2024
Cross-shift changes in pulmonary function and occupational exposure to particulate matter among e-waste workers in Ghana
Laskaris Z, O'Neill M, Batterman S, Mukherjee B, Fobil J, Robins T. Cross-shift changes in pulmonary function and occupational exposure to particulate matter among e-waste workers in Ghana. Frontiers In Public Health 2024, 12: 1368112. PMID: 38784567, PMCID: PMC11111984, DOI: 10.3389/fpubh.2024.1368112.Peer-Reviewed Original ResearchConceptsE-waste workersExposure to particulate matterE-wasteParticulate matterAgbogbloshie e-waste siteInhalation exposure to particulate matterE-waste sitesBurning e-wasteConcentrations of PMHealth-based guidelinesExposure to airborne pollutantsExposure to PMOccupational exposure to particulate matterCross-shift changesElectronic-wasteForced vital capacityPersonal PMPM exposureAirborne pollutantsLinear mixed modelsBreathing zone concentrationsPulmonary functionComparison populationRecovery workersMixed models
2022
Associations of self-reported occupational exposures and settings to ALS: a case–control study
Goutman S, Boss J, Godwin C, Mukherjee B, Feldman E, Batterman S. Associations of self-reported occupational exposures and settings to ALS: a case–control study. International Archives Of Occupational And Environmental Health 2022, 95: 1567-1586. PMID: 35593931, PMCID: PMC9424174, DOI: 10.1007/s00420-022-01874-4.Peer-Reviewed Original ResearchConceptsStandard Occupational ClassificationStandard Occupational Classification codesExposure to particulate matterProductive occupationsALS riskSelf-reported occupational exposureHigher risk of amyotrophic lateral sclerosisOccupational exposureHigher ALS riskRisk of amyotrophic lateral sclerosisRisk factor modificationOccupational exposure to particulate matterExposure surveyIncreased ALS riskCase-control studyMaintenance occupationsGrounds cleaningFactor modificationExposure scoreTargeted screeningAmyotrophic lateral sclerosis diagnosisRepair occupationsAdaptive elastic net modelOccupational classificationProgressive neurological disease
2021
Exposure to Primary Air Pollutants Generated by Highway Traffic and Daily Mortality Risk in Near-Road Communities: A Case-Crossover Study
Filigrana P, Milando C, Batterman S, Levy J, Mukherjee B, Pedde M, Szpiro A, Adar S. Exposure to Primary Air Pollutants Generated by Highway Traffic and Daily Mortality Risk in Near-Road Communities: A Case-Crossover Study. American Journal Of Epidemiology 2021, 191: 63-74. PMID: 34347034, DOI: 10.1093/aje/kwab215.Peer-Reviewed Original ResearchConceptsNear-road populationsAir pollutionMortality riskExposure to traffic-related air pollutionAverage PM2.5 exposureTraffic-generated air pollutionNear-road communitiesResearch LINE sourceConcentrations of PM2.5Traffic-related air pollutionCase-crossover designPrimary air pollutantsConditional logistic regressionPuget Sound area of Washington StateDaily mortality riskCase-crossoverTime-varying covariatesCerebrovascular mortalityPM2.5 exposurePrimary pollutantsQuantify associationsAerodynamic diameterShorter averaging periodsPM2.5PollutionOpportunities and challenges in reducing personal inhalation exposure to air pollution among electronic waste recovery workers in Ghana
Laskaris Z, Batterman S, Arko‐Mensah J, Mukherjee B, Fobil J, O'Neill M, Robins T. Opportunities and challenges in reducing personal inhalation exposure to air pollution among electronic waste recovery workers in Ghana. American Journal Of Industrial Medicine 2021, 64: 381-397. PMID: 33522624, PMCID: PMC8046737, DOI: 10.1002/ajim.23229.Peer-Reviewed Original ResearchConceptsPersonal PM<sub>2.5</sub>Burning e-wasteE-wasteHigh PM<sub>2.5</sub> concentrationsAgbogbloshie e-waste siteExposure to air pollutionExposure to particulate matterSize-specific PMInhalation exposure to particulate matterE-waste sitesE-waste workersLevels of PMPM samplesParticulate matterBurning activitiesAir pollutionTime-activityTime-activity dataElectronic wasteWorker's breathing zonePersonal samplesToxic emissionsLinear mixed modelsSite locationWind direction
