2020
Phylogeography and population structure of the tsetse fly Glossina pallidipes in Kenya and the Serengeti ecosystem
Bateta R, Saarman NP, Okeyo WA, Dion K, Johnson T, Mireji PO, Okoth S, Malele I, Murilla G, Aksoy S, Caccone A. Phylogeography and population structure of the tsetse fly Glossina pallidipes in Kenya and the Serengeti ecosystem. PLOS Neglected Tropical Diseases 2020, 14: e0007855. PMID: 32092056, PMCID: PMC7058365, DOI: 10.1371/journal.pntd.0007855.Peer-Reviewed Original Research
2017
Genetic diversity and population structure of the tsetse fly Glossina fuscipes fuscipes (Diptera: Glossinidae) in Northern Uganda: Implications for vector control
Opiro R, Saarman NP, Echodu R, Opiyo EA, Dion K, Halyard A, Dunn AW, Aksoy S, Caccone A. Genetic diversity and population structure of the tsetse fly Glossina fuscipes fuscipes (Diptera: Glossinidae) in Northern Uganda: Implications for vector control. PLOS Neglected Tropical Diseases 2017, 11: e0005485. PMID: 28453513, PMCID: PMC5425221, DOI: 10.1371/journal.pntd.0005485.Peer-Reviewed Original ResearchConceptsAnimal African trypanosomiasisGenetic clustersEffective population size estimatesLake KyogaRecent population bottleneckMitochondrial DNA markersDistinct genetic clustersPolymorphic microsatellite lociNile drainagePopulation size estimatesGenetic structurePopulation bottlenecksMain haplogroupsGenetic diversityMicrosatellite lociGenetic assignmentDNA markersPopulation structureMtDNA analysisGenetic admixtureSampling sitesGenetic unitsMost populationsTrypanosoma parasitesHuman African trypanosomiasis
2014
Analysis of Multiple Tsetse Fly Populations in Uganda Reveals Limited Diversity and Species-Specific Gut Microbiota
Aksoy E, Telleria EL, Echodu R, Wu Y, Okedi LM, Weiss BL, Aksoy S, Caccone A. Analysis of Multiple Tsetse Fly Populations in Uganda Reveals Limited Diversity and Species-Specific Gut Microbiota. Applied And Environmental Microbiology 2014, 80: 4301-4312. PMID: 24814785, PMCID: PMC4068677, DOI: 10.1128/aem.00079-14.Peer-Reviewed Original ResearchConceptsDifferent tsetse speciesRRNA gene clone librariesDifferent sympatric speciesGene clone librariesTsetse speciesLimited diversityQuantitative PCRV4 hypervariable regionGut microbiotaGut microbial abundanceSympatric speciesGut microbial diversityClone librariesMicrobial diversityMicrobial abundanceField fliesRRNA geneHost physiologyTsetse fly populationsDeep sequencingReduced diversityDifferent speciesFly populationsSpeciesWigglesworthia
2013
HUMAN IMPACTS HAVE SHAPED HISTORICAL AND RECENT EVOLUTION IN AEDES AEGYPTI, THE DENGUE AND YELLOW FEVER MOSQUITO
Brown JE, Evans BR, Zheng W, Obas V, Barrera‐Martinez L, Egizi A, Zhao H, Caccone A, Powell JR. HUMAN IMPACTS HAVE SHAPED HISTORICAL AND RECENT EVOLUTION IN AEDES AEGYPTI, THE DENGUE AND YELLOW FEVER MOSQUITO. Evolution 2013, 68: 514-525. PMID: 24111703, PMCID: PMC3946797, DOI: 10.1111/evo.12281.Peer-Reviewed Original ResearchConceptsYellow fever mosquitoSingle nucleotide polymorphism (SNP) markersHuman trade routesPatterns of domesticationArthropod disease vectorsDomestic formsNuclear genesEcological overlapEvolutionary historyDomestic AePolymorphism markersNovel nichesDNA sequencesGenetic dataEvolutionary processesDisease vectorsGenetic studiesSuch speciesLater invasionDNA sequencingNew WorldSpeciesAnthropogenic impactsHuman impactAnthropogenic forces
2012
The population structure of Glossina fuscipes fuscipes in the Lake Victoria basin in Uganda: implications for vector control
Hyseni C, Kato AB, Okedi LM, Masembe C, Ouma JO, Aksoy S, Caccone A. The population structure of Glossina fuscipes fuscipes in the Lake Victoria basin in Uganda: implications for vector control. Parasites & Vectors 2012, 5: 222. PMID: 23036153, PMCID: PMC3522534, DOI: 10.1186/1756-3305-5-222.Peer-Reviewed Original Research
2011
