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Lung Ultrasound (LUS) Part 2

July 29, 2021
  • 00:06OK, so now that we have pneumothorax
  • 00:09and pleural effusion under our belts,
  • 00:11we will move on to lung pocus for
  • 00:14pediatric pneumonia and pearls and
  • 00:15pitfalls necessary to be able to
  • 00:18differentiate this entity from other
  • 00:20causes of lower airway inflammation.
  • 00:24So one of the challenges for us
  • 00:27clinicians in diagnosing pediatric
  • 00:28pneumonia is that the physical
  • 00:30exam has an inherent limitations.
  • 00:33In order for us to accurately
  • 00:35differentiate other causes of
  • 00:37lower airway disease in children.
  • 00:39And this is nicely described in
  • 00:42the JAMA 2017 Rational clinical
  • 00:43Examination Systematic Review series
  • 00:45on the topic of pediatric pneumonia.
  • 00:48And so using an infiltrate on chest X ray
  • 00:52as a reference standard for this diagnosis.
  • 00:55There was no single finding that
  • 00:58could reliably differentiate
  • 00:59pneumonia from other causes of
  • 01:01childhood respiratory illness.
  • 01:03While two of the least important
  • 01:05predictors included tachypnoea and
  • 01:07lung findings on the physical exam.
  • 01:12So this JAMA report is really eye
  • 01:15opening because it really puts into
  • 01:18question how much time we should
  • 01:20even be spending on a lung exam
  • 01:23using a stethoscope as opposed to
  • 01:25harnessing our skills to perform
  • 01:27high quality lung pocus exams with
  • 01:30a general awareness of potential
  • 01:32limitations of this modality as well.
  • 01:38So if you look at what's been published
  • 01:41in terms of lung ultrasound for the
  • 01:44diagnosis of childhood pneumonia,
  • 01:47the findings to date are very encouraging.
  • 01:50We have meta analysis data published
  • 01:52from 2015 and the Journal of Pediatrics
  • 01:56in which they evaluated 8 studies,
  • 01:59of which five used highly skilled
  • 02:02operators with experience in
  • 02:04long ultrasound in 765 children.
  • 02:06Lung point of care.
  • 02:08Ultrasound had a sensitivity
  • 02:09of 96% and specificity of 93%
  • 02:12to detect pediatric pneumonia.
  • 02:14All studies incorporated
  • 02:15the use of the linear probe.
  • 02:18However, the reference standard
  • 02:19did have some heterogeneity as
  • 02:22some studies used at chest X ray
  • 02:24alone as the criterion standard,
  • 02:26while others incorporated both clinical
  • 02:29findings with chest X ray results.
  • 02:34So with the linear probe you will
  • 02:36perform a rapid assessment to
  • 02:38interrogate all six lung zones.
  • 02:41He would start with the probe
  • 02:43and the Midclavicular line and
  • 02:45the anterior lung field with the
  • 02:48indicator towards the patient's head,
  • 02:50and slide the transducer
  • 02:52down towards the diaphragm,
  • 02:53and you're going to repeat these
  • 02:56motions in the midaxillary
  • 02:58line as shown and again to the
  • 03:01posterior lung fields like so.
  • 03:03And you would repeat on
  • 03:05the contralateral side.
  • 03:08Now for the most part,
  • 03:10if everything looks normal on the
  • 03:12monitor and you're seeing good at a
  • 03:14lines with this agile orientation,
  • 03:15you can move on to the next zone.
  • 03:18That said, when something jumps
  • 03:19out at me as being abnormal,
  • 03:21such as a break in the pleural line,
  • 03:23or perhaps there's the
  • 03:24start of some beelines,
  • 03:26I will at this point rotate the
  • 03:28probe on that same spot to change
  • 03:30the angle of insulation and try
  • 03:32to get a good overall picture as
  • 03:34to what's going on in this area
  • 03:36of the lung that has an abnormal.
  • 03:38Finding so let's start by taking a look
  • 03:42at what normal lung ultrasound looks like.
