2021
Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects
Song Y, Zhou X, Kang J, Aung M, Zhang M, Zhao W, Needham B, Kardia S, Liu Y, Meeker J, Smith J, Mukherjee B. Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects. Journal Of The Royal Statistical Society Series C (Applied Statistics) 2021, 70: 1391-1412. PMID: 34887595, PMCID: PMC8653861, DOI: 10.1111/rssc.12518.Peer-Reviewed Original ResearchNatural indirect effectMulti-Ethnic Study of AtherosclerosisMediation analysisMediator-outcome effectsMulti-Ethnic StudyStudy of AtherosclerosisCausal mediation analysisLIFECODES birth cohortBirth cohortEpidemiological studiesJoint prior distributionPotential mediatorsHigh-dimensional mediation analysisGaussian mixtureHigh-dimensional mediatorsIndirect effectsPrior distributionEstimation accuracyExposure-mediated effectsBayesian paradigmExposure effectsAvailability of measurementsComposite structuresIncreasing availability of measurementsA hierarchical integrative group least absolute shrinkage and selection operator for analyzing environmental mixtures
Boss J, Rix A, Chen Y, Narisetty N, Wu Z, Ferguson K, McElrath T, Meeker J, Mukherjee B. A hierarchical integrative group least absolute shrinkage and selection operator for analyzing environmental mixtures. Environmetrics 2021, 32 PMID: 34899005, PMCID: PMC8664243, DOI: 10.1002/env.2698.Peer-Reviewed Original ResearchGroup least absolute shrinkageEnvironmental health studiesHealth outcomesHealth StudyLIFECODES birth cohortBirth cohortExposure interactionsPenalized regression methodsDose-response relationshipExposure mixturesComprehensive R Archive NetworkInteraction effectsInduce sparsityAdaptive weightsGroup lassoSelection operatorHeredity constraintLeast Absolute ShrinkageSelection frameworkNonlinear interaction effectsSample sizeVariable selectionJoint effectsCoefficient estimatesGroup structure
2020
Urinary trace metals in association with fetal ultrasound measures during pregnancy
Kim S, Meeker J, Aung M, Yu Y, Mukherjee B, Cantonwine D, McElrath T, Ferguson K. Urinary trace metals in association with fetal ultrasound measures during pregnancy. Environmental Epidemiology 2020, 4: e075. PMID: 32201854, PMCID: PMC7083213, DOI: 10.1097/ee9.0000000000000075.Peer-Reviewed Original ResearchEstimated fetal weightBirth weightFetal weightZ-scoreAssociated with higher birth weightHead circumference z-scoreAssociated with low birth weightMeasures of fetal growthFetal ultrasound measurementsLength z-scoreLow birth weightHigh birth weightMeasured abdominal circumferenceGestational ageFetal growthAbdominal circumferenceHead circumferenceInterquartile range increaseEssential metalsLIFECODES birth cohortFemur lengthGrowth outcomesUltrasound measurementsLinear mixed effects modelsBirth cohort
2019
Manganese is associated with increased plasma interleukin-1β during pregnancy, within a mixtures analysis framework of urinary trace metals
Aung M, Meeker J, Boss J, Bakulski K, Mukherjee B, Cantonwine D, McElrath T, Ferguson K. Manganese is associated with increased plasma interleukin-1β during pregnancy, within a mixtures analysis framework of urinary trace metals. Reproductive Toxicology 2019, 93: 43-53. PMID: 31881266, PMCID: PMC7138746, DOI: 10.1016/j.reprotox.2019.12.004.Peer-Reviewed Original ResearchConceptsIL-1BBayesian kernel machine regressionKernel machine regressionInterleukin-1bInterquartile range differenceCross-sectional studyAssociated with biomarkersReproductive health outcomesImmune signaling moleculesHealth outcomesLIFECODES birth cohortPregnant womenImmune perturbationsImmune biomarkersBirth cohortUrinary manganeseMachine regressionLinear regressionExposure analytesAssociationSignaling moleculesRegressionPair-wise associationsTrimesterPregnancy
2018
Foetal ultrasound measurement imputations based on growth curves versus multiple imputation chained equation (MICE)
Ferguson K, Yu Y, Cantonwine D, McElrath T, Meeker J, Mukherjee B. Foetal ultrasound measurement imputations based on growth curves versus multiple imputation chained equation (MICE). Paediatric And Perinatal Epidemiology 2018, 32: 469-473. PMID: 30016545, PMCID: PMC6939297, DOI: 10.1111/ppe.12486.Peer-Reviewed Original ResearchConceptsLinear mixed modelsComplete-case analysisMultiple imputationEpidemiological studies of risk factorsImputed datasetsComplete-caseDemographic factorsStudy of risk factorsLIFECODES birth cohortUltrasound measurementsCalculate associationsBirth cohortCross-sectionEpidemiological studiesRisk factorsStudy visitsLongitudinal analysisParametric linear mixed modelImputationMissing dataMixed modelsLongitudinal measurementsSample sizeCovariate dataGrowth restriction
2017
Environmental phenol associations with ultrasound and delivery measures of fetal growth
Ferguson K, Meeker J, Cantonwine D, Mukherjee B, Pace G, Weller D, McElrath T. Environmental phenol associations with ultrasound and delivery measures of fetal growth. Environment International 2017, 112: 243-250. PMID: 29294443, PMCID: PMC5899051, DOI: 10.1016/j.envint.2017.12.011.Peer-Reviewed Original ResearchConceptsInverse associationBirth weight z-scoreWeight z-scoreZ-scoreFetal weightInterquartile range differenceFetal growthBirth weightUltrasound estimationUltrasound estimation of fetal weightEstimation of fetal weightLIFECODES birth cohortStandard deviation decreaseEstimated fetal weightBirth cohortOutcome measuresInvestigate sex differencesWomen's HospitalPregnant womenStudy populationStudy visitsDeviation decreaseDelivery measuresPregnancyAssociation