Classification and Clustering Methods for Multiple Environmental Factors in Gene–Environment Interaction
Ko Y, Mukherjee B, Smith J, Kardia S, Allison M, Roux A. Classification and Clustering Methods for Multiple Environmental Factors in Gene–Environment Interaction. Epidemiology 2016, 27: 870-878. PMID: 27479650, PMCID: PMC5039086, DOI: 10.1097/ede.0000000000000548.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtherosclerosisBayes TheoremCluster AnalysisData Interpretation, StatisticalEnvironmental ExposureEpidemiologic Research DesignFemaleFollow-Up StudiesGene-Environment InteractionGenetic Predisposition to DiseaseHumansMiddle AgedModels, StatisticalRegression AnalysisRisk FactorsConceptsMultiple environmental exposuresGene-environment interactionsG x EEnvironmental exposuresMultiethnic Study of AtherosclerosisStudy of AtherosclerosisGene-environmentEffect modificationMultiethnic StudyEnvironmental factorsExposure subgroupsEnvironmental exposure profilesMain effectExposure profilesE studyEfficient analysis strategyE analysisMultiple environmental factorsSubgroupsAnalysis strategyFactorsExposureProduct terms