George Chen
Clinical FellowAbout
Research
Publications
2024
Inpatient management of bacterial infections in patients with cirrhosis: A clinical review
Chen G, To U. Inpatient management of bacterial infections in patients with cirrhosis: A clinical review. Clinical Liver Disease 2024, 23: e0214. PMID: 38952696, PMCID: PMC11216674, DOI: 10.1097/cld.0000000000000214.Peer-Reviewed Original ResearchClinical and socioeconomic determinants of survival in biliary tract adenocarcinomas
Sahyoun L, Chen K, Tsay C, Chen G, Protiva P. Clinical and socioeconomic determinants of survival in biliary tract adenocarcinomas. World Journal Of Gastrointestinal Oncology 2024, 16: 1374-1383. PMID: 38660666, PMCID: PMC11037051, DOI: 10.4251/wjgo.v16.i4.1374.Peer-Reviewed Original ResearchSocioeconomic statusPercentage of foreign-born personsHigher incomeSignificance of socioeconomic statusLow-income countiesCollege level educationCox proportional hazards modelsUrban populationAssociated with higher survival ratesForeign-born personsProportional hazards modelCancer survivalSocioeconomic determinantsEducation levelLevel educationHousehold incomeSocioeconomic dataPoverty levelPercentage of patientsHazards modelEnd Results databaseRace/ethnicitySurvival outcomesCountyResults database
2023
Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Chen G, Banini B, Do A, Gunderson C, Zaman S, Lim J. Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Genes 2023, 14: 1811. PMID: 37761951, PMCID: PMC10531443, DOI: 10.3390/genes14091811.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseBiopsy-proven non-alcoholic fatty liver diseaseEffects of exerciseFatty liver diseaseHistological outcomesLiver histologyLiver diseaseClinical trialsHistological endpointsSystematic reviewSignificant histopathological improvementNAFLD activity scoreImpact of exerciseIndependent effectsRandom-effects modelSystematic literature searchHistopathological improvementExercise interventionActivity scoreClinical endpointsPooled estimatesMeta-AnalysisTotal participantsLiterature searchComparison groupAppendiceal adenocarcinoma is associated with better prognosis than cecal adenocarcinoma: a population-based comparative survival study
Chen G, Chen K, Sahyoun L, Zaman S, Protiva P. Appendiceal adenocarcinoma is associated with better prognosis than cecal adenocarcinoma: a population-based comparative survival study. BMJ Open Gastroenterology 2023, 10: e001045. PMID: 36822658, PMCID: PMC9950880, DOI: 10.1136/bmjgast-2022-001045.Peer-Reviewed Original ResearchConceptsCecal adenocarcinomaAppendiceal adenocarcinomaCox regression analysisAppendiceal cancerMantel-Haenszel log-rank testColorectal cancer screening ratesMultivariable Cox regression analysisCounty-level socioeconomic factorsCancer screening ratesEnd Results (SEER) databaseKaplan-Meier methodRare gastrointestinal malignancyLog-rank testNon-mucinous histologySingle marital statusNon-Hispanic ethnicityYears of ageComparative survival analysisComparative survival studyRegression analysisSAS V.9.4Gastrointestinal malignanciesOverall survivalBetter prognosisChemotherapy protocols
2022
The Independent Effect of Exercise on Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review
Chen G, Banini B, Do A, Lim J. The Independent Effect of Exercise on Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review. Clinical And Molecular Hepatology 2022, 29: s319-s332. PMID: 36517000, PMCID: PMC10029942, DOI: 10.3350/cmh.2022.0366.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseBiopsy-proven non-alcoholic fatty liver diseaseNon-invasive testsFatty liver diseaseHepatic steatosisLiver fibrosisLiver diseaseHistological endpointsIndependent effectsSystematic reviewNon-randomized interventional studyMagnetic resonance imaging-based techniquesAdditional large RCTsChronic liver diseaseSignificant histological improvementEffects of exerciseClinical outcome endpointsSystematic literature searchHistological improvementExercise interventionHepatocyte ballooningOriginal research studiesLarge RCTsOutcome endpointsInterventional study
2021
Improving Medical Student Clinical Knowledge and Skills Through Influenza Education.
Chen G, Kazmi M, Chen D, Phillips J. Improving Medical Student Clinical Knowledge and Skills Through Influenza Education. Med Sci Educ 2021, 31: 1645-1651. PMID: 34603836, DOI: 10.1007/s40670-021-01355-2.Peer-Reviewed Original Research
2020
Identifying Associations Between Influenza Vaccination Status and Access, Beliefs, and Sociodemographic Factors Among the Uninsured Population in Suffolk County, NY.
Chen G, Kazmi M, Chen D, Phillips J. Identifying Associations Between Influenza Vaccination Status and Access, Beliefs, and Sociodemographic Factors Among the Uninsured Population in Suffolk County, NY. J Community Health 2020, 45: 1236-1241. PMID: 32607750, DOI: 10.1007/s10900-020-00873-1.Peer-Reviewed Original ResearchLipidomic profiling identifies signatures of metabolic risk.
Yin X, Willinger CM, Keefe J, Liu J, Fernández-Ortiz A, Ibáñez B, Peñalvo J, Adourian A, Chen G, Corella D, Pamplona R, Portero-Otin M, Jove M, Courchesne P, van Duijn CM, Fuster V, Ordovás JM, Demirkan A, Larson MG, Levy D. Lipidomic profiling identifies signatures of metabolic risk. EBioMedicine 2020, 51: 102520. PMID: 31877415, DOI: 10.1016/j.ebiom.2019.10.046.Peer-Reviewed Original Research
2018
Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.
Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun 2018, 9: 3268. PMID: 30111768, DOI: 10.1038/s41467-018-05512-x.Peer-Reviewed Original ResearchProtein Biomarkers of Cardiovascular Disease and Mortality in the Community.
Ho JE, Lyass A, Courchesne P, Chen G, Liu C, Yin X, Hwang SJ, Massaro JM, Larson MG, Levy D. Protein Biomarkers of Cardiovascular Disease and Mortality in the Community. J Am Heart Assoc 2018, 7 PMID: 30006491, DOI: 10.1161/JAHA.117.008108.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- August 14, 2024
Welcome New Staff, Faculty, Fellows, Postgrads & Postdocs (August 2024)
- November 29, 2023
Introducing the 2024 Digestive Diseases Fellows!
- March 16, 2023
Discoveries & Impact (March 2023)