomesPoor health statusHealth status gainsComorbidity burdenPAD progressionPAD severityPORTRAIT registryBackground PatientsConclusions PatientsInternational registryRecent exacerbationSpecialty clinicCilostazol and peripheral artery disease-specific health status in ambulatory patients with symptomatic PAD
Mohammed M, Gosch K, Safley D, Jelani QU, Aronow HD, Mena C, Shishehbor MH, Spertus JA, Abbott JD, Smolderen KG. Cilostazol and peripheral artery disease-specific health status in ambulatory patients with symptomatic PAD. International Journal Of Cardiology 2020, 316: 222-228. PMID: 32464249, DOI: 10.1016/j.ijcard.2020.05.042.Peer-Reviewed Original ResearchConceptsPeripheral Artery QuestionnaireHealth statusDisease-specific health statusPatient-reported health statusHeart failure historyNon-cilostazol groupUse of cilostazolPAQ scoresImprovement of symptomsSubsequent health statusQuality of lifeCilostazol therapyCilostazol useSymptomatic PADPatient characteristicsPharmacological optionsAmbulatory patientsLimitation scoresMean ageFunctional statusUS cohortTreatment goalsSummary scoresCilostazolPatients