2019
Derivation of Time-Activity Data Using Wearable Cameras and Measures of Personal Inhalation Exposure among Workers at an Informal Electronic-Waste Recovery Site in Ghana
Laskaris Z, Milando C, Batterman S, Mukherjee B, Basu N, O’neill M, Robins T, Fobil J. Derivation of Time-Activity Data Using Wearable Cameras and Measures of Personal Inhalation Exposure among Workers at an Informal Electronic-Waste Recovery Site in Ghana. Annals Of Work Exposures And Health 2019, 63: 829-841. PMID: 31334545, PMCID: PMC6788341, DOI: 10.1093/annweh/wxz056.Peer-Reviewed Original ResearchConceptsTime-activity patternsTime-activity dataPM2.5 exposureAgbogbloshie e-waste siteE-waste sitesRecovery sitesExposure to workplace hazardsReal-time particle monitorsNon-work-related activitiesPersonal inhalation exposureWearable camerasE-waste materialsPM2.5 levelsElectronic-wasteWorld Health Organization standardsWorld Health OrganizationParticulate matterPM2.5E-wasteWorkplace hazardsTime-activityBillion workersMetal recoveryExposure assessmentOccupational hazards
2015
Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance
Brook R, Sun Z, Brook J, Zhao X, Ruan Y, Yan J, Mukherjee B, Rao X, Duan F, Sun L, Liang R, Lian H, Zhang S, Fang Q, Gu D, Sun Q, Fan Z, Rajagopalan S. Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance. Hypertension 2015, 67: 77-85. PMID: 26573709, PMCID: PMC4830086, DOI: 10.1161/hypertensionaha.115.06237.Peer-Reviewed Original ResearchConceptsFine particulate matterParticulate matterAmbient fine particulate matterSD increaseAssociated with worsening insulin resistanceBlack carbon levelsBlack carbon exposurePublic health warningsAir pollutionBeijing metropolitan areaBlack carbonHealth warningsAssociated with rangeCardiometabolic healthCarbon levelsDiastolic blood pressureExposure windowsCardiometabolic diseasesHealth effectsNonsmoking adultsMetabolic syndromeDeveloping world todayCarbon exposureSystolic blood pressure elevationHealth
2014
Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes
Liu C, Fonken L, Wang A, Maiseyeu A, Bai Y, Wang T, Maurya S, Ko Y, Periasamy M, Dvonch T, Morishita M, Brook R, Harkema J, Ying Z, Mukherjee B, Sun Q, Nelson R, Rajagopalan S. Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes. Particle And Fibre Toxicology 2014, 11: 53. PMID: 25358444, PMCID: PMC4226918, DOI: 10.1186/s12989-014-0053-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAnti-Inflammatory AgentsBenzamidesBlood GlucoseDiabetes Mellitus, Type 2Disease Models, AnimalEnergy MetabolismHypothalamusI-kappa B KinaseInflammationInfliximabInhalation ExposureInjections, IntraventricularInsulinInsulin ResistanceInterleukin-6MiceOxygen ConsumptionParticulate MatterProtein Kinase InhibitorsRisk AssessmentRNA, MessengerThermogenesisTime FactorsTumor Necrosis Factor-alphaThe characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures
Morishita M, Bard R, Wang L, Das R, Dvonch J, Spino C, Mukherjee B, Sun Q, Harkema J, Rajagopalan S, Brook R. The characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures. Journal Of Exposure Science & Environmental Epidemiology 2014, 25: 153-159. PMID: 25227729, PMCID: PMC4462122, DOI: 10.1038/jes.2014.62.Peer-Reviewed Original ResearchConceptsCoarse PMPM massEffects of coarse PMCoarse PM massAmbient coarse PMRural locationsSystolic BPMetrics of exposureBlood pressurePotential health effectsHeart ratePM elementsElevated systolic BPFiltered airAerodynamic diameterDiastolic BP changesMixed model analysisConcentration-response mannerParticulate massFilter samplesParticle constituentsDiastolic BPMeasured elementsHealthy adultsAssociated with similar degreesPersonal exposure to mixtures of volatile organic compounds: modeling and further analysis of the RIOPA data.
