2019
Application of Hybrid Matrix Metalloproteinase-Targeted and Dynamic 201Tl Single-Photon Emission Computed Tomography/Computed Tomography Imaging for Evaluation of Early Post-Myocardial Infarction Remodeling
Thorn SL, Barlow SC, Feher A, Stacy MR, Doviak H, Jacobs J, Zellars K, Renaud JM, Klein R, deKemp RA, Khakoo AY, Lee T, Spinale FG, Sinusas AJ. Application of Hybrid Matrix Metalloproteinase-Targeted and Dynamic 201Tl Single-Photon Emission Computed Tomography/Computed Tomography Imaging for Evaluation of Early Post-Myocardial Infarction Remodeling. Circulation Cardiovascular Imaging 2019, 12: e009055. PMID: 31707811, PMCID: PMC7250243, DOI: 10.1161/circimaging.119.009055.Peer-Reviewed Original ResearchConceptsMyocardial blood flowSingle photon emissionBlood flowRecombinant TIMP-3Matrix metalloproteinasesR injuryTomography/Intracoronary deliveryMMP activationPost-myocardial infarction remodelingSubsequent left ventricular remodelingHybrid single-photon emissionDual-isotope single-photon emissionTomography/Computed Tomography ImagingLeft ventricular remodelingIschemia/reperfusionPost-MI remodelingPost-myocardial infarctionComputed tomography (CT) imagingIntracoronary infusionVentricular functionSaline groupVentricular remodelingNoninvasive evaluationTreatment groups
2017
Aspirin Is Associated with Improved Survival in Severely Thrombocytopenic Cancer Patients with Acute Myocardial Infarction
Feher A, Kampaktsis PN, Parameswaran R, Stein EM, Steingart R, Gupta D. Aspirin Is Associated with Improved Survival in Severely Thrombocytopenic Cancer Patients with Acute Myocardial Infarction. The Oncologist 2017, 22: 213-221. PMID: 28159866, PMCID: PMC5330698, DOI: 10.1634/theoncologist.2016-0110.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAnti-Inflammatory Agents, Non-SteroidalAspirinFemaleHumansMaleMyocardial InfarctionNeoplasmsSurvival AnalysisThrombocytopeniaConceptsAcute myocardial infarctionThrombocytopenic cancer patientsSevere thrombocytopeniaMajor bleedingHematologic malignanciesImproved survivalMyocardial infarctionAspirin useCancer patientsPatient cohortDays of AMIGuideline-recommended medical therapyMemorial Sloan-Kettering Cancer CenterHigh-risk patient cohortTreatment of AMIBenefits of aspirinFatal bleeding eventsOverall patient cohortAspirin therapyBleeding eventsSTP patientsThienopyridine treatmentMedical therapyPlatelet countCancer Center
2015
Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention
Goyal P, Kim J, Feher A, L. C, Gurevich S, Veal DR, Szulc M, Wong FJ, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW. Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention. Coronary Artery Disease 2015, 26: 642-650. PMID: 26049923, PMCID: PMC4631658, DOI: 10.1097/mca.0000000000000271.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac-Gated Single-Photon Emission Computer-Assisted TomographyEchocardiographyExercise TestFemaleHeartHumansLogistic ModelsMaleMiddle AgedMitral Valve InsufficiencyMultivariate AnalysisMyocardial InfarctionMyocardial Perfusion ImagingPercutaneous Coronary InterventionRisk AssessmentStroke VolumeConceptsPercutaneous coronary interventionMyocardial perfusion imagingAdvanced mitral regurgitationMitral regurgitationMyocardial perfusionCoronary interventionPerfusion defectsLV volumesStress/rest myocardial perfusionLeft ventricular (LV) chamber dilationVentricular chamber dilationAbnormal myocardial perfusionMild mitral regurgitationPerfusion defect sizeIschemic mitral regurgitationMyocardial perfusion patternsRest myocardial perfusionSingle photon emissionTransthoracic echocardiographyChamber dilationPerfusion deficitsPerfusion patternsMR severityRest scorePerfusion differences