Justin "Jay" Bader, MD
Hospital ResidentCards
About
Research
Publications
2026
Prognostic impact of somatic mutations among patients with pleural and peritoneal mesothelioma
Bader JM, Dhiman A, Aguirre N, Ofori KA, Gupta P, Qin H, Sharma A, Mitchell O, Tjota MY, Husain AN, Drazer M, Churpek J, Kindler H, Turaga K. Prognostic impact of somatic mutations among patients with pleural and peritoneal mesothelioma. Npj Precision Oncology 2026 DOI: 10.1038/s41698-026-01495-x.Peer-Reviewed Original ResearchThis study investigates the prognostic impact of somatic mutations in mesothelioma, showing NF2 truncating variants worsen survival, supporting genomic testing to guide treatment strategies.A Personalized Prediction Model for Postcontrast Acute Kidney Injury After Peripheral Vascular Intervention
Phu T, Wang C, Bader J, Huang Y, Slade M, Aboian E, Zwibelman H, Cardella J, Guzman R, Chaar C. A Personalized Prediction Model for Postcontrast Acute Kidney Injury After Peripheral Vascular Intervention. Journal Of Vascular Surgery 2026, 84: e161-e162. DOI: 10.1016/j.jvs.2026.03.244.Peer-Reviewed Original ResearchPeritoneal Metastases in Stage II–III Colon Cancer Represent a Blind Spot for Circulating Tumor DNA Surveillance
Ofori K, Smart H, Liu S, Bader J, Aguirre N, Gupta P, Sharma A, Turaga K. Peritoneal Metastases in Stage II–III Colon Cancer Represent a Blind Spot for Circulating Tumor DNA Surveillance. Annals Of Surgical Oncology 2026, 1-4. PMID: 42265516, DOI: 10.1245/s10434-026-19903-8.Peer-Reviewed Original ResearchCirculating tumor DNAStage II-III colon cancerPeritoneal metastasisColon cancerCirculating tumor DNA studiesCirculating tumor DNA levelsHigh-risk patientsTumor sheddingAdjuvant therapyTumor DNAClinical dataMetastasisSecondary analysisPatientsCancerDNA surveillanceSurveillanceRecurrenceTumorTherapyAdjuvantAssociations of autoimmune diseases with appendiceal cancer in a population-based study.
Ofori K, Bader J, Reddy B, Aguirre N, Gupta P, Sharma A, Godfrey E, Ong C, Cecchini M, Sundar R, Turaga K. Associations of autoimmune diseases with appendiceal cancer in a population-based study. Journal Of Clinical Oncology 2026, 44: e16495-e16495. DOI: 10.1200/jco.2026.44.16_suppl.e16495.Peer-Reviewed Original ResearchElectronic health recordsPopulation-based studyCancer-free controlsHealth recordsCausal pathwaysOdds ratioUs Research ProgramSex-adjusted analysesSex-adjusted modelsType 1 diabetesInflammatory bowel diseaseP-valueNo historyAdjusted ORCancer casesICD codesU.S. cohortRheumatoid arthritisAdult participantsLogistic regressionAppendiceal cancerBenign thyroid disordersAutoimmune thyroid diseaseHighest prevalenceThyroid disordersNatural history, treatment, survival, and causes of mortality in patients with subsolid and ground-glass nodules
Bader J, Prince S, de Santis W, Kane E, Tanoue L, Bader A, Blasberg J, Detterbeck F, Woodard G. Natural history, treatment, survival, and causes of mortality in patients with subsolid and ground-glass nodules. Chest 2026 PMID: 42155700, DOI: 10.1016/j.chest.2026.04.053.Peer-Reviewed Original ResearchGround-glass opacitiesPart-solid nodulesSubsolid nodulesChest CT scanNonsolid nodulesCT scanNatural historyNatural history of growthFive-year overall survivalSubtypes of lung adenocarcinomaYears of follow-upMultiple lung nodulesComprehensive cohort of patientsOutcomes of patientsCohort of patientsGround-glass nodulesComprehensive cohortLikelihood of treatmentOverall survivalPrimary malignancyPrimary cancerChart reviewManual chart reviewClinical decision-makingFollow-upRadiographic Tumor Regression as a Predictor for Pathologic Response after Neoadjuvant Therapy for Non-Small Cell Lung Cancer