Batterman S, Su F, Li S, Mukherjee B, Jia C. Personal exposure to mixtures of volatile organic compounds: modeling and further analysis of the RIOPA data. Research Report 2014, 3-63. PMID: 25145040, PMCID: PMC4577247.Peer-Reviewed Original ResearchConceptsPositive matrix factorizationCumulative cancer riskAir exchange rateVOC exposureToxicological mode of actionMethod detection limitsPersonal exposureVolatile organic compoundsOutdoor concentrationsVOC mixturesVOC concentrationsEmission sourcesEmission sources of volatile organic compoundsHome air exchange ratesLinear mixed-effects modelsSources of volatile organic compoundsLifetime cumulative cancer riskToxicological modeVOC dataIndividual VOCsVariables associated with exposureRelationship of IndoorIndoor VOC concentrationsCancer riskHealth-based guidelinesHemodynamic, Autonomic, and Vascular Effects of Exposure to Coarse Particulate Matter Air Pollution from a Rural Location
Brook R, Bard R, Morishita M, Dvonch J, Wang L, Yang H, Spino C, Mukherjee B, Kaplan M, Yalavarthi S, Oral E, Ajluni N, Sun Q, Brook J, Harkema J, Rajagopalan S. Hemodynamic, Autonomic, and Vascular Effects of Exposure to Coarse Particulate Matter Air Pollution from a Rural Location. Environmental Health Perspectives 2014, 122: 624-630. PMID: 24618231, PMCID: PMC4050508, DOI: 10.1289/ehp.1306595.Peer-Reviewed Original ResearchConceptsCoarse PMParticulate matterAir pollutionRural locationsCoarse particlesParticulate matter air pollutionCoarse PM exposureAssociated with numerous adverse health effectsAcute CV eventsBlood pressureFine particulate matterAmbient coarse particlesNumerous adverse health effectsGlobal air pollutionAdverse health effectsHeart rateFrequency heart rate variabilityCoarse CAPPM exposureFiltered airRandomized double-blind crossover studyDiastolic BPDouble-blind crossover studyHealth effectsHealthy adultsNo effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function
Maiseyeu A, Yang H, Ramanathan G, Yin F, Bard R, Morishita M, Dvonch J, Wang L, Spino C, Mukherjee B, Badgeley M, Barajas-Espinosa A, Sun Q, Harkema J, Rajagopalan S, Araujo J, Brook R. No effect of acute exposure to coarse particulate matter air pollution in a rural location on high-density lipoprotein function. Inhalation Toxicology 2014, 26: 23-29. PMID: 24417404, PMCID: PMC4445365, DOI: 10.3109/08958378.2013.850761.Peer-Reviewed Original ResearchConceptsRural locationsParticulate matter air pollutionHDL dysfunctionHDL anti-oxidative capacityRandomized double-blind crossover studyDouble-blind crossover studyHDL functionHDL-mediated cholesterol efflux capacityParaoxonase activityFiltered airVascular protective functionCholesterol efflux capacityHigh-density lipoprotein (HDL) particlesMetrics of HDL functionHDL-mediated effluxConcentrated ambient particlesCrossover studyImpact of PMEfflux capacityPM exposureVenous bloodAnimal studiesHealthy humansCoarse PMWilcoxon testPersonal Black Carbon Exposure Influences Ambulatory Blood Pressure
Zhao X, Sun Z, Ruan Y, Yan J, Mukherjee B, Yang F, Duan F, Sun L, Liang R, Lian H, Zhang S, Fang Q, Gu D, Brook J, Sun Q, Brook R, Rajagopalan S, Fan Z. Personal Black Carbon Exposure Influences Ambulatory Blood Pressure. Hypertension 2014, 63: 871-877. PMID: 24420543, PMCID: PMC4445364, DOI: 10.1161/hypertensionaha.113.02588.Peer-Reviewed Original ResearchConceptsPersonal black carbonAir pollutionBlack carbonBeijing Municipal Environmental Monitoring CenterFine particulate matter concentrationsCombustion-related air pollutionFine particulate matterAmbulatory blood pressureEnvironmental Monitoring CenterParticulate matter concentrationsBlood pressureHigh air pollutionReduce air pollutionMm HgLow frequency to high frequency ratioPublic health effectsParticulate matterTwenty-four-hour ambulatory blood pressureExposure to high levelsMatter concentrationSystolic blood pressureDiastolic blood pressurePollutionBlood pressure effectsGeneralized linear model
