2020
Predictors of urinary and blood Metal(loid) concentrations among pregnant women in Northern Puerto Rico
Ashrap P, Watkins D, Mukherjee B, Boss J, Richards M, Rosario Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Predictors of urinary and blood Metal(loid) concentrations among pregnant women in Northern Puerto Rico. Environmental Research 2020, 183: 109178. PMID: 32007748, PMCID: PMC7167342, DOI: 10.1016/j.envres.2020.109178.Peer-Reviewed Original ResearchConceptsBlood concentrations of CuTrace metal exposureConcentrations of CuExposure reduction strategiesBiomarkers of exposureBlood HgMetalloid exposureMetal exposureNorthern Puerto RicoBlood CdTrace metalsBlood PbRice consumptionExposure sourcesPuerto RicoMetal(loid)sMetal(loidExposure assessmentBiomarker variationsPbPublic waterZnFishMnMetal
2019
Determinants of per- and polyfluoroalkyl substances (PFAS) in midlife women: Evidence of racial/ethnic and geographic differences in PFAS exposure
Park S, Peng Q, Ding N, Mukherjee B, Harlow S. Determinants of per- and polyfluoroalkyl substances (PFAS) in midlife women: Evidence of racial/ethnic and geographic differences in PFAS exposure. Environmental Research 2019, 175: 186-199. PMID: 31129528, PMCID: PMC6579633, DOI: 10.1016/j.envres.2019.05.028.Peer-Reviewed Original ResearchConceptsWhite womenIntake of salty snacksStudy of Women's HealthPoly-fluoroalkyl substancesPerfluorooctane sulfonic acidDeterminants of PFAS concentrationsDeterminants of PFAS exposurePFAS exposureConcentrations of PFASsSalty snacksWomen's HealthPublic health concernPre-specified variablesLinear perfluorooctanoic acidPerfluorooctanoic acidExposure backgroundMidlife womenHigher intakePerfluorononanoic acidLow PFAS concentrationsPFNA concentrationsBlack womenRace/ethnicityHigher concentrationsPFAS concentrations
2014
Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes
Liu C, Fonken L, Wang A, Maiseyeu A, Bai Y, Wang T, Maurya S, Ko Y, Periasamy M, Dvonch T, Morishita M, Brook R, Harkema J, Ying Z, Mukherjee B, Sun Q, Nelson R, Rajagopalan S. Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes. Particle And Fibre Toxicology 2014, 11: 53. PMID: 25358444, PMCID: PMC4226918, DOI: 10.1186/s12989-014-0053-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAnti-Inflammatory AgentsBenzamidesBlood GlucoseDiabetes Mellitus, Type 2Disease Models, AnimalEnergy MetabolismHypothalamusI-kappa B KinaseInflammationInfliximabInhalation ExposureInjections, IntraventricularInsulinInsulin ResistanceInterleukin-6MiceOxygen ConsumptionParticulate MatterProtein Kinase InhibitorsRisk AssessmentRNA, MessengerThermogenesisTime FactorsTumor Necrosis Factor-alphaNo effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function
Maiseyeu A, Yang H, Ramanathan G, Yin F, Bard R, Morishita M, Dvonch J, Wang L, Spino C, Mukherjee B, Badgeley M, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo J, Brook R. No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function. Inhalation Toxicology 2014, 26: 23-29. PMID: 24417404, PMCID: PMC4445365, DOI: 10.3109/08958378.2013.850761.Peer-Reviewed Original ResearchConceptsRural locationsParticulate matter air pollutionHDL dysfunctionHDL anti-oxidative capacityRandomized double-blind crossover studyDouble-blind crossover studyHDL functionHDL-mediated cholesterol efflux capacityParaoxonase activityFiltered airVascular protective functionCholesterol efflux capacityHigh-density lipoprotein (HDL) particlesMetrics of HDL functionHDL-mediated effluxConcentrated ambient particlesCrossover studyImpact of PMEfflux capacityPM exposureVenous bloodAnimal studiesHealthy humansCoarse PMWilcoxon test
2013
Cardiovascular Depression in Rats Exposed to Inhaled Particulate Matter and Ozone: Effects of Diet-Induced Metabolic Syndrome
Wagner J, Allen K, Yang H, Nan B, Morishita M, Mukherjee B, Dvonch J, Spino C, Fink G, Rajagopalan S, Sun Q, Brook R, Harkema J. Cardiovascular Depression in Rats Exposed to Inhaled Particulate Matter and Ozone: Effects of Diet-Induced Metabolic Syndrome. Environmental Health Perspectives 2013, 122: 27-33. PMID: 24169565, PMCID: PMC3888573, DOI: 10.1289/ehp.1307085.Peer-Reviewed Original ResearchConceptsHFrD ratsBlood pressureND ratsHeart rateMetabolic syndromeHR variabilityFasting levels of blood glucoseNormal dietMale Sprague-Dawley ratsParticulate matterAssociated with cardiovascular morbidityCardiovascular depressionAir pollutionSprague-Dawley ratsDiet-induced metabolic syndromeElevated fasting levelsToxicity of air pollutantsFine particulate matterHigh-fructose dietLevels of blood glucoseInhalable particulate matterLevels of ozoneInduce MetSCardiovascular morbidityExaggerated BP
2011
