2016
Incretin-based therapy in type 2 diabetes: An evidence based systematic review and meta-analysis
Waldrop G, Zhong J, Peters M, Goud A, Chen Y, Davis S, Mukherjee B, Rajagopalan S. Incretin-based therapy in type 2 diabetes: An evidence based systematic review and meta-analysis. Journal Of Diabetes And Its Complications 2016, 32: 113-122. PMID: 29074120, DOI: 10.1016/j.jdiacomp.2016.08.018.Peer-Reviewed Original ResearchConceptsDipeptidyl peptidase-4 inhibitorsOral anti-diabetic agentsGLP-1RABackground therapyGlycemic efficacyWeight lossGlucagon-like peptide-1 receptor agonistsPeptide-1 receptor agonistsActive comparator armLong-acting GLP-1RAType 2 diabetes mellitusPeptidase-4 inhibitorsTreatment of type 2 diabetes mellitusIncretin-based therapiesActive comparator drugShort-acting agentsWeight loss effectsClinical trial evidenceType 2 diabetesRandomized controlled trialsReceptor agonistsAnti-diabetic agentsIncretin therapiesComparator armComparator therapy
2014
Endogenous sex steroid hormones and glucose in a South‐Asian population without diabetes: the Metabolic Syndrome and Atherosclerosis in South‐Asians Living in America pilot study
Needham B, Kim C, Mukherjee B, Bagchi P, Stanczyk F, Kanaya A. Endogenous sex steroid hormones and glucose in a South‐Asian population without diabetes: the Metabolic Syndrome and Atherosclerosis in South‐Asians Living in America pilot study. Diabetic Medicine 2014, 32: 1193-1200. PMID: 25443798, PMCID: PMC4449322, DOI: 10.1111/dme.12642.Peer-Reviewed Original ResearchConceptsEndogenous sex steroid hormonesLevels of sex hormone-binding globulinAssociated with elevated fasting glucose levelsSex steroid hormonesSex hormone-binding globulinElevated fasting glucose levelsHormone-binding globulinSex steroid hormone levelsFasting glucose levelsSteroid hormone levelsGlucose levelsHepatic adipositySteroid hormonesWaist circumferenceMetabolic syndromeHigher levels of free testosteroneHormone levelsInsulin resistanceLevels of total testosteroneSouth Asian populationLevels of free testosteroneExogenous sex steroidsSouth AsiansAge-adjusted modelsAsian Indian originCentral IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes
Liu C, Fonken L, Wang A, Maiseyeu A, Bai Y, Wang T, Maurya S, Ko Y, Periasamy M, Dvonch T, Morishita M, Brook R, Harkema J, Ying Z, Mukherjee B, Sun Q, Nelson R, Rajagopalan S. Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes. Particle And Fibre Toxicology 2014, 11: 53. PMID: 25358444, PMCID: PMC4226918, DOI: 10.1186/s12989-014-0053-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAnti-Inflammatory AgentsBenzamidesBlood GlucoseDiabetes Mellitus, Type 2Disease Models, AnimalEnergy MetabolismHypothalamusI-kappa B KinaseInflammationInfliximabInhalation ExposureInjections, IntraventricularInsulinInsulin ResistanceInterleukin-6MiceOxygen ConsumptionParticulate MatterProtein Kinase InhibitorsRisk AssessmentRNA, MessengerThermogenesisTime FactorsTumor Necrosis Factor-alpha
2013
Propensity score‐based diagnostics for categorical response regression models
Boonstra P, Bondarenko I, Park S, Vokonas P, Mukherjee B. Propensity score‐based diagnostics for categorical response regression models. Statistics In Medicine 2013, 33: 455-469. PMID: 23934948, PMCID: PMC3911784, DOI: 10.1002/sim.5940.Peer-Reviewed Original ResearchConceptsRetrospective sampling designsChi-square distributionCategorical response modelsGoodness-of-fit statisticsPredicted response probabilitiesResponse regression modelsConditional distributionProportional odds modelAssess model adequacyData examplesSimulation studyVA Normative Aging StudyNormative Aging StudyPropensity scoreCumulative lead exposureOdds modelModel diagnosticsCase-control studyAssociated with diabetesBalance scoresResponse probabilityModel adequacyCohort studyAging StudyNumerical summaries
2009
Graphical diagnostics to check model misspecification for the proportional odds regression model
Liu I, Mukherjee B, Suesse T, Sparrow D, Park S. Graphical diagnostics to check model misspecification for the proportional odds regression model. Statistics In Medicine 2009, 28: 412-429. PMID: 18693299, DOI: 10.1002/sim.3386.Peer-Reviewed Original ResearchConceptsCovariate effectsOrdinal responsesModel misspecificationProportional odds regression modelStudy covariate effectsGoodness-of-fit statisticsClass of modelsNumerical methodFunctional misspecificationBinary responsesGraphical diagnosticsSimulation studyCumulative logitsMisspecificationCumulative sumRegression modelsGraphical methodSumArbogastVA Normative Aging StudyCovariatesProportional odds regressionClass