2022
Occupational history associates with ALS survival and onset segment
Goutman S, Boss J, Godwin C, Mukherjee B, Feldman E, Batterman S. Occupational history associates with ALS survival and onset segment. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2022, 24: 219-229. PMID: 36193557, PMCID: PMC10067530, DOI: 10.1080/21678421.2022.2127324.Peer-Reviewed Original ResearchConceptsStandard Occupational ClassificationOccupational settingsOnset segmentSelf-reported occupational exposureAmyotrophic Lateral Sclerosis RegistrySelf-reported exposureExposure to particulate matterCervical onsetStandard Occupational Classification codesMultinomial logistic regression modelCox proportional hazards modelsLogistic regression modelsSymptom onset to diagnosisOccupational pesticide exposureProportional hazards modelAssociated with workMaintenance occupationsGrounds cleaningALS clinicALS participantsProspective cohortAdjusted modelsDiagnosis ageAmyotrophic lateral sclerosis participantsOccupational history
2012
Principal interactions analysis for repeated measures data: application to gene–gene and gene–environment interactions
Mukherjee B, Ko Y, VanderWeele T, Roy A, Park S, Chen J. Principal interactions analysis for repeated measures data: application to gene–gene and gene–environment interactions. Statistics In Medicine 2012, 31: 2531-2551. PMID: 22415818, PMCID: PMC4046647, DOI: 10.1002/sim.5315.Peer-Reviewed Original ResearchConceptsGene-environment interactionsGene-geneLongitudinal cohort studyNormative Aging StudyHealth outcomesMain effect termsMeasured outcomesAging StudyOccupational historyEpistasis modelsEnvironmental exposuresMain effectLongitudinal natureLongitudinal dataResampling-based methodsCell meansClassification arrayQuantitative traitsInteraction analysisRobust classLeading eigenvaluesSimulation studyTime-varying effectsSubject-specificOutcomes