Study: People Who Regularly Drink Alcohol Could Be More Prone to Internet, Gaming, and Exercise Addiction
An international research team with members that include Yale scientist Marc Potenza, MD, PhD, have identified several genes and their variants that trigger both substance use and other potentially addictive behaviors.
Epidemiologic and Genetic Associations of Endometriosis With Depression, Anxiety, and Eating Disorders
A Yale-led study published in JAMA Network Open is the first large-scale analysis to investigate phenotypic and genetic factors contributing to the psychiatric comorbidity of endometriosis, a complex gynecologic disease.
Cannabis Use is Associated With Low Plasma Endocannabinoid Anandamide in Individuals With Psychosis
Anahita Bassir Nia, MD, assistant professor of psychiatry, and Claire Gibson, MD, fourth-year resident, are lead and contributing authors, respectively, of a study in Journal of Psychopharmacology reporting that among individuals with psychosis, cannabis use is associated with lower levels of Anandamide, one of the main endogenous cannabinoids. This is the first published study on the peripheral levels of endocannabinoids in individuals with psychosis.Source: Journal of Psychopharmacology
Can Neuroimaging Reveal the Roots of Psychiatric Disorders? Not Just Yet
Neuroimaging technology has been shown to hold great promise in helping clinicians link specific symptoms of mental health disorders to abnormal patterns of brain activity. But a new Yale-led study shows there are still kinks to be ironed out before doctors can translate images of the brain to psychiatric disorders such as post-traumatic stress disorder (PTSD).Source: Yale News
Confronting Racially Exclusionary Practices in the Acquisition and Analyses of Neuroimaging Data
A new paper by Yale School of Medicine researchers challenges scientists in the global neuroscience community to create a more diverse representation of study participants through improved recruitment and enhanced methodological and analysis practices.
Newly Identified Neuromarker Reveals Clues About Drug and Food Craving
Hedy Kober, PhD, associate professor of psychiatry and psychology, is senior author of a study published in Nature Neuroscience that uncovered a pattern of brain activity that predicts drug and food craving, a potentially valuable biomarker for addiction.Source: Yale News
Krystal Research Published in The Lancet
Data from an early phase clinical trial of a drug being developed for adults living with schizophrenia was published December 15 in The Lancet. John H. Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and professor of psychiatry, of neuroscience, and of psychology, and chair of the Yale Department of Psychiatry, is first author of the study of the drug emraclidine, developed by Cerevel Therapeutics.
Yale Department of Internal Medicine Celebrates Top Female Scientists
Last month, Research.com published the Best Female Scientists in 2022. The results were based on a ranking system which measures the impact of a researcher’s publications by combining the number of papers they have published and how often they are cited by other papers. 623 U.S.-based researchers appeared in list with three women representing the Yale Department of Internal Medicine.
Yale Study Seeks to Understand Neurobiology Underlying Bipolar Disorder Vs. Major Depressive Disorder
Yale scientists, including Sophie Holmes, PhD; Ruth Asch, PhD; and Irina Esterlis, PhD, used positron emission tomography to understand the neurobiology underlying bipolar disorder versus major depressive disorder. The findings were published in Biological Psychiatry.Source: Biological Psychiatry
Collaboration on NIH grant between Sullivan, Nez Henderson will create program to help Indigenous women experiencing domestic violence quit smoking
Tami Sullivan, PhD, associate professor of psychiatry at Yale School of Medicine, and Patricia Nez Henderson, MD, MPH, vice president for the Black Hills Center for American Indian Health (BHCAIH) and the first Indigenous woman to graduate from Yale School of Medicine, have been awarded a grant from the National Institutes of Health (NIH) to pilot a mindfulness-based, culturally-tailored smoking cessation intervention for Indigenous women who experience intimate partner violence (IPV).
A Randomized Clinical Trial to Evaluate an Atrial Fibrillation Stroke Prevention Shared Decision‐Making Pathway
Oral anticoagulation (OAC) reduces stroke and disability in atrial fibrillation (AF) but is underutilized. Researchers, including Julio Nunes, MD, first-year resident, evaluated the effects of a novel patient‐clinician shared decision‐making (SDM) tool in reducing OAC patient's decisional conflict as compared to usual care.Source: Journal of the American Heart Association
Does Street Outreach Engage Its Intended Target Population? Clinical Experience in the Veteran’s Health Administration Homeless Service Programs
Emma Lo, MD; Jack Tsai, PhD; Elina Stefanovics, PhD; and Robert Rosenheck, MD, are co-authors of a paper in Psychiatric Quarterly that found veterans engaged through clinical street outreach programs reported substantially more days of unsheltered homelessness than a clinic-referred group of veterans.Source: Psychiatric Quarterly
Yale Study Revises Understanding of How the Brain Processes and Responds to Rewards
A new Yale study of neuron activity in the brain has revised scientists’ understanding of how the brain processes and responds to rewards. Marina Picciotto, PhD, Charles B. G. Murphy Professor of Psychiatry and Professor in the Child Study Center, of Neuroscience and of Pharmacology, is the study’s senior author.
Moderating the Relationship Between Ulcerative Colitis and Crohn’s Disease and Symptoms of PTSD
Alexandra Fuss, PhD, assistant professor of psychiatry, is first author of a paper in Journal of Clinical Gastroenterology that examines whether inflammatory bowel disease (IBD) patients endorse clinically significant symptoms of post-traumatic stress disorder (PTSD), and tests whether remission status and remission expectations effectively moderate the relationship between endorsements of PTSD symptoms and aspects of IBD.Source: Journal of Clinical Gastroenterology
Ketamine infusions improve symptoms of depression, anxiety and suicidal ideation, study says
People who got intravenous ketamine at three private ketamine infusion clinics had "significant improvement" in symptoms of depression, anxiety and suicidal ideation, according to a new study by Gerard Sanacora, PhD, MD George D. and Esther S. Gross Professor of Psychiatry, published in the Journal of Clinical Psychiatry.Source: CNN
De Aquino Awarded IMPOWR-YOU Grant to Study Pain Sensitivity, Opioid Use Disorder
Joao P. De Aquino, MD, assistant professor of psychiatry, has been awarded a pilot grant from the Integrative Management of Chronic Pain and Opioid Use Disorder for Whole Recovery-Yale and Organizations United (IMPOWR-YOU) Research Center to evaluate the relationship between pain sensitivity and brain synaptic density among people with opioid use disorder (OUD).