2022
Fracture-Associated Microbiome and Persistent Nonunion: Next-Generation Sequencing Reveals New Findings
Goswami K, Tipton C, Clarkson S, Chang G, Tan TL, Fram B, Chisari E, Sobol K, Natoli RM, Conway JD, Altman GT, Parvizi J, Krieg JC. Fracture-Associated Microbiome and Persistent Nonunion: Next-Generation Sequencing Reveals New Findings. Journal Of Orthopaedic Trauma 2022, 36: s40-s46. PMID: 35061650, DOI: 10.1097/bot.0000000000002305.Peer-Reviewed Original ResearchConceptsPersistent nonunionLong bone nonunionOpen surgical interventionProspective multicenter studySignificant risk factorsAcute fracturesDevastating complicationIntraoperative specimensMulticenter studySurgical interventionFracture nonunionNonunion diagnosisRisk factorsNGS detectionNonunionUseful adjunctFracture healingClinical specimensPatientsClinical implicationsLevel IIMore casesNGS diagnosticsControl casesBacterial profiles
2020
Immediate Weight Bearing and Range of Motion After Internal Fixation of Unstable Ankle Fractures: A Retrospective Controlled Study
Fram B, Rogero R, Corr D, Chang G, Krieg J, Raikin S. Immediate Weight Bearing and Range of Motion After Internal Fixation of Unstable Ankle Fractures: A Retrospective Controlled Study. Foot & Ankle Orthopaedics 2020, 5: 2473011420s00216. PMCID: PMC8705062, DOI: 10.1177/2473011420s00216.Peer-Reviewed Original ResearchOpen reduction internal fixationUnstable ankle fracturesCharleston Comorbidity IndexImmediate weight bearingNon-weight bearingRange of motionAnkle fracturesWeight bearingRisk factorsInternal fixationSyndesmosis fixationPosterior malleolusAnkle fracture open reduction internal fixationPrimary open reduction internal fixationRetrospective case-control studyPosterior malleolar fixationAnkle fracture fixationReduction internal fixationPost-operative complicationsCommon fracture typeCase-control studyPosterior malleolus fragmentSpecific risk factorsBroader patient populationMaisonneuve injury