  • 03:45Air, as you know,
  • 03:47is a poor transmitter of ultrasound,
  • 03:49so we're not really seeing
  • 03:50lung tissue on the screen,
  • 03:52but rather the artifacts that are
  • 03:54created by the interface of the pleura
  • 03:57with airfield alviola right behind it.
  • 03:59So in this example you have a ping
  • 04:01pong effect from the ultrasound
  • 04:03beam as it directs that first
  • 04:06bright line in the center of the
  • 04:08screen which is the pleura.
  • 04:10And this ping pong effect will cause
  • 04:13reverberation artifacts known as a
  • 04:15lines that are essentially equidistant
  • 04:18from the distance between the probe on
  • 04:20the patient's chest to the plural line.
  • 04:23And the reason for these equidistant
  • 04:25lines is really the well known formula
  • 04:29distance equals velocity times times.
  • 04:31So the ultrasound beam velocity
  • 04:33is a constant,
  • 04:34so it changes is how long it
  • 04:37takes for the ultrasound beam
  • 04:39to travel to get reflected.
  • 04:41Of the pleura.
  • 04:42Depending on the size of the chest
  • 04:45wall and the age of the patient
  • 04:47and so these a lines that are
  • 04:49created behind the pleura are the
  • 04:52same distance from one another.
  • 04:53So the important point here is that a
  • 04:56lines are good and normal and reflect well.
  • 04:59Aerated healthy lung tissue and the
  • 05:01absence of a lines tends to signal
  • 05:03some pathology within the lungs.
  • 05:07So in contrast, B lines are bad and
  • 05:10they are actually created by a different
  • 05:13type of reverberation artifact.
  • 05:15But the lines are a reverberation
  • 05:17artifact nonetheless.
  • 05:18So what tends to happen here
  • 05:20is that when you have wet lung
  • 05:23or fluid filled alveolar sacs,
  • 05:26the ultrasound beam gets trapped within
  • 05:28these fluid filled bubbles and the
  • 05:31ping pong effect rather than occurring
  • 05:33between the probe and the pleura,
  • 05:35actually happens within.
  • 05:37The inflamed and fluid filled
  • 05:39alveoli instead,
  • 05:39and so the images that is created is a
  • 05:43series of tightly packed horizontal lines,
  • 05:46one on top of the other that dive all the
  • 05:49way down to the bottom of the screen,
  • 05:53and as beelines become more diffuse
  • 05:55and more prominent on your monitor,
  • 05:58this is going to be linked with a
  • 06:00more severe process of interstitial
  • 06:03alveolar disease.
  • 06:06OK, so here we have some examples
  • 06:09of abnormal findings by lung
  • 06:11ultrasound in the clip on the left
  • 06:13using high frequency linear probe,
  • 06:15you're able to see a series of the
  • 06:18lines that are all diving down to
  • 06:21the bottom of the screen which are
  • 06:23starting from one area of confluence
  • 06:26between two rib spaces on the
  • 06:28pleura and on the right sided video
  • 06:31clip you can see beelines as would
  • 06:33be created using a phased array.
  • 06:36Transducer again,
  • 06:37these tightly packed horizontal
  • 06:38reverberation artifacts can be
  • 06:40seen to dive all the way down
  • 06:42to the bottom of the screen and
  • 06:44there are no clear lines visible,
  • 06:45so this pattern would always be abnormal
  • 06:48when performing a lung ultrasound.
  • 06:52So when we think about diagnosing lung
  • 06:54alter sound by pony culture sound,
  • 06:57there is a spectrum of findings.
  • 06:59Some of the earlier findings would
  • 07:01be the presence of Beelines alone,
  • 07:03and these can be.
  • 07:05Differentiated into isolated versus conflict,
  • 07:07with confluent being a more concerning
  • 07:10finding and you want to just train
  • 07:13yourself to be a good detective
  • 07:16of pleural changes so you will
  • 07:19become accustomed to disruptions of
  • 07:21the pleural line being a possible
  • 07:24early end concerning finding to
  • 07:26suggest underlying pneumonia and
  • 07:28finally with these plural line
  • 07:31disruptions you can have small sub
  • 07:34centimeter subpleural lesions.
