2018
Associations between maternal plasma measurements of inflammatory markers and urinary levels of phenols and parabens during pregnancy: A repeated measures study
Aung M, Ferguson K, Cantonwine D, Bakulski K, Mukherjee B, Loch-Caruso R, McElrath T, Meeker J. Associations between maternal plasma measurements of inflammatory markers and urinary levels of phenols and parabens during pregnancy: A repeated measures study. The Science Of The Total Environment 2018, 650: 1131-1140. PMID: 30308801, PMCID: PMC6236678, DOI: 10.1016/j.scitotenv.2018.08.356.Peer-Reviewed Original ResearchConceptsPlasma inflammatory markersInflammatory markersC-reactive proteinInterquartile range increaseFetal developmentImmunological biomarkersRange increaseTumor necrosis factor-aCase-control studyProspective birth cohortImmune system regulationHealthy pregnancyUrinary phenolSystemic inflammationImmunological mechanismsInterleukin-10Urinary levelsInterleukin-1bPregnancyStudy visitsMultivariate linear mixed modelReproductive outcomesMeasures of exposureInverse probability weightingUrine samples
2017
Subclinical Changes in Maternal Thyroid Function Parameters in Pregnancy and Fetal Growth
Johns L, Ferguson K, Cantonwine D, Mukherjee B, Meeker J, McElrath T. Subclinical Changes in Maternal Thyroid Function Parameters in Pregnancy and Fetal Growth. The Journal Of Clinical Endocrinology & Metabolism 2017, 103: 1349-1358. PMID: 29293986, PMCID: PMC6018657, DOI: 10.1210/jc.2017-01698.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAsymptomatic DiseasesBirth WeightCase-Control StudiesFemaleFetal DevelopmentHumansInfant, NewbornPregnancyPregnancy ComplicationsPremature BirthProspective StudiesSocioeconomic FactorsThyroid DiseasesThyroid Function TestsThyroid GlandThyroid HormonesThyroxineUltrasonography, PrenatalYoung AdultConceptsBirth weight z-scoreOvert thyroid diseaseThyroid function parametersWeight z-scoreFetal growthThyroid diseaseInverse associationPregnant womenMeasurements of estimated fetal weightSubclinical changesIndices of fetal growthCase-control study of preterm birthStudy of preterm birthZ-scoreAbnormal fetal growthMaternal thyroid functionWeeks of gestationInfluence fetal growthZ-score decreaseThyroid-stimulating hormoneProspective birth cohortCase-control studyFunction parametersFetal weightPreterm birthUrinary BPA and Phthalate Metabolite Concentrations and Plasma Vitamin D Levels in Pregnant Women: A Repeated Measures Analysis
Johns L, Ferguson K, Cantonwine D, McElrath T, Mukherjee B, Meeker J. Urinary BPA and Phthalate Metabolite Concentrations and Plasma Vitamin D Levels in Pregnant Women: A Repeated Measures Analysis. Environmental Health Perspectives 2017, 125: 087026. PMID: 28934718, PMCID: PMC5783673, DOI: 10.1289/ehp1178.Peer-Reviewed Original ResearchConceptsCohort of pregnant womenMono-3-carboxypropyl phthalateVitamin D levelsPregnant womenD levelsNested case-control study of preterm birthMeasures of urinary phthalate metabolitesProspective cohort of pregnant womenOdds of vitamin D deficiencyCase-control study of preterm birthDi(2-ethylhexyl) phthalate metabolitesInverse associationStudy of preterm birthInterquartile rangePlasma vitamin D levelsCirculating total 25(OH)DNested case-control studyMetabolites of di(2-ethylhexyl) phthalateVitamin D deficiencyDi(2-ethylhexyl) phthalatePhthalate metabolite concentrationsUrinary phthalate metabolitesUrinary bisphenol AProspective birth cohortPreterm birth
2016
Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies
Ferguson K, Meeker J, McElrath T, Mukherjee B, Cantonwine D. Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies. American Journal Of Obstetrics And Gynecology 2016, 216: 527.e1-527.e9. PMID: 28043842, PMCID: PMC5420472, DOI: 10.1016/j.ajog.2016.12.174.Peer-Reviewed Original ResearchConceptsTumor necrosis factor-aNormotensive pregnanciesC-reactive proteinMeasures of inflammationHazard ratioOxidative stress biomarkersInterleukin-1bTime pointsInflammation biomarkersStudy visitsTime of preeclampsia diagnosisPrediction of preeclampsiaOxidative stressHigher body mass indexOxidative stress biomarker 8-isoprostaneStress biomarkersCox proportional hazards modelsCompared to other time pointsBody mass indexProspective birth cohortCalculate hazard ratiosSmall study populationPanel of inflammationFactor AProportional hazards model
2015
Phthalate metabolites and bisphenol-A in association with circulating angiogenic biomarkers across pregnancy
Ferguson K, McElrath T, Cantonwine D, Mukherjee B, Meeker J. Phthalate metabolites and bisphenol-A in association with circulating angiogenic biomarkers across pregnancy. Placenta 2015, 36: 699-703. PMID: 25913709, PMCID: PMC4441857, DOI: 10.1016/j.placenta.2015.04.002.Peer-Reviewed Original ResearchConceptsSFlt-1 to PlGF ratioSFlt-1Biomarkers of angiogenesisPhthalate metabolitesPlGF ratioPlacental developmentSoluble fms-like tyrosine kinase-1Fms-like tyrosine kinase-1Tyrosine kinase-1Placental growth factorUrinary DEHP metabolitesProspective birth cohortAdverse birth outcomesCase-control populationDelivered pretermGestational ageAngiogenic biomarkersExposure to phthalatesUrinary biomarkersDEHP metabolitesBirth outcomesPlasma biomarkersPregnancyPlGFAssociated with decreases
2014
Repeated measures of urinary oxidative stress biomarkers during pregnancy and preterm birth
Ferguson K, McElrath T, Chen Y, Loch-Caruso R, Mukherjee B, Meeker J. Repeated measures of urinary oxidative stress biomarkers during pregnancy and preterm birth. American Journal Of Obstetrics And Gynecology 2014, 212: 208.e1-208.e8. PMID: 25111586, PMCID: PMC4312513, DOI: 10.1016/j.ajog.2014.08.007.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPreterm birthAssociated with increased odds of spontaneous preterm birthCases of spontaneous preterm birthOdds of spontaneous preterm birthPathways to preterm birthMechanisms of preterm birthNested case-control studyLevels of 8-isoprostaneOxidative stressUrinary biomarkers of oxidative stressConcentrations of 8-isoprostaneUrinary oxidative stress biomarkersLevels of 8-OHdGMaternal oxidative stressCase-control studyProspective birth cohortUrinary 8-OHdG concentrationsAssociated with increased oddsInvestigate oxidative stressDelivered pretermBiomarkers of oxidative stressPlacental originUrinary concentrations of 8-isoprostanePreterm