2023
Decomposing interaction and mediating effects of race/ethnicity and circulating blood levels of cystatin C on cognitive status in the United States health and retirement study
Tejera C, Ware E, Kobayashi L, Fu M, Hicken M, Zawistowski M, Mukherjee B, Bakulski K. Decomposing interaction and mediating effects of race/ethnicity and circulating blood levels of cystatin C on cognitive status in the United States health and retirement study. Frontiers In Human Neuroscience 2023, 17: 1052435. PMID: 37323925, PMCID: PMC10267311, DOI: 10.3389/fnhum.2023.1052435.Peer-Reviewed Original ResearchNon-Hispanic whitesNon-Hispanic blacksRacial disparitiesEffect of race/ethnicityDementia prevalenceRetirement StudyAssociated with dementia prevalenceExcess risk due to interactionOlder non-Hispanic WhitesRisk due to interactionNon-Hispanic white participantsHealth and Retirement StudyEstimate prevalence ratiosBehavioral risk factorsAssociated with dementiaExposure to racismModerating effect of race/ethnicityNon-white participantsStrength of associationUnited States HealthAssociated with cognitive impairmentCross-sectional sampleHispanic adultsChronic conditionsPrevalence ratios
2022
ExPRSweb: An online repository with polygenic risk scores for common health-related exposures
Ma Y, Patil S, Zhou X, Mukherjee B, Fritsche L. ExPRSweb: An online repository with polygenic risk scores for common health-related exposures. American Journal Of Human Genetics 2022, 109: 1742-1760. PMID: 36152628, PMCID: PMC9606385, DOI: 10.1016/j.ajhg.2022.09.001.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresChronic conditionsPhenome-wide association studyMichigan Genomics InitiativeRisk scoreAssociation studiesHealth-related exposuresGenome-wide association studiesUK BiobankGenetic risk factorsPRS methodsFollow-up studyRisk factorsComplex traitsGenome InitiativeGenetic modifiersBiobankInfluence of exposureEnvironmental variablesScoresLipid levelsExpRLifestyleSmokingOnline repository
2018
Associations of cumulative exposure to heavy metal mixtures with obesity and its comorbidities among U.S. adults in NHANES 2003–2014
Wang X, Mukherjee B, Park S. Associations of cumulative exposure to heavy metal mixtures with obesity and its comorbidities among U.S. adults in NHANES 2003–2014. Environment International 2018, 121: 683-694. PMID: 30316184, PMCID: PMC6268112, DOI: 10.1016/j.envint.2018.09.035.Peer-Reviewed Original ResearchConceptsEnvironmental risk scoreAssociated with obesityHeavy metal mixturesHeavy metalsMetal mixturesAssociation of cumulative exposureCumulative exposureComplex survey designEffects of cumulative exposurePhysical activityObesity measuresAdaptive elastic-netChronic conditionsExposure to heavy metalsInteraction of heavy metalsWaist circumferenceTotal body fatNHANES cyclesU.S. adultsEpidemiological researchType 2 diabetes mellitusCorrelated heavy metalSmoking statusHigher BMISkinfold thickness
2010
A new comorbidity index: the health-related quality of life comorbidity index
Mukherjee B, Ou H, Wang F, Erickson S. A new comorbidity index: the health-related quality of life comorbidity index. Journal Of Clinical Epidemiology 2010, 64: 309-319. PMID: 21147517, DOI: 10.1016/j.jclinepi.2010.01.025.Peer-Reviewed Original ResearchConceptsClinical classification codesPhysical component summaryMedical Expenditure Panel SurveyMental component summaryHealth-related qualityComponent summaryAssociated with physical component summaryHealth-related quality of life comorbidity indexShort Form-12 Physical Component SummaryMEPS databaseMeasures of HRQLComorbidity indexRisk adjustment indexChronic conditionsPanel SurveyRegression modelsInternal validityPatient populationAdjustment indicesClassification codesHRQLSummaryValidation testsIndexModel R2