2013
Cardiovascular Depression in Rats Exposed to Inhaled Particulate Matter and Ozone: Effects of Diet-Induced Metabolic Syndrome
Wagner J, Allen K, Yang H, Nan B, Morishita M, Mukherjee B, Dvonch J, Spino C, Fink G, Rajagopalan S, Sun Q, Brook R, Harkema J. Cardiovascular Depression in Rats Exposed to Inhaled Particulate Matter and Ozone: Effects of Diet-Induced Metabolic Syndrome. Environmental Health Perspectives 2013, 122: 27-33. PMID: 24169565, PMCID: PMC3888573, DOI: 10.1289/ehp.1307085.Peer-Reviewed Original ResearchConceptsHFrD ratsBlood pressureND ratsHeart rateMetabolic syndromeHR variabilityFasting levels of blood glucoseNormal dietMale Sprague-Dawley ratsParticulate matterAssociated with cardiovascular morbidityCardiovascular depressionAir pollutionSprague-Dawley ratsDiet-induced metabolic syndromeElevated fasting levelsToxicity of air pollutantsFine particulate matterHigh-fructose dietLevels of blood glucoseInhalable particulate matterLevels of ozoneInduce MetSCardiovascular morbidityExaggerated BPThe effect of acute exposure to coarse particulate matter air pollution in a rural location on circulating endothelial progenitor cells: results from a randomized controlled study
Brook R, Bard R, Kaplan M, Yalavarthi S, Morishita M, Dvonch J, Wang L, Yang H, Spino C, Mukherjee B, Oral E, Sun Q, Brook J, Harkema J, Rajagopalan S. The effect of acute exposure to coarse particulate matter air pollution in a rural location on circulating endothelial progenitor cells: results from a randomized controlled study. Inhalation Toxicology 2013, 25: 587-592. PMID: 23919441, PMCID: PMC4364610, DOI: 10.3109/08958378.2013.814733.Peer-Reviewed Original ResearchMeSH KeywordsAdultCross-Over StudiesEndothelial CellsFemaleHumansMaleParticle SizeParticulate MatterRural PopulationStem CellsYoung AdultConceptsCirculating endothelial progenitor cellsRural locationsVascular endothelial growth factorEndothelial progenitor cellsCirculating EPC levelsCoarse PMWhite blood cellsParticulate matterConcentrated ambient particlesParticulate matter air pollutionAir pollutionFine particulate matterEPC levelsProgenitor cellsWilcoxon signed-rank testRandomized double-blind crossover studyDouble-blind crossover studyFiltered airSigned-rank testBlood cellsPeripheral venous bloodSympathetic nervous system activityEndothelial growth factorAssociated with alterationsCardiovascular disease
2012
Air pollution and respiratory symptoms among children with asthma: Vulnerability by corticosteroid use and residence area
Lewis T, Robins T, Mentz G, Zhang X, Mukherjee B, Lin X, Keeler G, Dvonch J, Yip F, O'Neill M, Parker E, Israel B, Max P, Reyes A, Committee C. Air pollution and respiratory symptoms among children with asthma: Vulnerability by corticosteroid use and residence area. The Science Of The Total Environment 2012, 448: 48-55. PMID: 23273373, PMCID: PMC4327853, DOI: 10.1016/j.scitotenv.2012.11.070.Peer-Reviewed Original ResearchConceptsParticulate matterAir pollutionAssociated with negative health impactsAmbient pollutant concentrationsAir quality standardsAmbient air pollutionAmbient particulate matterEffective risk reduction interventionsOdds of respiratory symptomsAsthmatic childrenFactors associated with heterogeneityAssociated with increased oddsObserved health effectsRespiratory symptomsRisk reduction interventionsPopulation of asthmatic childrenRespiratory symptom diariesOutdoor PMDaily concentrationsPollutant concentrationsMonitoring sitesGeneralized estimating equationsPollution modelLogistic regression modelsAerodynamic diameterAir-Pollution and Cardiometabolic Diseases (AIRCMD): A prospective study investigating the impact of air pollution exposure and propensity for type II diabetes
