2020
Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency
Bai H, Sadaghianloo N, Gorecka J, Liu S, Ono S, Ramachandra AB, Bonnet S, Mazure NM, Declemy S, Humphrey JD, Dardik A. Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency. Science Translational Medicine 2020, 12 PMID: 32817365, PMCID: PMC7705473, DOI: 10.1126/scitranslmed.aax7613.Peer-Reviewed Original ResearchConceptsArteriovenous fistulaHemodialysis accessNeointimal hyperplasiaEndothelial nitric oxide synthaseDurable surgical optionUremic male ratsRadial-cephalic arteriovenous fistulaKruppel-like factor 2Nitric oxide synthasePeak systolic velocityLong-term patencyReintervention rateSecondary patencyImproved hemodynamicsFemale patientsReimplantation techniqueSurgical optionsSystolic velocityMale ratsOxide synthaseFistula modelPatencyHemodynamicsDifferent hemodynamicsFemale animals
2008
Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study.
Nishibe T, Kondo Y, Muto A, Dardik A, Ohara Y, Kainuma M, Takeda K. Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study. The Journal Of Cardiovascular Surgery 2008, 49: 627-31. PMID: 18670380.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnalysis of VarianceAortic Aneurysm, ThoracicAortic DissectionCardiopulmonary BypassChi-Square DistributionFemaleGlycineHumansLeukocyte CountLung DiseasesMalePilot ProjectsPostoperative ComplicationsRespiratory Function TestsSerine Proteinase InhibitorsSulfonamidesTreatment OutcomeConceptsAcute aortic dissectionAortic arch surgeryPostoperative lung dysfunctionSivelestat sodiumAortic dissectionCardiopulmonary bypassWhite blood cellsProtective effectArch surgerySivelestat groupLung dysfunctionControl groupBlood cellsPostoperative lung injuryAortic arch replacementArterial oxygen tensionArch replacementAcute typeLung injuryPulmonary functionCirculatory arrestDeep hypothermiaInflammatory reactionPatientsF ratio