Testing departure from additivity in Tukey's model using shrinkage: application to a longitudinal setting
Ko Y, Mukherjee B, Smith J, Park S, Kardia S, Allison M, Vokonas P, Chen J, Diez‐Roux A. Testing departure from additivity in Tukey's model using shrinkage: application to a longitudinal setting. Statistics In Medicine 2014, 33: 5177-5191. PMID: 25112650, PMCID: PMC4227925, DOI: 10.1002/sim.6281.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAgingAtherosclerosisBone and BonesComputer SimulationEnvironmental ExposureEthnicityFemaleGene-Environment InteractionHumansIronLeadLeast-Squares AnalysisLikelihood FunctionsLongitudinal StudiesMaleMiddle AgedModels, GeneticUnited StatesUnited States Department of Veterans AffairsConceptsGene-environment interactionsMulti-Ethnic Study of AtherosclerosisModel of gene-environment interactionMulti-Ethnic StudyTukey's modelLongitudinal settingStudy of AtherosclerosisNormative Aging StudyCase-control studyIncreasing categoriesAging StudyTested interactionsLongitudinal studyCategorical variablesRobust to misspecificationInteraction termsTest departuresShrinkage estimatorsWald testInteraction estimatesIncreased powerOne-degree-of-freedom modelInteraction effectsSetsEnvironmental markers