Sun Z, Mukherjee B, Brook R, Gatts G, Yang F, Sun Q, Brook J, Fan Z, Rajagopalan S. Air-Pollution and Cardiometabolic Diseases (AIRCMD): A prospective study investigating the impact of air pollution exposure and propensity for type II diabetes. The Science Of The Total Environment 2012, 448: 72-78. PMID: 23182147, PMCID: PMC4548977, DOI: 10.1016/j.scitotenv.2012.10.087.Peer-Reviewed Original ResearchConceptsAir pollution exposureAir pollutionAmbient fine particulate matterMeasures of air pollution exposureImpact of air pollution exposureFine particulate matterExposure to PM2.5Air pollution measurementsPersonal exposure measurementsCreation of novel methodologiesSub-acute exposurePolluted urban environmentsImpact of environmental factorsParticulate matterPollution exposureStudy visitsPollution measurementsType II diabetesProspective cohort studyEnvironmental risk factorsAmbient measurementsII diabetesCohort studyUrban environmentScreening visitParticulate matter concentrations in residences: an intervention study evaluating stand‐alone filters and air conditioners
Batterman S, Du L, Mentz G, Mukherjee B, Parker E, Godwin C, Chin J, O’Toole A, Robins T, Rowe Z, Lewis T. Particulate matter concentrations in residences: an intervention study evaluating stand‐alone filters and air conditioners. Indoor Air 2012, 22: 235-252. PMID: 22145709, PMCID: PMC4233141, DOI: 10.1111/j.1600-0668.2011.00761.x.Peer-Reviewed Original ResearchMeSH KeywordsAir ConditioningAir Pollution, IndoorAsthmaChildHumansModels, StatisticalParticulate MatterSeasonsConceptsEnvironmental tobacco smokeIndoor air qualityParticulate matterPM levelsPM concentrationsExchange ratioIntervention studiesAir qualityHigh concentrations of particulate matterConcentrations of particulate matterEffectiveness of interventionsOutdoor PM levelsParticulate matter concentrationsAir filtersRandomized controlled trialsChild's sleeping areaCharacterize air qualityExposure misclassificationEffective interventionsTobacco smokeChild's bedroomIncreased particulate matterMatter concentrationHouseholds of childrenStudy population
2011
PM2.5-induced changes in cardiac function of hypertensive rats depend on wind direction and specific sources in Steubenville, Ohio
Kamal A, Rohr A, Mukherjee B, Morishita M, Keeler G, Harkema J, Wagner J. PM2.5-induced changes in cardiac function of hypertensive rats depend on wind direction and specific sources in Steubenville, Ohio. Inhalation Toxicology 2011, 23: 417-430. PMID: 21639710, DOI: 10.3109/08958378.2011.580387.Peer-Reviewed Original ResearchConceptsNE windsSW windsSource factorsMobile source factorsPositive matrix factorizationConcentrated ambient particlesPotential emission sourcesSources of PM(2.5Adverse health effectsPM constituentsWind directionParticulate matterMobile sourcesIndividual elemental componentsTrace elementsAmbient particlesIron/steel productionPM(2.5IncinerationAmbient PM(2.5Metal factorWindHealth effectsExposure to concentrated ambient particlesSouthwest
2010
Altered Heart Rate Variability in Spontaneously Hypertensive Rats Is Associated with Specific Particulate Matter Components in Detroit, Michigan
Rohr A, Kamal A, Morishita M, Mukherjee B, Keeler G, Harkema J, Wagner J. Altered Heart Rate Variability in Spontaneously Hypertensive Rats Is Associated with Specific Particulate Matter Components in Detroit, Michigan. Environmental Health Perspectives 2010, 119: 474-480. PMID: 21163724, PMCID: PMC3080928, DOI: 10.1289/ehp.1002831.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAnimalsDose-Response Relationship, DrugEnvironmental MonitoringHeart RateHypertensionMaleMichiganParticulate MatterRatsConceptsSource factorsPositive matrix factorizationNormal-to-normal intervalsLocal industrial sourcesParticulate matter componentsFine particulate matterSludge factorSemicontinuous ElementsSludge incinerationAerosol samplerAdverse cardiopulmonary health effectsAmbient particlesHeart rate variabilityExposure to fine particulate matterParticulate matterSulfation factorWinterRoot mean squareIndustrial sourcesIncreased root mean squareSummerCement/limeAnalytical resultsHeart rateSludge