  • 07:35Or collections which are unfortunately
  • 07:38nonspecific and could reflect
  • 07:40either atelectasis or the start
  • 07:42of a infiltrative process.
  • 07:46So here we have a 2 year old boy with
  • 07:49bronchiolitis and reactive airway disease.
  • 07:52You can see over the center of
  • 07:55the screen there is a small divot
  • 07:57and a dip in that pleural line,
  • 08:00so although this would potentially
  • 08:02some lower airway process we should not
  • 08:05be using this finding alone to make
  • 08:07a diagnosis of pediatric pneumonia
  • 08:09by long ultrasound as this is a
  • 08:11very mild and non specific finding.
  • 08:17These following clips show and additional.
  • 08:19I would say progression of
  • 08:21the spectrum of findings.
  • 08:23So on the 1st clip on the left hand side
  • 08:27there is a linear probe and you can see
  • 08:30again disruption of the pleural line.
  • 08:33We would call this an isolated beeline focus
  • 08:37emanating from the same spot in the pleura.
  • 08:40These are tough because they could reflect
  • 08:43early pneumonia versus atelectasis.
  • 08:46On the clip on the right hand side you
  • 08:49can see a greater confluence of the lines,
  • 08:54which again are arising from
  • 08:56a single subpleural focus.
  • 08:58What I would typically do here is
  • 09:02rotate the probe 360 degrees to see
  • 09:05if there are additional findings,
  • 09:08such as air bronchograms or other
  • 09:10signs of nearby lung consolidation.
  • 09:16So here's a good example
  • 09:18of what I'm talking about.
  • 09:19This is a 5 year old with right
  • 09:22upper lobe pneumonia as diagnosed
  • 09:24by lung point of care ultrasound.
  • 09:27With an essentially
  • 09:29unremarkable X-ray at the time,
  • 09:31you can see where the arrow is
  • 09:34placed on the ultrasound image.
  • 09:36There is a confluence of the
  • 09:39lines emanating from the pleura.
  • 09:41As this image is obtained over the
  • 09:44posterior upper lung zone and here
  • 09:46there is a lesion which is bigger
  • 09:48than one centimeter that represents
  • 09:51potential aspiration pneumonia.
  • 09:53That clinically was patient
  • 09:55had some risk factors for so.
  • 09:58Although the X ray was unremarkable,
  • 10:00we did initiate a course of augmentin
  • 10:03and I happened to call the mom the next
  • 10:05day or so who reported improved fever
  • 10:08and also improved worker breathing.
  • 10:10So we were pretty happy with this
  • 10:12outcome that we were able to use
  • 10:14ultrasound to augment our physical exam
  • 10:16to provide the best possible treatment.
  • 10:19Recommendations for this family.
  • 10:23And so here in this patient it was
  • 10:25a five week old with the left upper
  • 10:28lobe infiltrate as diagnosed by X-ray.
  • 10:31And you can see on ultrasound
  • 10:33with the linear probe.
  • 10:34There are confluent be lines
  • 10:36which are spanning across multiple
  • 10:38rib spaces so that it's not just
  • 10:40emanating from a single focus or
  • 10:42a single area of the pleura.
  • 10:44And so this pattern where there is
  • 10:47a larger area of lung involvement
  • 10:49is of course a more concerning.
  • 10:51Finding requires careful interpretation.
  • 10:52And judicious next steps,
  • 10:54especially in a patient that's so young.
  • 10:57So if these findings are diffused
  • 10:59and seen to all long,
  • 11:01then I would interpret as bronchiolitis or
  • 11:05diffuse multifocal pneumonia as opposed to.
  • 11:07In this case it was a symmetric.
  • 11:10So this would suggest some more focal
  • 11:13process of lung tissue consolidation.
  • 11:16Here is another example using
  • 11:18a curvilinear probe.
  • 11:19As this patient is having an
  • 11:21assessment of the loan basis for
  • 11:24likely for a pleural effusion X-ray
  • 11:27consistent with the right middle lobe
  • 11:29infiltrate and you can once again see.
