A Staring Spell
Hal Blumenfeld, MD, PhD, Yale School of Medicine professor of neurology and director of the Yale Clinical Neuroscience Imaging Center, describes the journey of validating an animal for measuring behavioral response during absence epilepsy, understanding the neuronal basis for the condition, and the path toward identifying targeted therapies.Source: Yale Scientific
Study Identifies Neuronal Basis of Impaired Consciousness in Absence Epilepsy
Using a genetic model known as Genetic Absence Epilepsy Rats of Strasbourg (GAERS), Yale researchers have identified the neuronal basis for absence epilepsy. Their findings were published Jan. 10 in Nature Communications. During absence epilepsy episodes, children experience brief staring spells, during which they temporarily lose consciousness. Absence seizures can be captured by abnormal rhythms on EEG recordings, but their neuronal cause has never before been identified.
Research Applies Machine Learning/AI to Predict Consciousness for Driving in People with Epilepsy
A new study published in September 2022 in Annals of Clinical and Translational Neurology may guide doctors in how to proceed when they observe SWDs on EEG, but are unclear of the patient’s neurological capacity for driving. Led by Principal Investigator Hal Blumenfeld, MD, PhD, researchers have harnessed the power of machine learning/artificial intelligence (AI) to address the shortcomings of traditional testing.
Long COVID and Cognitive Dysfunction: Searching for Answers
Gilbert H. Glaser professor of Neurology and chief of the Division of Neurological Infections and Global Neurology Serena Spudich, MD shares her knowledge of cognitive dysfunction in long-COVID patients, research conducted in her COVID Mind Study and Yale program, and what treatment options are currently available.Source: TheBodyPro
Philanthropist Nancy Davis Opens Up About Life with Multiple Sclerosis and Her Mission to Help Others
Philanthropist Nancy Davis tells her story of living with multiple sclerosis, from her diagnosis after a ski accident to how she eventually found the treatment plan that was right for her. Yale Neurology Chair David Hafler, MD also speaks about how far research into the autoimmune disease has come and what the most effective treatment strategies are.Source: People
Yale experts make strides in Multiple Sclerosis research
Yale School of Medicine researchers have furthered our understanding of the immune mechanisms of multiple sclerosis, discovered that B-cell depleting drugs reduce symptoms of inflammation in MS patients, and have made significant strides in earlier diagnoses.Source: Yale Daily News
Naila Makhani, MD, MPH, named Harry Weaver Neuroscience Scholar by the National Multiple Sclerosis Society
Naila Makhani, MD, MPH, has been named a Harry Weaver Neuroscience Scholar by the National Multiple Sclerosis (MS) Society, starting in July of 2022. The five-year early-career award is highly competitive and prestigious –a limited number of awards are given out by the National Multiple Sclerosis Society to highly qualified newly-independent researchers.
Less Wattage, More Brain Power
Dennis Spencer, MD, the Harvey and Kate Cushing Professor Emeritus of Neurosurgery, and Hitten Zaveri, PhD, assistant professor of neurology are collaborating with researchers at the Yale School of Engineering and Applied Science to expand the treatment capabilities of Brain-Computer Interfaces for patients who suffer from conditions like epilepsy and paralysis.Source: Yale News/Yale Engineering Magazine)
Yale School of Medicine starting trials on new epilepsy treatment that uses smart technology
About one-third of people diagnosed with epilepsy are not able to get relief from treatments currently available. Now, researchers at Yale University School of Medicine and two other locations are beginning trials on a new and innovative treatment that uses smart technology.Source: WTNH News 8
$3.59M NIMH Grant Awarded to Serena Spudich, MD
A new, five-year, $3.59M grant from the National Institute of Mental Health (NIMH) was awarded to Principal Investigator Serena Spudich, MD, Gilbert Glaser Professor of Neurology at Yale, along with co-PI, Joshua Cyktor, PhD, of the University of Pittsburgh.
AAN 2021 Virtual Annual Meeting: Highlights
Each year, the American Academy of Neurology (AAN) hosts a meeting wherein neurologists nationwide convene to present on their latest research findings and to learn from their peers. The following members of Yale Neurology presented abstracts at the 2021 virtual annual meeting:
CELLO Study to Explore Early Treatment of Multiple Sclerosis
Yale University announced today the initiation of a multicenter study aimed at treating early stage multiple sclerosis (MS). Supported by and in collaboration with Genentech, a member of the Roche Group, the study, known as “CELLO,” will investigate whether short-term treatment with ocrelizumab in patients with MRI lesions consistent with early MS without clinical disease—known as radiologic isolated syndrome—prevents the onset of symptoms.