2006
Neocortical Network Activity In Vivo Is Generated through a Dynamic Balance of Excitation and Inhibition
Haider B, Duque A, Hasenstaub A, McCormick D. Neocortical Network Activity In Vivo Is Generated through a Dynamic Balance of Excitation and Inhibition. Journal Of Neuroscience 2006, 26: 4535-4545. PMID: 16641233, PMCID: PMC6674060, DOI: 10.1523/jneurosci.5297-05.2006.Peer-Reviewed Original ResearchConceptsCerebral cortexNeocortical network activityReversal potentialUp statesPersistent network activityNetwork activityDepolarized reversal potentialSpontaneous network activityField potential recordingsLocal cortical circuitsLocal field potential recordingsNeuronal responsivenessCortical functionRecurrent excitatoryCortical circuitsSynaptic currentsPotential recordingsRecurrent excitationExcitatory conductancePrefrontal cortexInhibitory connectionsCortexStable network statesSlow oscillationsInhibition
2005
Inhibitory Postsynaptic Potentials Carry Synchronized Frequency Information in Active Cortical Networks
Hasenstaub A, Shu Y, Haider B, Kraushaar U, Duque A, McCormick D. Inhibitory Postsynaptic Potentials Carry Synchronized Frequency Information in Active Cortical Networks. Neuron 2005, 47: 423-435. PMID: 16055065, DOI: 10.1016/j.neuron.2005.06.016.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsCerebral CortexCortical SynchronizationExcitatory Postsynaptic PotentialsFerretsIn Vitro TechniquesInterneuronsMaleMembrane PotentialsNerve NetNeural InhibitionNeuronsOscillometryPyramidal CellsReaction TimeRefractory Period, ElectrophysiologicalSynapsesSynaptic TransmissionConceptsInhibitory postsynaptic potentialsHigh-frequency activityPostsynaptic potentialsPyramidal cellsCortical pyramidal cellsAction potential propertiesRecurrent network activityAction potential generationActive cortical networkInhibitory interneuronsCortical functionIntracellular injectionNearby neuronsStrong barragesInhibitory networksCortical networksField potentialsSynaptic conductancesIPSPsInhibitory potentialPotential generationNetwork activitySpike timingMore synchronyVivo