Unravelling the peculiarities of island life: vicariance, dispersal and the diversification of the extinct and extant giant Galápagos tortoises
POULAKAKIS N, RUSSELLO M, GEIST D, CACCONE A. Unravelling the peculiarities of island life: vicariance, dispersal and the diversification of the extinct and extant giant Galápagos tortoises. Molecular Ecology 2011, 21: 160-173. PMID: 22098061, DOI: 10.1111/j.1365-294x.2011.05370.x.Peer-Reviewed Original ResearchConceptsGiant Galápagos tortoisesHuman-mediated dispersal eventsVicariant eventsGalápagos tortoisesMainland South AmericaHuman activitiesIndependent evolutionary unitsAvailable geological dataSimple linear trendRecent human activitiesIsland lifeEvolutionary unitsEndangered taxaColonization eventsExtant speciesDispersal eventsEvolutionary historyGeological dataMultiple colonizationsExtinct speciesOcean islandsDNA dataOlder islandsYounger islandsOceanic islandsInfluence of Host Phylogeographic Patterns and Incomplete Lineage Sorting on Within-Species Genetic Variability in Wigglesworthia Species, Obligate Symbionts of Tsetse Flies
Symula RE, Marpuri I, Bjornson RD, Okedi L, Beadell J, Alam U, Aksoy S, Caccone A. Influence of Host Phylogeographic Patterns and Incomplete Lineage Sorting on Within-Species Genetic Variability in Wigglesworthia Species, Obligate Symbionts of Tsetse Flies. Applied And Environmental Microbiology 2011, 77: 8400-8408. PMID: 21948847, PMCID: PMC3233068, DOI: 10.1128/aem.05688-11.Peer-Reviewed Original ResearchConceptsObligate symbiontsHost speciesGenetic variationMultiple host populationsIncongruence length difference testIncomplete lineage sortingHost-symbiont combinationsSingle host speciesPopulation-level processesIncomplete lineageLineage sortingPhylogeographic patternsSouthern lineagesSymbiont lineagesHost mtDNAWigglesworthia glossinidiaMolecular varianceBacterial symbiontsEvolutionary associationEvolutionary historySouthern populationsMitochondrial DNA haplogroupsVariable lociSymbiontsGenetic variabilityPhylogeography and Taxonomy of Trypanosoma brucei
Balmer O, Beadell J, Gibson W, Caccone A. Phylogeography and Taxonomy of Trypanosoma brucei. PLOS Neglected Tropical Diseases 2011, 5: e961. PMID: 21347445, PMCID: PMC3035665, DOI: 10.1371/journal.pntd.0000961.Peer-Reviewed Original Research
2010
Population Genetic Structure of Aldabra Giant Tortoises
Balmer O, Ciofi C, Galbraith D, Swingland I, Zug G, Caccone A. Population Genetic Structure of Aldabra Giant Tortoises. Journal Of Heredity 2010, 102: 29-37. PMID: 20805288, DOI: 10.1093/jhered/esq096.Peer-Reviewed Original ResearchConceptsGenetic structurePopulation structureGiant tortoisesMitochondrial DNA control region sequencesPopulation genetic structureSignificant population structureControl region sequencesAldabra giant tortoisePrevious ecological studiesAllopatric divergenceNuclear lociPopulation subdivisionHabitat variationMtDNA sequencesMicrosatellite lociPopulation geneticsUnsuitable habitatGenetic variabilityAllelic variationRegion sequencesEcological factorsTerrestrial ecosystemsPopulation dynamicsAldabra AtollGeographical barriersInference of Population History by Coupling Exploratory and Model-Driven Phylogeographic Analyses
Garrick R, Caccone A, Sunnucks P. Inference of Population History by Coupling Exploratory and Model-Driven Phylogeographic Analyses. International Journal Of Molecular Sciences 2010, 11: 1190-1227. PMID: 20480016, PMCID: PMC2871112, DOI: 10.3390/ijms11041190.Peer-Reviewed Original ResearchMeSH KeywordsGene FrequencyGenealogy and HeraldryGenetic VariationGenotypeModels, GeneticPhylogeographyPopulation DensityConceptsPhylogeographic analysisGene treesGenetic diversityConservation managementPopulation historyDNA sequencesGenetic datasetsGenetic dataCladistic analysisHistorical inferencesPopulation processesTemporal concordanceSynergistic interactionDiversitySpeciationSpatial distributionSequenceGeographic contextTrees