Maternal Metals/Metalloid Blood Levels Are Associated With Lipidomic Profiles Among Pregnant Women in Puerto Rico
Kim C, Ashrap P, Watkins D, Mukherjee B, Rosario-Pabón Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Maternal Metals/Metalloid Blood Levels Are Associated With Lipidomic Profiles Among Pregnant Women in Puerto Rico. Frontiers In Public Health 2022, 9: 754706. PMID: 35096734, PMCID: PMC8790322, DOI: 10.3389/fpubh.2021.754706.Peer-Reviewed Original ResearchConceptsAdverse birth outcomesBlood levelsPlasmenyl-phosphatidylcholinesLipidomic profilesBirth outcomesPlasmenyl phosphatidylethanolamineWeeks of pregnancyPlasma lipidomic profilesMultiple comparisonsLipid sub-classesHeavy metal exposurePolyunsaturated fatty acidsPregnant womenShotgun lipidomicsMetal exposureImportant signaling pathwaysAssessed associationsBiomarker profilesAssociated with lipidEarly detectionBirth cohortDiagnostic toolExposure to manganeseSignaling pathwayFalse discovery rate