  • 11:34Confluent felines spanning multiple rib
  • 11:35spaces in this patient with pneumonia.
  • 11:38So the tradeoff here is penetration
  • 11:40for resolution.
  • 11:41This is a cover linear probe eval
  • 11:43probably for a pleural effusion,
  • 11:46which is not present.
  • 11:47So although we don't see the pleura
  • 11:50as large and as crisply as we've
  • 11:52been viewing with the linear probe,
  • 11:55you can still get a sense that
  • 11:57these be lines.
  • 11:59Dip all the way down to the
  • 12:01bottom of the screen, even when a.
  • 12:04Lower frequency transducer is
  • 12:06used to scan the lungs.
  • 12:11And finally, here's a 6 year
  • 12:13old drowning victim who arrived
  • 12:15vomiting a pool water but was not
  • 12:18intimidated at the time of this scan.
  • 12:20You can see that there's diffuse
  • 12:22beelines seen throughout all longfields,
  • 12:25and so these are some extra findings
  • 12:27on linear probe interrogation of
  • 12:30the right lung in the left lung and
  • 12:33the bee lines can be seen using the
  • 12:36cardiac or phased array probe as well,
  • 12:39although the beeline artifacts in
  • 12:40this case actually stem from the
  • 12:43diaphragm with otherwise good mirror
  • 12:45imaging and no thoracic spine sign,
  • 12:47so this would exclude pleural
  • 12:49effusion or any.
  • 12:51Lower lobe pneumonia in this area.
  • 12:56And so here in the next set of images
  • 12:59that we're going to look at will be
  • 13:03more advanced findings for pneumonia,
  • 13:05and so these include air bronchograms,
  • 13:08which can either be static or dynamic.
  • 13:13The presence of a shred sign, pleural,
  • 13:16shred sign and hepatization of lung tissue.
  • 13:22So in this three year old patient with
  • 13:25left upper lobe pneumonia by X ray,
  • 13:27which can be seen at pretty clearly
  • 13:29on at the lateral projection.
  • 13:32Lung ultrasound shows static air
  • 13:34bronchograms which are created by
  • 13:36these white punctate spots where
  • 13:39you would otherwise expect to have
  • 13:41a lines if there was normal aerated
  • 13:44lung tissue and I really love this
  • 13:46clip because you can see towards
  • 13:48the left of the screen above the
  • 13:51rib there's an area of multiple
  • 13:54beelines with some confluence,
  • 13:56which if I had seen that alone I
  • 13:58would have been suspicious about
  • 14:01surrounding atelectasis.
  • 14:02Or lung tissue consolidation.
  • 14:06A static or bronchograms can be
  • 14:08tricky because they could be seen
  • 14:10in both pneumonia and atelectasis,
  • 14:12so you really have to correlate
  • 14:15this finding to the clinical exam,
  • 14:17and these are probably instances where
  • 14:19you want to get a chest film as well,
  • 14:23and together with the lung ultrasound you
  • 14:25can make a more accurate interpretation
  • 14:27of the ultrasound findings. In contrast,
  • 14:30dynamic air bronchograms as seen here,
  • 14:32which are reflected by fluid mucus,
  • 14:34phlegm buildup within the
  • 14:36bronchi and bronchioles.
  • 14:37Are the most specific finding for
  • 14:39pediatric pneumonia by lung ultrasound.
  • 14:42However, the incidence of finding
  • 14:44dinamico bronchograms is relatively low,
  • 14:46but you can see here on this clip
  • 14:48motion of the fluid filled bronchi
  • 14:51and you can almost make out the airway
  • 14:54tree and so this is a great example
  • 14:57of what you would be looking for in
  • 15:00terms of dynamic air bronchograms
  • 15:02which have been found to be the most
  • 15:06specific finding for pneumonia.
  • 15:08Using lung ultrasound.
  • 15:10Here we have a 6 year old with
  • 15:14sickle cell disease and acute chest
  • 15:17syndrome as seen by X ray.
