Publications

2025

• Unravelling the Immunological Enigma of Sickle Cell Disease: Current Understanding and Future Directions

  Jamwal S, Calhoun C, Mohanty S, Montgomery R, Krishnamurti L, Shaw A, Yildirim I. Unravelling the Immunological Enigma of Sickle Cell Disease: Current Understanding and Future Directions. Immunology 2025 PMID: 41387179, DOI: 10.1111/imm.70080.

  Peer-Reviewed Original Research

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• A Phase 1 Double-Blinded Trial to Evaluate Safety, Immunogenicity, and Dosing of Measles-Vectored Chikungunya Virus Vaccine (MV-CHIK) in Healthy Adults

  Winokur P, Hegmann T, Sahly H, Anderson E, Wagner N, Kaufman T, Keitel W, Atmar R, Yi J, Yildirim I, Kao C, Peters E, Stephens K, Rostad C, Dempsey W, Shahamatdar V, Beresney T, Tomashek K. A Phase 1 Double-Blinded Trial to Evaluate Safety, Immunogenicity, and Dosing of Measles-Vectored Chikungunya Virus Vaccine (MV-CHIK) in Healthy Adults. Journal Of Infectious Diseases 2025, jiaf571. PMID: 41313671, DOI: 10.1093/infdis/jiaf571.

  Peer-Reviewed Original Research

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• Validation of polyester nasal swabs for post-mortem SARS-CoV-2 diagnosis in Karachi, Pakistan: a prospective surveillance analysis

  Allana R, Aziz F, Belgaumi S, Kabir F, Yildirim I, Hotwani A, Malik F, Aguolu O, Muneer S, Ahsan N, Hasan Z, Omer S, Kazi A. Validation of polyester nasal swabs for post-mortem SARS-CoV-2 diagnosis in Karachi, Pakistan: a prospective surveillance analysis. Journal Of Global Health 2025, 15: 04288. PMID: 41264556, PMCID: PMC12634021, DOI: 10.7189/jogh.15.04288.

  Peer-Reviewed Original Research

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• Decontamination approaches and strategies for the prevention of sink drain-related healthcare-associated infections

  Tanner W, Mathew T, Roberts S, Dieter L, Healy H, Peaper D, Peccia J, Martinello R, Blake E, Trumpler J, Frye N, Nilsen E, Paek H, Boyce M, Mayeran C, Polcaro T, Hallet A, Greene-Upshaw L, Kashyap N, Martinello R, Roberts S, Murray T, Peaper D, Evans L, Hieftje K, Marks A, Weser V, Truesdell E, Crocker A, Tanner W, Peccia J, Dieter L, Healy H, Mathew T. Decontamination approaches and strategies for the prevention of sink drain-related healthcare-associated infections. Clinical Microbiology Reviews 2025, 38: e00061-24. PMID: 41269016, PMCID: PMC12697124, DOI: 10.1128/cmr.00061-24.

  Peer-Reviewed Original Research

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• Aerosol-based Exposure to Opportunistic Pathogens Originating from Hospital Sink Drains

  Dieter L, Bowie K, Luhung I, Healy H, Roberts S, Mathew T, Peaper D, Martinello R, Gerstein M, Peccia J. Aerosol-based Exposure to Opportunistic Pathogens Originating from Hospital Sink Drains. American Journal Of Infection Control 2025 PMID: 41198034, DOI: 10.1016/j.ajic.2025.10.030.

  Peer-Reviewed Original Research

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• Chronic pulmonary LPS exposure in cystic fibrosis drives maladaptive pro-inflammatory hematopoietic stem and progenitor cells

  Isler Mancuso R, Thompson E, Braga C, Oez H, Gudneppanavar R, Zhang P, Neves T, Krause W, Huang P, Murray T, Egan M, Bruscia E, Krause D. Chronic pulmonary LPS exposure in cystic fibrosis drives maladaptive pro-inflammatory hematopoietic stem and progenitor cells. Blood 2025, 146: 3175-3175. DOI: 10.1182/blood-2025-3175.

