2023
Using Multi-Modal Electronic Health Record Data for the Development and Validation of Risk Prediction Models for Long COVID Using the Super Learner Algorithm
Jin W, Hao W, Shi X, Fritsche L, Salvatore M, Admon A, Friese C, Mukherjee B. Using Multi-Modal Electronic Health Record Data for the Development and Validation of Risk Prediction Models for Long COVID Using the Super Learner Algorithm. Journal Of Clinical Medicine 2023, 12: 7313. PMID: 38068365, PMCID: PMC10707399, DOI: 10.3390/jcm12237313.Peer-Reviewed Original ResearchComposite risk scoreRisk scoreElectronic health recordsAnalyses identified several factorsValidation of risk prediction modelsModerate discriminatory abilityRisk prediction modelPost-acute sequelae of COVID-19Health recordsCombined risk scorePost-acuteIdentification of individualsPrevention effortsSuper Learner algorithmMedical recordsHealthcare challengesPublic healthMedical phenotypesCOVID-19Increased riskPredictive factorsCOVID-19 infectionRecord DataPost-acute sequelaeHigh risk
2019
High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis
Goutman S, Boss J, Patterson A, Mukherjee B, Batterman S, Feldman E. High plasma concentrations of organic pollutants negatively impact survival in amyotrophic lateral sclerosis. Journal Of Neurology Neurosurgery & Psychiatry 2019, 90: 907. PMID: 30760645, PMCID: PMC6625908, DOI: 10.1136/jnnp-2018-319785.Peer-Reviewed Original ResearchConceptsPersistent organic pollutantsPolychlorinated biphenylsHigh concentrations of persistent organic pollutantsAmyotrophic lateral sclerosisConcentrations of persistent organic pollutantsEffects of persistent organic pollutantsMeasurement of persistent organic pollutantsHazard rate of mortalitySymptom onset to diagnosisMedian diagnostic ageNegatively impacts survivalLowest quartileIndependent of ageOrganic pollutantsSummary measuresMedian timeClinical featuresMedical recordsRate of mortalityDiagnostic ageEnvironmental exposuresBulbar onsetALS diseaseCervical onsetPlasma concentrations