Bader J, Ermer T, de Santis W, Ragoowansi H, Kramer R, Zolfaghari E, Tremblay E, Resio B, Boffa D, Blasberg J, Bader A, Dacic S, Woodard G. Radiographic Tumor Regression as a Predictor for Pathologic Response after Neoadjuvant Therapy for Non-Small Cell Lung Cancer. JTCVS Open 2026, 101831. DOI: 10.1016/j.xjon.2026.101831.Peer-Reviewed Original ResearchPathological complete responseNon-small cell lung cancerNeoadjuvant therapyCell lung cancerPathological responseViable tumorTumor sizeLung cancerPathologic response to neoadjuvant therapyPatients treated with neoadjuvant therapyAssociated with pathologic complete responseResponse to neoadjuvant therapyPD-L1 statusPersistent viable tumorRadiographic tumor regressionRadiographic tumor responseRadiographic tumor sizeResidual viable tumorLong-term outcomesPET SUVmaxSUVmax decreaseComplete responseNeoadjuvant treatmentRadiographic responsePD-L1CEACAM5 as a biomarker of semi-solid, lepidic lung adenocarcinoma
Bader J, de Santis W, Kane E, Jaiswal A, Cho C, Kidacki M, Chen L, Dacic S, Woodard G. CEACAM5 as a biomarker of semi-solid, lepidic lung adenocarcinoma. Translational Lung Cancer Research 2026, 15: 131-131. PMID: 42291360, PMCID: PMC13263804, DOI: 10.21037/tlcr-2026-1-0102.Peer-Reviewed Original ResearchNon-small cell lung cancerGround-glass opacitiesSolid non-small cell lung cancerCarcinoembryonic antigen-related cell adhesion molecule 5H-scoreLung cancerLung adenocarcinomaClinical Laboratory Improvement AmendmentsCell carcinomaLepidic adenocarcinomaRadiographic evolutionClinical historySurgically resected non-small cell lung cancerCarcinoembryonic antigenCD8+ T cellsSubtype of non-small cell lung cancerCEACAM5 expressionStage I adenocarcinomaB cell infiltrationInvasive lung cancerSquamous cell carcinomaCell lung cancerEarly detectionResistance to apoptosisStage adenocarcinomaEvolving therapeutics in colorectal cancer peritoneal metastases
Bader J, Aguirre N, Schultz K, Ofori K, Godfrey E, Gupta P, Tseng R, Cecchini M, Sundar R, Turaga K. Evolving therapeutics in colorectal cancer peritoneal metastases. Cancer And Metastasis Reviews 2026, 45: 25. PMID: 42024175, DOI: 10.1007/s10555-026-10335-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHyperthermic intraperitoneal chemotherapyColorectal cancer peritoneal metastasesCytoreductive surgeryPeritoneal metastasisClinical trialsLandmark clinical trialsIntraperitoneal chemotherapySystemic therapyCRC-PMTherapeutic challengeDiagnostic challengeGuideline recommendationsTherapeutic approachesTreatment approachesMetastasisTrialsChemotherapySurgeryTherapyASO Author Reflections: New Insights for Personalized HIPEC Strategies in Colorectal Cancer Peritoneal Metastases
Gupta P, Godfrey E, Schultz K, Qiao L, Aguirre N, Bader J, Foote M, Shen J, Shergill A, Cecchini M, Sundar R, Sheltzer J, Turaga K. ASO Author Reflections: New Insights for Personalized HIPEC Strategies in Colorectal Cancer Peritoneal Metastases. Annals Of Surgical Oncology 2026, 33: 6194-6195. PMID: 41896510, DOI: 10.1245/s10434-026-19312-x.Peer-Reviewed Original ResearchPIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma
Gupta P, Gujarathi R, Qiao L, Godfrey E, Schultz K, Butensky S, Bader J, Sundar R, Cecchini M, Shergill A, Sheltzer J, Turaga K. PIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma. JCO Precision Oncology 2026, 10: e2500741. PMID: 41712872, DOI: 10.1200/po-25-00741.Peer-Reviewed Original ResearchThis study investigates PIK3CA mutations in early-onset appendiceal adenocarcinoma, showing their higher prevalence and association with worse survival, suggesting potential for targeted therapies.
Clinical Trials
Current Trials
A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis
IRB ID2000038133RoleSub InvestigatorPrimary Completion Date02/15/2027Recruiting Participants
Academic Achievements & Community Involvement
News
News
- April 27, 2026
Personalized Chemotherapy for Abdominal Cancer: A Q&A with Kiran Turaga
- March 09, 2026
Yale Cancer Center Experts Present Advances in Cancer Research at Major Surgical Meeting
- October 14, 2025
Showcasing the Beauty of Basic Science
- February 05, 2024
Surgical Education Solutions: Grant Recipients Announced
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