  Peer-Reviewed Original Research

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• Innate immune dysregulation in monocytes in sickle cell disease

  Hinderstein S, Vidal-Pedrola G, Mohanty S, Matos I, Alarcon F, Carbonella J, Calhoun C, Krishnamurti L, Shaw A, Yildirim I. Innate immune dysregulation in monocytes in sickle cell disease. Blood 2025, 146: 1155. DOI: 10.1182/blood-2025-1155.

  Peer-Reviewed Original Research

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• Influenza vaccine coverage, effectiveness, and disease burden among pediatric sickle cell patients in Connecticut from 2021-2024: A test-negative case-control study

  Nchekwube P, Kuzaro H, Cohen E, Calhoun C, Krishnamurti L, Pashankar F, Bakshi N, Yildirim I. Influenza vaccine coverage, effectiveness, and disease burden among pediatric sickle cell patients in Connecticut from 2021-2024: A test-negative case-control study. Blood 2025, 146: 4745-4745. DOI: 10.1182/blood-2025-4745.

  Peer-Reviewed Original Research

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• Characterizing social behavior relevant for infectious disease transmission in four low- and middle-income countries, 2021-2023

  Nelson K, Kiti M, Shiiba M, Sacoor C, Bardají A, Macicame I, Jamisse E, Tchavana C, José A, Cavele N, Maldonado H, Jarquin C, Ajsivinac H, Raghava V, Samuel P, Srinivasan R, Kazi M, Allana R, Kim S, Prasad P, Chen D, Liu C, Jenness S, Ahmed N, Aguolu O, Sundaram M, Yildirim I, Malik F, Melegaro A, Lopman B, Omer S. Characterizing social behavior relevant for infectious disease transmission in four low- and middle-income countries, 2021-2023. Nature Communications 2025, 16: 9586. PMID: 41168147, PMCID: PMC12575605, DOI: 10.1038/s41467-025-64850-9.

  Peer-Reviewed Original Research

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• Measles Resurgence and the Fragility of Herd Immunity: Implications for Pediatric Infectious Disease Practice

  Hijano D, Orenstein W, Oliveira C. Measles Resurgence and the Fragility of Herd Immunity: Implications for Pediatric Infectious Disease Practice. Journal Of The Pediatric Infectious Diseases Society 2025, 14: piaf094. PMID: 41105102, PMCID: PMC12581858, DOI: 10.1093/jpids/piaf094.

  Peer-Reviewed Original Research

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• Coronavirus Disease 2019 (COVID-19) Vaccination Coverage and Effectiveness Among Pediatric Transplant Recipients

  Cohen E, Hinderstein S, Carciofi E, Hopkins K, Kuzaro H, Yildirim I. Coronavirus Disease 2019 (COVID-19) Vaccination Coverage and Effectiveness Among Pediatric Transplant Recipients. Progress In Transplantation 2025, 35: 221-228. PMID: 41105146, DOI: 10.1177/15269248251383951.

  Peer-Reviewed Original Research

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• Game Playbooks 2.0: An Updated Strategy for Supporting Game-Based Behavior Change Interventions

  Truesdell E, Weser V, Murray T, Crocker A, Marks A, Martinello R, Hieftje K. Game Playbooks 2.0: An Updated Strategy for Supporting Game-Based Behavior Change Interventions. Proceedings Of The ACM On Human-Computer Interaction 2025, 9: 1021-1044. DOI: 10.1145/3748631.

  Peer-Reviewed Original Research

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• 194 Restoration of ezrin via calpain inhibition reinstates immune function in cystic fibrosis alveolar macrophages

  Gudneppanavar R, Essayas H, Braga C, Garrison A, Zhang P, Huang P, da Silva Neves T, Britto C, Egan M, Murray T, Bruscia E. 194 Restoration of ezrin via calpain inhibition reinstates immune function in cystic fibrosis alveolar macrophages. Journal Of Cystic Fibrosis 2025, 24: s111a-s111. DOI: 10.1016/s1569-1993(25)01813-2.

