2021
A machine-learning approach to map landscape connectivity in Aedes aegypti with genetic and environmental data
Pless E, Saarman NP, Powell JR, Caccone A, Amatulli G. A machine-learning approach to map landscape connectivity in Aedes aegypti with genetic and environmental data. Proceedings Of The National Academy Of Sciences Of The United States Of America 2021, 118: e2003201118. PMID: 33619083, PMCID: PMC7936321, DOI: 10.1073/pnas.2003201118.Peer-Reviewed Original Research
2018
Editing nature: Local roots of global governance
Kofler N, Collins JP, Kuzma J, Marris E, Esvelt K, Nelson MP, Newhouse A, Rothschild LJ, Vigliotti VS, Semenov M, Jacobsen R, Dahlman JE, Prince S, Caccone A, Brown T, Schmitz OJ. Editing nature: Local roots of global governance. Science 2018, 362: 527-529. PMID: 30385564, DOI: 10.1126/science.aat4612.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnthozoaBioethical IssuesConservation of Natural ResourcesCoral ReefsCRISPR-Cas SystemsGene EditingGene-Environment InteractionConceptsLocal communitiesGene-editing techniquesContext-dependent impactsMost policy discussionsEcological disturbancesIsland habitatsCollective oversightClimate changeEvolutionary resistanceWild speciesLocal inputGene editingTarget mutationsSpeciesCommunityCRISPREnvironmental applicationsEcosystemsHabitatsResponsible applicationExtinctionProfound benefitsInternational levelUnprecedented capacityPolicy discussions
2016
Patterns of Genome-Wide Variation in Glossina fuscipes fuscipes Tsetse Flies from Uganda
Gloria-Soria A, Dunn WA, Telleria EL, Evans BR, Okedi L, Echodu R, Warren WC, Montague MJ, Aksoy S, Caccone A. Patterns of Genome-Wide Variation in Glossina fuscipes fuscipes Tsetse Flies from Uganda. G3: Genes, Genomes, Genetics 2016, 6: 1573-1584. PMID: 27172181, PMCID: PMC4889654, DOI: 10.1534/g3.116.027235.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChromosome MappingDNA, MitochondrialGene-Environment InteractionGenes, InsectGenetic LinkageGenetic VariationGenetics, PopulationGenome, InsectGenome-Wide Association StudyGenomicsGenotypeGeographyHigh-Throughput Nucleotide SequencingLinkage DisequilibriumMicrosatellite RepeatsPolymorphism, Single NucleotideSelection, GeneticTsetse FliesUgandaConceptsSingle nucleotide polymorphismsLinkage disequilibriumExtent of LDLocal environmental adaptationGenome-wide variationDetection of lociOverall linkage disequilibriumInsect vectorsDifferent environmental conditionsWhole-genome sequencingPopulation genomicsStrong selectionAssociation analysisEnvironmental adaptationGenomic patternsPopulation dynamicsSignificant genetic associationUninfected fliesDisease transmissionSequence technologyAssociation studiesEnvironmental conditionsTsetse fliesHuman African trypanosomiasisRelevant phenotypes