Neha Arun
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Biography
I am a Microbiology PhD student in the lab of Dr. Walther Mothes investigating antibody Fc-effector functions against HIV-1 through structural and functional approaches, including flow virometry. My research is driven by a commitment to develop accessible antiviral strategies by interrogating the virus-host interface.
I graduated Summa Cum Laude in May 2023 as a University of Illinois Urbana-Champaign Stamps Scholar, with a BS in Molecular & Cellular Biology (MCB). I was awarded Highest Distinction and Academic Distinction in MCB for my senior thesis on “Structural and biochemical mechanisms of HIV latency reactivation in monocytes, macrophages, and T-cells” in the laboratory of Dr. Collin Kieffer.
Last Updated on January 29, 2026.
Departments & Organizations
Education & Training
- BS
- University of Illinois Urbana-Champaign, Molecular and Cellular Biology
- Dr. Walter A. and Loretta M. Zygmunt Microbiology Scholar
- University of Illinois Urbana-Champaign (2022)
- Summer Undergraduate Research Fellow
- Mayo Clinic (2021)
- School of MCB Summer Undergraduate Research Fellow
- University of Illinois Urbana-Champaign (2020)
Research
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Overview
Medical Research Interests
Antibody-Dependent Cell Cytotoxicity; Cryoelectron Microscopy; HIV; HIV Antibodies; HIV-1; Receptors, Fc
ORCID
0009-0005-0111-2973- View Lab Website
Mothes Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Neha Arun's published research.
Esen Sefik, PhD
Haris Mirza, MBBS, PhD
Michael Chiorazzi, MD, PhD
Richard Flavell, PhD, FRS
Stephanie Halene, MD, Dr Med
William Philbrick, PhD
Publications
2025
Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow
Sefik E, Philbrick W, Zhang F, Agrawal K, Van Lee B, Sam J, Karatepe K, Zheng Y, Liang K, Peng S, Mirza H, Rangavajhula A, Simon P, Arun N, Babu P, Eynon E, Chiorazzi M, Shan L, Halene S, Luo H, Rongvaux A, Kluger Y, Flavell R. Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2426546122. PMID: 40956886, PMCID: PMC12478129, DOI: 10.1073/pnas.2426546122.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsBone marrowHuman CD47Human granulocyte-macrophage progenitorsHuman immune developmentMature human monocytesHuman neutrophilsHumanized mouse modelNeutrophil extracellular trap formationHuman hematopoietic stemGranulocyte-macrophage progenitorsHuman M-CSFHuman immune responseGenetically modified miceResponse to inflammationExtracellular trap formationHuman bone marrowCD47 promoterHuman immune systemPhysiological levelsNK cellsHumanized miceDendritic cellsHematopoietic stemMyeloid lineageHuman hematopoiesis
2024
Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation.
Blanco A, Coronado RA, Arun N, Ma K, Dar RD, Kieffer C. Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation. Proc Natl Acad Sci U S A 2024, 121: e2313823121. PMID: 38683980, DOI: 10.1073/pnas.2313823121.Peer-Reviewed Original Research
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Apr 20262Thursday
Yale Only Allison Didychuk, PhD