  Peer-Reviewed Original Research

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• 197 Reduced levels of active hepatocyte growth factor correlate with lung damage in a CF mouse model

  Krause W, da Silva Neves T, Braga C, Gudneppanavar R, Knight C, Britto C, Egan M, Murray T, Bruscia E. 197 Reduced levels of active hepatocyte growth factor correlate with lung damage in a CF mouse model. Journal Of Cystic Fibrosis 2025, 24: s113. DOI: 10.1016/s1569-1993(25)01816-8.

  Peer-Reviewed Original Research

• 365 Chronic lung inflammation in cystic fibrosis drives maladaptive trained Tmmunity in hematopoietic stem cells

  Braga C, Mancuso R, Thompson E, Oez H, Gudneppanavar R, Zhang P, da Silva Neves T, Huang P, Krause W, Murray T, Egan M, Krause D, Bruscia E. 365 Chronic lung inflammation in cystic fibrosis drives maladaptive trained Tmmunity in hematopoietic stem cells. Journal Of Cystic Fibrosis 2025, 24: s201. DOI: 10.1016/s1569-1993(25)01983-6.

  Peer-Reviewed Original Research

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• Bactericidal Efficacy of Ultraviolet-C Light on Virtual Reality Devices: In Vitro Assessment of Bacterial Killing

  Roberts S, Wright J, Mustafa M, Feinn R, Marks A, Hieftje K, Huang P, Martinello R, Murray T, Blake E, Trumpler J, Frye N, Nilsen E, Paek H, Boyce M, Mayeran C, Polcaro T, Hallet A, Greene-Upshaw L, Kashyap N, Peaper D, Evans L, Weser V, Truesdell E, Crocker A, Tanner W, Peccia J, Dieter L, Healy H, Mathew T. Bactericidal Efficacy of Ultraviolet-C Light on Virtual Reality Devices: In Vitro Assessment of Bacterial Killing. JMIR Formative Research 2025, 9: e70326. PMID: 41038799, PMCID: PMC12483473, DOI: 10.2196/70326.

  Peer-Reviewed Original Research

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• Clinical effectiveness of HPV vaccine by age at vaccination: a matched case-control study

  Oliveira C, Shapiro E, Sheth S, Ellingson M, Johnson N, Sullivan E, Querec T, Unger E, Niccolai L. Clinical effectiveness of HPV vaccine by age at vaccination: a matched case-control study. The Lancet Regional Health - Americas 2025, 51: 101225. PMID: 41019517, PMCID: PMC12465035, DOI: 10.1016/j.lana.2025.101225.

  Peer-Reviewed Original Research

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• Human monoclonal antibodies targeting A35 protect from death caused by mpox.

  Fantin RF, Yuan M, Park SC, Bozarth B, Cohn H, Ignacio M, Earl P, Civljak A, Laghlali G, Zhang D, Zhu X, Crandell J, Monteiro V, Clark JJ, Cotter C, Burkhardt M, Singh G, Warang P, García-Bernalt Diego J, Srivastava K, Lugo LA, Pischel L, PVI study group, Yildirim I, Omer SB, da Silva D, Krammer F, Bajic G, Simon V, Schotsaert M, Lucas C, Wilson IA, Moss B, Coelho CH. Human monoclonal antibodies targeting A35 protect from death caused by mpox. Cell 2025 PMID: 40865529, DOI: 10.1016/j.cell.2025.08.004.

  Peer-Reviewed Original Research

• Applying principles to practice: cleaning and disinfection of extended reality equipment used in healthcare settings

  Murray T, Shenoy E, Roberts S, Martinello R, Marks A, Hieftje K, Green C, Rothschild J, Shradar M, McKinney T, Hand L, Novosad S, Glowicz J. Applying principles to practice: cleaning and disinfection of extended reality equipment used in healthcare settings. Infection Control And Hospital Epidemiology 2025, 46: 855-857. PMID: 40826908, PMCID: PMC12483620, DOI: 10.1017/ice.2025.10249.