  • 15:20In order to have bibasilar airspace
  • 15:23opacities and of course the differential
  • 15:26would be pneumonia versus atelectasis
  • 15:29versus vaso occlusive changes by ultrasound.
  • 15:33You can see a pleural disruption
  • 15:36and shred sign in both the right
  • 15:39and the left posterior lung fields.
  • 15:42The pathology on the right is
  • 15:44somewhat smaller.
  • 15:45Here you can see towards the right
  • 15:48of the screen the diaphragm,
  • 15:50the double line of the diaphragm
  • 15:53with the liver right below it and you
  • 15:57can see disruption and shred of the
  • 16:00pleura with B lines that are diving down.
  • 16:04From the pleural interface and so
  • 16:06the lesion on the left is actually
  • 16:09much much bigger.
  • 16:11There you don't see that clear,
  • 16:13crisp pleura that echogenic
  • 16:15line between the rib spaces.
  • 16:17Because there is tissue consolidation
  • 16:19there instead.
  • 16:20So the shred sign is actually far
  • 16:23lower on the screen about where
  • 16:26the four centimeter marker is,
  • 16:28and this is correlated with the X
  • 16:31ray that appeared to be far worse.
  • 16:34On the left compared to the right.
  • 16:39And here we have a 12 year old with asthma
  • 16:42who also presented with respiratory distress,
  • 16:46found to have pneumonia by X ray and
  • 16:48on lung ultrasound. You can see a
  • 16:51clear hepatization of the lung tissue.
  • 16:53So the probe in this case is a phased
  • 16:56array probe which is placed in the
  • 16:59left anterior zone above the heart.
  • 17:02As you can see on the ultrasound image
  • 17:05the heart is beating on the right side.
  • 17:08And what appears to be liver above it.
  • 17:12But in fact this is diseased lung
  • 17:15tissue which would be reflective
  • 17:17of more advanced pneumonia.
  • 17:20So lines are missing.
  • 17:21And because the disease process is
  • 17:24parenchymal and not solely at the level
  • 17:27of the alveolae or the interstitium,
  • 17:30you do not see any B lines on this image
  • 17:34but just advanced lung tissue consolidation.
  • 17:38Otherwise known as Hepatization because
  • 17:41of the similarities in appearance
  • 17:43when comparing this to the normal
  • 17:46appearance of liver by ultrasound.
  • 17:51So we don't know what the future
  • 17:54impact of lung focus will be.
  • 17:57I believe there are three potential outcomes,
  • 18:00one with integration of the clinical exam.
  • 18:03We hope that pediatric pneumonia
  • 18:06diagnosis can become more reliable.
  • 18:08Ideally, we can make a earlier
  • 18:10diagnosis and reduce the overall
  • 18:13burden of chest radiography.
  • 18:15Another potential impact is over
  • 18:18prescription of antibiotics as.
  • 18:20There's no way to fees abli or reliably
  • 18:23differentiate a viral pneumonia from
  • 18:26a bacterial pneumonia by ultrasound.
  • 18:29And finally,
  • 18:30there's a possibility that we may
  • 18:33actually prescribe less antibiotics.
  • 18:35Given again,
  • 18:36the limitations in the physical
  • 18:38exam and lack of reliability
  • 18:41that X ray has to differentiate
  • 18:44a viral from bacterial process.
  • 18:49So this would be an example of the
  • 18:52first outcome, greater position
  • 18:53and more accurate diagnosis.
  • 18:55So 6 year old male with Hemoglobin SC
  • 18:58presented with fever for two days and
  • 19:01shortness of breath on exam had some
  • 19:03slight elevation in the heart rate,
  • 19:06but otherwise normal oxygen saturation
  • 19:08exam with wheezing and diminished
  • 19:10breath sounds on the left side.
  • 19:12High typical work up was done for SC disease
  • 19:15with fever to include a chest X ray and.
  • 19:19Lab work which revealed no
  • 19:21Leukocytosis on the X ray.
  • 19:24There was no acute cardio
  • 19:26thoracic abnormality as per
  • 19:28the radiologist interpretation.
