Mauro Giuffrè, MD
Postdoctoral FellowDownloadHi-Res Photo
About
Titles
Postdoctoral Fellow
Biography
Dr. Mauro Giuffrè is a Postdoctoral Associate at the Yale School of Medicine's Division of Internal Medicine. After earning his medical degree cum laude from the University of Trieste in Italy, he obtained a Master's in Biostatistics for Clinical Research from the University of Padova in 2019. That same year, he began his fellowship in Gastroenterology and Hepatology at the University of Trieste.
Dr. Giuffrè's primary focus in the past years has been related to the use of machine learning techniques to predict complications in advanced chronic liver disease through non-invasive techniques. His research has been published in numerous peer-reviewed journals and presented at international conferences, including the American Association for the Study of Liver Diseases (AASLD), European Association for the Study of the Liver (EASL), Italian Association for the Study of the Liver (AISF), and the Italian Federation for Gastrointestinal Disease Societies (FISMAD).
Dr. Giuffrè is currently working as a Postdoctoral Associate at the Human+Artificial Intelligence in Medicine (HAIM) Laboratory, focusing on the safe and accurate implementation of Large Language Models in clinical practice.
Appointments
Departments & Organizations
Education & Training
- Gastroenterology and Hepatology Fellowship
- University of Trieste (Italy) (2023)
- Master's in Biostatistic for Clinical Research
- University of Padova (Italy) (2019)
- MD
- University of Trieste (Italy), Department of Medicine, Surgery and Health Sciences (2018)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Mauro Giuffrè's published research.
Publications Timeline
A big-picture view of Mauro Giuffrè's research output by year.
Dennis Shung, MD, MHS, PhD
44Publications
113Citations
Publications
2024
Predicting response to non-selective beta-blockers with liver–spleen stiffness and heart rate in patients with liver cirrhosis and high-risk varices
Giuffrè M, Dupont J, Visintin A, Masutti F, Monica F, You K, Shung D, Crocè L. Predicting response to non-selective beta-blockers with liver–spleen stiffness and heart rate in patients with liver cirrhosis and high-risk varices. Hepatology International 2024, 1-12. PMID: 38664292, DOI: 10.1007/s12072-024-10649-7.Peer-Reviewed Original ResearchConceptsHigh-risk varicesHepatic venous pressure gradientLiver stiffnessLiver cirrhosisSpleen stiffnessVariceal gradeHeart rateCohort of cirrhotic patientsNon-selective beta-blockersPercentual decreaseAssessed therapeutic responseMultivariate modelVenous pressure gradientCut-off valueOptimal cut-offAssociated with better predictionNSBB treatmentPrimary prophylaxisHemorrhagic episodesCirrhotic patientsTherapeutic responseBeta-blockersNSBBTreatment initiationProspective studyOptimization of hepatological clinical guidelines interpretation by large language models: a retrieval augmented generation-based framework
Kresevic S, Giuffrè M, Ajcevic M, Accardo A, Crocè L, Shung D. Optimization of hepatological clinical guidelines interpretation by large language models: a retrieval augmented generation-based framework. Npj Digital Medicine 2024, 7: 102. PMID: 38654102, PMCID: PMC11039454, DOI: 10.1038/s41746-024-01091-y.Peer-Reviewed Original ResearchCitationsAltmetricConceptsClinical decision support systemsFew-shot learningLanguage modelImprove clinical decision support systemsDecision support systemText similarity scoresText similarityAblation studiesImprove overall accuracyGeneration accuracyRight informationAccurate outputSupport systemTransform healthcareIncreasing levels of complexityHospital workflowOverall accuracyRight providerTurbo modelLearning strategiesLevel of complexityLearningRetrievalCorpus of textsAccuracyClostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options.
Di Bella S, Sanson G, Monticelli J, Zerbato V, Principe L, Giuffrè M, Pipitone G, Luzzati R. Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options. Clin Microbiol Rev 2024, e0013523. PMID: 38421181, DOI: 10.1128/cmr.00135-23.Peer-Reviewed Original ResearchScrutinizing ChatGPT Applications in Gastroenterology: A Call for Methodological Rigor to Define Accuracy and Preserve Privacy
Giuffrè M, Shung D. Scrutinizing ChatGPT Applications in Gastroenterology: A Call for Methodological Rigor to Define Accuracy and Preserve Privacy. Clinical Gastroenterology And Hepatology 2024, 22: 2156-2157. PMID: 38311148, DOI: 10.1016/j.cgh.2024.01.024.Peer-Reviewed Original ResearchCitationsConcepts
2023
Evaluating ChatGPT in Medical Contexts: The Imperative to Guard Against Hallucinations and Partial Accuracies
Giuffrè M, You K, Shung D. Evaluating ChatGPT in Medical Contexts: The Imperative to Guard Against Hallucinations and Partial Accuracies. Clinical Gastroenterology And Hepatology 2023, 22: 1145-1146. PMID: 37863408, DOI: 10.1016/j.cgh.2023.09.035.Peer-Reviewed Original ResearchCitationsAltmetricHarnessing the power of synthetic data in healthcare: innovation, application, and privacy
Giuffrè M, Shung D. Harnessing the power of synthetic data in healthcare: innovation, application, and privacy. Npj Digital Medicine 2023, 6: 186. PMID: 37813960, PMCID: PMC10562365, DOI: 10.1038/s41746-023-00927-3.Peer-Reviewed Original ResearchCitationsAltmetricConceptsDifferential privacySynthetic dataPredictive analyticsReal-world healthcare applicationDigital twin technologyData privacyData integrityPrivacy concernsTwin technologyData misuseHealthcare applicationsPrivacyData biasDifferent applicationsData qualityAnalyticsAlgorithmic tradingAnalytic contextApplicationsHealthcareTraceabilityDatasetEmergent fieldPropose strategiesPortfolio optimizationPylephlebitis: A Systematic Review on Etiology, Diagnosis, and Treatment of Infective Portal Vein Thrombosis.
Fusaro L, Di Bella S, Martingano P, Crocè LS, Giuffrè M. Pylephlebitis: A Systematic Review on Etiology, Diagnosis, and Treatment of Infective Portal Vein Thrombosis. Diagnostics (Basel) 2023, 13 PMID: 36766534, DOI: 10.3390/diagnostics13030429.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation.
Giuffrè M, Gazzin S, Zoratti C, Llido JP, Lanza G, Tiribelli C, Moretti R. Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation. Int J Mol Sci 2022, 23 PMID: 36555205, DOI: 10.3390/ijms232415564.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsIncisional hernia by liver cysts.
Giuffrè M, Budel M, Martingano P, Crocè LS. Incisional hernia by liver cysts. Clin Case Rep 2022, 10: e6491. PMID: 36381054, DOI: 10.1002/ccr3.6491.Peer-Reviewed Case Reports and Technical NotesPredictors of Hepatocellular Carcinoma Early Recurrence in Patients Treated with Surgical Resection or Ablation Treatment: A Single-Center Experience.
Giuffrè M, Zuliani E, Visintin A, Tarchi P, Martingano P, Pizzolato R, Bonazza D, Masutti F, Moretti R, Crocè LS, Liver Multidisciplinary Group of Trieste. Predictors of Hepatocellular Carcinoma Early Recurrence in Patients Treated with Surgical Resection or Ablation Treatment: A Single-Center Experience. Diagnostics (Basel) 2022, 12 PMID: 36292205, DOI: 10.3390/diagnostics12102517.Peer-Reviewed Original Research