  Peer-Reviewed Original Research

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• Evaluating the burden of respiratory tract infections among mortality cases in Karachi, Pakistan: a post-pandemic surveillance analysis

  Kabir F, Allana R, Yildirim I, Hotwani A, Belgaumi S, Aziz F, Malik F, Jamal S, Aguolu O, Ahsan N, Hasan Z, Ariff S, Omer S, Kazi A. Evaluating the burden of respiratory tract infections among mortality cases in Karachi, Pakistan: a post-pandemic surveillance analysis. Journal Of Global Health 2025, 15: 04198. PMID: 40755024, PMCID: PMC12319414, DOI: 10.7189/jogh.15.04198.

  Peer-Reviewed Original Research

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• Storage stability of non-encapsulated pneumococci in saliva is dependent on null-capsule clade, with strains carrying aliC and aliD showing a competitive disadvantage during culture enrichment

  Laxton C, Allicock O, Peno C, Lin T, Koelewijn A, Toekiran F, Aguilar L, York A, Wyllie A. Storage stability of non-encapsulated pneumococci in saliva is dependent on null-capsule clade, with strains carrying aliC and aliD showing a competitive disadvantage during culture enrichment. Microbiology 2025, 171: 001585. PMID: 40748653, PMCID: PMC12316466, DOI: 10.1099/mic.0.001585.

  Peer-Reviewed Original Research

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• Multicenter Prospective Cohort Study of CMV T Cell Immunity and First Post-Transplant CMV DNAemia in Pediatric Solid Organ Transplant Recipients

  Dulek D, Sun Y, Pellett-Madan R, Ferrolino J, Schuster J, Yildirim I, Sharma T, Foca M, Herold B, Muller W, Tang L, Michaels M, Kleiboeker S, Green M, Danziger-Isakov L. Multicenter Prospective Cohort Study of CMV T Cell Immunity and First Post-Transplant CMV DNAemia in Pediatric Solid Organ Transplant Recipients. American Journal Of Transplantation 2025, 25: s166-s167. DOI: 10.1016/j.ajt.2025.07.365.

  Peer-Reviewed Original Research

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• Influenza Vaccine Effectiveness and Disease Burden in Children and Adolescents with Solid Organ Transplant: 2018-2024

  Barisano D, Cohen E, Laviero H, Yildirim I, Serluco A, Nance G, Nchekwube P, Gonzalez M, Chen J. Influenza Vaccine Effectiveness and Disease Burden in Children and Adolescents with Solid Organ Transplant: 2018-2024. American Journal Of Transplantation 2025, 25: s165. DOI: 10.1016/j.ajt.2025.07.361.

  Peer-Reviewed Original Research

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• Determining the cause of death through mortality surveillance using verbal autopsy in Karachi, Pakistan

  Allana R, Yildirim I, Ariff S, Belgaumi S, Ahsan N, Aguolu O, Umair S, Ali S, Maqsood T, Iqbal M, Malik F, Omer S, Kazi A. Determining the cause of death through mortality surveillance using verbal autopsy in Karachi, Pakistan. Journal Of Global Health 2025, 15: 04199. PMID: 40689473, PMCID: PMC12278687, DOI: 10.7189/jogh.15.04199.

  Peer-Reviewed Original Research

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• Community health workers identify children requiring health center admission in Northern Uganda: prehospital risk prediction using vital signs and advanced point-of-care tests

  Ebbs D, Denish O, Bongomin F, Chandna A, Haseefa F, Canarie M, Cappello M. Community health workers identify children requiring health center admission in Northern Uganda: prehospital risk prediction using vital signs and advanced point-of-care tests. Global Health Action 2025, 18: 2519704. PMID: 40569209, PMCID: PMC12203686, DOI: 10.1080/16549716.2025.2519704.

  Peer-Reviewed Original Research

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