  • 19:32However, by lung focus there is clear
  • 19:36shred sign in the left posterior
  • 19:39lung field with disruption of
  • 19:42the pleura and beelines emanating
  • 19:45from this jagged pleural edge.
  • 19:48This patient was subsequently admitted
  • 19:51with early recognition of acute
  • 19:53chest on given ceftriaxone and is it
  • 19:56through myosin as per our hematology
  • 19:59treatment recommendations and
  • 20:00incurred a three day hospitalization?
  • 20:03How luckily did not require any
  • 20:06PRBC transfusion and had multiple
  • 20:08negative blood cultures.
  • 20:09This case was several years before we
  • 20:12were routinely obtaining procalcitonin to
  • 20:15help rid stratified bacterial versus viral.
  • 20:18Pneumonia and a viral swab is not
  • 20:20performed as his patient was managed
  • 20:22in the hospital who did well and
  • 20:24completed his course for community
  • 20:26acquired pneumonia as an outpatient.
  • 20:31Here's another example of how we may
  • 20:34provide more efficient care with lung pocus.
  • 20:37So in this clinical case,
  • 20:39a 9 month old presented with
  • 20:42respiratory distress, and this was the
  • 20:443rd ER visit for the same illness.
  • 20:47Had a prior rhinovirus positive
  • 20:49tests in an X ray,
  • 20:51which during the first visit was
  • 20:53more in keeping with Perihilar and
  • 20:56peribronchial interstitial markings,
  • 20:58likely viral airway inflammation.
  • 21:00Most likely bronchiolitis, however,
  • 21:02ongoing fevers cough and some
  • 21:04posts of emesis and increasing
  • 21:05work of breathing and there was
  • 21:08strong family history of asthma.
  • 21:10This infant was takach Arctic with
  • 21:12takip NIA and exam was notable for
  • 21:14attractions and coarse breath sounds,
  • 21:16but no audible wheezes were present,
  • 21:18and the clinical team not only
  • 21:20did a long ultrasound,
  • 21:22but performed a cardiac ultrasound
  • 21:23as well to rule out any other
  • 21:26potential causes of compensated shock.
  • 21:31So interestingly, this infant had one
  • 21:34specific lung area of abnormality
  • 21:36in the left posterior lung field.
  • 21:39You can see here between those ribs.
  • 21:43There is an absence of that
  • 21:46pleural line and shred sign,
  • 21:48so we have a lesion that is certainly
  • 21:51abnormal and needs more thorough evaluation.
  • 21:57So a scan performed on the opposite side,
  • 22:01the right posterior lung field
  • 22:03is here as a comparison,
  • 22:05and you can see the intact pleura throughout.
  • 22:10Spaces and. There are essentially normal
  • 22:15a lines in the different lung zone.
  • 22:18As the probe slides from the top
  • 22:20of the patient down towards the
  • 22:23diaphragm in a sagittal plane.
  • 22:27And so we go back to the left side and
  • 22:31get another clear look here at this sub,
  • 22:35pleural abnormality,
  • 22:36where there's a break in the pleural line.
  • 22:40There's a shed sign and there are
  • 22:43static air bronchograms in this lesion,
  • 22:46demarcated by the arrow.
  • 22:48And So what you do here is you
  • 22:52turn the probe 90 degrees to try
  • 22:54and assess a complete picture.
  • 22:57Of this lesion, so when the probe
  • 23:00is rotated in a transverse plane,
  • 23:03you essentially see a confluence
  • 23:06of beelines dropping down from the
  • 23:09pleura as on the second ultrasound
  • 23:11clip here and again.
  • 23:13If you were to rotate it 90 degrees
  • 23:16with the indicator towards the
  • 23:19patient's head in a sagittal plane,
  • 23:22you would have made out this abnormal
  • 23:25consolidation which is highly suggestive.
  • 23:28Of a pneumonia.
  • 23:31So the clinical course was interesting
  • 23:34for this infant was admitted for
  • 23:36respiratory monitoring after
  • 23:38initiation of hydros amoxicillin for
  • 23:41this long ultrasound finding and X
  • 23:43ray at the time was not obtained and
  • 23:46had a pretty brief hospitalization.