PM2.5-induced changes in cardiac function of hypertensive rats depend on wind direction and specific sources in Steubenville, Ohio
Kamal A, Rohr A, Mukherjee B, Morishita M, Keeler G, Harkema J, Wagner J. PM2.5-induced changes in cardiac function of hypertensive rats depend on wind direction and specific sources in Steubenville, Ohio. Inhalation Toxicology 2011, 23: 417-430. PMID: 21639710, DOI: 10.3109/08958378.2011.580387.Peer-Reviewed Original ResearchConceptsNE windsSW windsSource factorsMobile source factorsPositive matrix factorizationConcentrated ambient particlesPotential emission sourcesSources of PM(2.5Adverse health effectsPM constituentsWind directionParticulate matterMobile sourcesIndividual elemental componentsTrace elementsAmbient particlesIron/steel productionPM(2.5IncinerationAmbient PM(2.5Metal factorWindHealth effectsExposure to concentrated ambient particlesSouthwest
2010
Altered Heart Rate Variability in Spontaneously Hypertensive Rats Is Associated with Specific Particulate Matter Components in Detroit, Michigan
Rohr A, Kamal A, Morishita M, Mukherjee B, Keeler G, Harkema J, Wagner J. Altered Heart Rate Variability in Spontaneously Hypertensive Rats Is Associated with Specific Particulate Matter Components in Detroit, Michigan. Environmental Health Perspectives 2010, 119: 474-480. PMID: 21163724, PMCID: PMC3080928, DOI: 10.1289/ehp.1002831.Peer-Reviewed Original ResearchConceptsSource factorsPositive matrix factorizationNormal-to-normal intervalsLocal industrial sourcesParticulate matter componentsFine particulate matterSludge factorSemicontinuous ElementsSludge incinerationAerosol samplerAdverse cardiopulmonary health effectsAmbient particlesHeart rate variabilityExposure to fine particulate matterParticulate matterSulfation factorWinterRoot mean squareIndustrial sourcesIncreased root mean squareSummerCement/limeAnalytical resultsHeart rateSludge
2009
Case–Control Studies of Gene–Environment Interaction: Bayesian Design and Analysis
Mukherjee B, Ahn J, Gruber S, Ghosh M, Chatterjee N. Case–Control Studies of Gene–Environment Interaction: Bayesian Design and Analysis. Biometrics 2009, 66: 934-948. PMID: 19930190, PMCID: PMC3103064, DOI: 10.1111/j.1541-0420.2009.01357.x.Peer-Reviewed Original ResearchConceptsGene-environment interactionsCase-control study of colorectal cancerStudy of gene-environment interactionsStudy of colorectal cancerGene-environment independenceRed meat consumptionBayesian designCase-control studyBayesian approachSample size determination criteriaCase-controlEpidemiological studiesColorectal cancerFrequentist counterpartsNatural wayMeat consumptionAnalyze current dataHypothesis testingDetermination criteriaSmokingEpidemiological exposureAnalysis strategyStudySustainable Control of Water-Related Infectious Diseases: A Review and Proposal for Interdisciplinary Health-Based Systems Research
Batterman S, Eisenberg J, Hardin R, Kruk M, Lemos M, Michalak A, Mukherjee B, Renne E, Stein H, Watkins C, Wilson M. Sustainable Control of Water-Related Infectious Diseases: A Review and Proposal for Interdisciplinary Health-Based Systems Research. Environmental Health Perspectives 2009, 117: 1023-1032. PMID: 19654908, PMCID: PMC2717125, DOI: 10.1289/ehp.0800423.Peer-Reviewed Original Research
2008
Modeling Unobserved Sources of Heterogeneity in Animal Abundance Using a Dirichlet Process Prior
Dorazio R, Mukherjee B, Zhang L, Ghosh M, Jelks H, Jordan F. Modeling Unobserved Sources of Heterogeneity in Animal Abundance Using a Dirichlet Process Prior. Biometrics 2008, 64: 635-644. PMID: 17680831, DOI: 10.1111/j.1541-0420.2007.00873.x.Peer-Reviewed Original ResearchConceptsSampling locationsSampling protocolNatural populations of animalsPredictions of abundanceAbundance of animalsDistribution of abundanceEndangered fish speciesInduce spatial heterogeneityAnimal abundanceOkaloosa DartersPopulations of animalsUnsampled locationsFish speciesRemoval samplingSpatial heterogeneityAnalysis of countsAbundanceDirichlet processData-adaptive wayModel specificationSources of heterogeneitySpeciesParametric alternativesDartersParametric model
2006
A Score Test for Determining Sample Size in Matched Case‐Control Studies with Categorical Exposure
Sinha S, Mukherjee B. A Score Test for Determining Sample Size in Matched Case‐Control Studies with Categorical Exposure. Biometrical Journal 2006, 48: 35-53. PMID: 16544811, DOI: 10.1002/bimj.200510200.Peer-Reviewed Original ResearchConceptsCase-control studyCategorical exposureMatched case-control studyScore testDichotomous exposureNull hypothesisExposure variablesOdds ratioNatural orderDisease-gene associationsMatched setsDisease riskColorectal cancerPower functionSample sizeAssociationOddsGeneralizationDiseaseSetsScoresEstimationExposureStudyRisk