Yale Tobacco Center of Regulatory Science

In 2009, the Family Smoking Prevention and Tobacco Control Act (Tobacco Control Act) was passed which gave the U.S. Food and Drug Administration (FDA) the authority to regulate the manufacture, distribution, and marketing of tobacco products to protect public health. With the passage of the Tobacco Control Act, NIH and the FDA formed an interagency partnership to foster tobacco regulatory research. At the center of this association is the funding of 14 Tobacco Centers of Regulatory Science (TCORS), made up of scientists with a broad range of expertise develop science-based policies to reduce addiction to tobacco products.

The Yale Tobacco Center of Regulatory Science (TCORS) conducts programmatic research to examine the influence of flavors, and related factors, on preference for and addiction to tobacco products. With the overarching goal of reducing addiction to tobacco products, the Yale TCORS will conduct detailed evaluations of the influence of flavors and sweeteners on the addictive potential of tobacco products. Cohesive and hypothesis driven, our research incorporates multiple methods and disciplines. The multidisciplinary team includes experts in sensory perception, tobacco addiction, adolescent tobacco use, menthol and irritant receptor biology, nicotinic receptor biology, dopaminergic signaling in brain reward pathways, human behavioral pharmacology, assay and clinical pharmacokinetics of drugs of abuse, analytical chemistry, health economics and decision making science, and tobacco regulation.

In addition, the center trains scientists, and provides pilot funding to stimulate research related to tobacco regulatory science.

Get Involved

Learn how you can participate in research studies sponsored by Yale TCORS investigators. Please contact the Center's office at 203-974-7591 or email tcors@yale.edu for more information.

The Yale Tobacco Center of Regulatory Science (TCORS) is offering funding for pilot projects to initiate research relating to understanding tobacco additives and modified risk tobacco products.

Message to e-cigarette researchers

E-cigarette researchers: You may need to get FDA approval for the use of the e-cigarette as an investigational tobacco product. At this link, the FDA outlines the proposed requirements for obtaining an ITP for all federally funded e-cigarette research. If you have any further questions please contact us.