  • 23:48Had no fever, antibiotics ended up
  • 23:50being a discontinued and was discharged
  • 23:53home after some period of monitoring,
  • 23:55which he seemed to do quite well.
  • 24:01Then three days later, he came back,
  • 24:04this now being the 4th ER visit with
  • 24:07persistent fever and respiratory distress,
  • 24:09at which point in X ray was repeated,
  • 24:13showing bilateral findings concerning
  • 24:15for pneumonia and amoxicillin was re
  • 24:18prescribed and able to be discharged home,
  • 24:20and he actually did quite well
  • 24:23without any further emergency
  • 24:24visits for labored breathing.
  • 24:29OK, so the next possible outcome is that
  • 24:32lung focus has the potential to lead to
  • 24:35the prescription of more antibiotics.
  • 24:38And I say this only because it is far
  • 24:40more sensitive to pick up abnormalities
  • 24:43when compared to X ray and viral
  • 24:46pneumonia findings and bacterial
  • 24:48pneumonia findings will have overlapped
  • 24:50and this has been well documented
  • 24:53to date with all the non specific
  • 24:56findings we see with COVID pneumonia.
  • 24:59Here in this case,
  • 25:00we present a 27 month old with respiratory
  • 25:03distress and fever in January 2020,
  • 25:06when COVID pneumonia may have been
  • 25:09circulating in the community.
  • 25:10We don't know for 100%
  • 25:13the symptoms consisted of.
  • 25:16Two to three weeks of cough worse
  • 25:18at night and one day a fever.
  • 25:21Ah was ill appearing on exam
  • 25:23with tachycardia,
  • 25:23low oxygen saturation and takip NIA.
  • 25:25Also was listless with flaring
  • 25:27and accessory muscle use and
  • 25:28diminished breath sounds throughout,
  • 25:30but perhaps were sitting in the right
  • 25:32upper lung field and the next rate
  • 25:34is shown showed no focal infiltrate.
  • 25:40Lang Focus performed in the right upper
  • 25:42lobe showed the following abnormality.
  • 25:45Disruption of the pleura,
  • 25:47shred sign belines and this lesion was
  • 25:51measured to be 1 1/2 centimeter and
  • 25:54concerning for the start of a pneumonia.
  • 26:00So this channel is emitted to the
  • 26:02ICU and IBM PASILAN was initiated
  • 26:05was treated with Bipap and required
  • 26:07continuous albuterol and steroids.
  • 26:10Interestingly, a procalcitonin test
  • 26:11came back normal chest X ray done.
  • 26:14The subsequent date revealed and was
  • 26:16read as a right upper lobe infiltrate
  • 26:19consolidation versus atelectasis,
  • 26:20and this correlated perfectly with the area
  • 26:23of the lung that was imaged the day before.
  • 26:27With that abnormal finding.
  • 26:29Had a three day hospitalization.
  • 26:32Was managed as a bronchiolitis,
  • 26:35a therapy with treatment of
  • 26:38reactive bronchospasm and all
  • 26:40viral tests were negative,
  • 26:42so this child improved fully without
  • 26:46completing a full course of antibiotics.
  • 26:50And finally,
  • 26:51lung ultrasound may have the potential
  • 26:53to decrease antibiotic overuse.
  • 26:55So here's a great example of a
  • 26:5810 month old male with a fever
  • 27:01and suspected pneumonia,
  • 27:02as per clinicians that are referring
  • 27:05hospital who had initiated amoxicillin
  • 27:07with an X ray obtained was read
  • 27:10as haziness in the left lung zone.
  • 27:13Suspicious for pneumonia.
  • 27:14However,
  • 27:15there are definitely some other
  • 27:17things going on clinically to include
  • 27:20a prior COVID positive PCR test
  • 27:2210 days before this presentation
  • 27:24and daily fever for four days.
  • 27:27Popular rash on the torso.
  • 27:29Some lesions to the lip,
  • 27:31gums,
  • 27:31and some swelling to the hands and
  • 27:34feet so multisystem picture and this
  • 27:37infant actually looked quite well
  • 27:39appearing and no respiratory distress.
  • 27:42Playful and unremarkable
  • 27:43physical examination,
  • 27:44and you can see the labs there had a
  • 27:47little thrombocytosis and a slight.
  • 27:50Elevation in the ESR and the CRP.
  • 27:56So in the PDE complete 6 zone,
  • 27:59longer sound was performed and well
  • 28:02tolerated and it revealed essentially the
  • 28:05following findings which run remarkable.
  • 28:08You can see a lines throughout all
  • 28:12the lung zones being interrogated,
  • 28:15and occasionally there's a little divot
  • 28:18at the level of the pleura, but no true.
  • 28:23B line with stacked,
  • 28:25horizontal reverberation dipping down all
  • 28:28the way down to the bottom of the screen.
  • 28:31No shred sign.
  • 28:33No static air bronchograms,
  • 28:34and certainly no signs of hepatization.
  • 28:37So based on these findings we
  • 28:39actually made the recommendation
  • 28:41to discontinue the amoxicillin.
  • 28:46And this little infant was actually
  • 28:49somewhat fascinating as it seemed to
  • 28:52have some sort of mild inflammatory
  • 28:55picture with a slightly elevated
  • 28:58BNP and a slightly elevated D dimer
  • 29:01was admitted for surveillance with
  • 29:03concern for MIC normal echocardiogram
  • 29:06during the admission, and there was
  • 29:09no progression or decompensation,
  • 29:11so the team was able to.
  • 29:14The first steroids and IVIG.
  • 29:17And had a great follow up visit
  • 29:1910 days later with normalization
  • 29:21of the inflammatory markers and
  • 29:23was clinically well appearing and
  • 29:26back to herself at this point.
  • 29:31So there's lots of further inquiry that
  • 29:34is necessary so that we can fine tune
  • 29:37how to integrate lung pocus as part of
  • 29:41our workups for pediatric pneumonia.
  • 29:43And it's possible that we will have to
  • 29:46incorporate long ultrasound findings
  • 29:48with not only physical exam but also
  • 29:51some laboratory values to make good
  • 29:54decisions about antibiotic stewardship.
  • 29:56And there's also some instances
  • 29:58where lung ultrasound.
  • 30:00Will have to be incorporated in
  • 30:02parallel with chest radiography
  • 30:04in certain instances to minimize
  • 30:06our risk for misdiagnosis.
  • 30:11And so here in this final case you can
  • 30:15see we have a 21 year old with fever,
  • 30:18wheezing and decreased
  • 30:19breath sounds on the right.
  • 30:21On this frontal projection of the X ray,
  • 30:24you can see that there is an
  • 30:26obvious abnormality that could
  • 30:28be interpreted as pneumonia.
  • 30:30If you put the lung probe as was done
  • 30:33in this case, right over this lesion,
  • 30:35you can see a mass like finding which
  • 30:38could be misconstrued as hepatization.
  • 30:40There is no lines.
  • 30:42There are no body lines.
  • 30:44There is no shred sign.
  • 30:46There is no static air bronchograms
  • 30:49and this tissue doesn't quite look
  • 30:51hypothesized like in the prior example.
  • 30:54So if you're up to obtain
  • 30:57a lateral chest X ray,
  • 30:59this diagnosis is more consistent
  • 31:01with the anterior mediastinal mass,
  • 31:03and this young man was subsequently
  • 31:06diagnosed with a lymphoma.
  • 31:07So the important point here
  • 31:10is that a chest wall mass.
  • 31:13We can mimic potentially the
  • 31:15appearance of hepatocytes lung tissue,
  • 31:17and this needs to be carefully
  • 31:19accounted for during the clinical
  • 31:21assessment of our patients.
  • 31:25A couple of other pitfalls and
  • 31:28potential false positives in the right
  • 31:31clinical scenario, sinus can appear.
  • 31:35Is a homogeneous you know appearing mass
  • 31:39typically is this is found anteriorly.
  • 31:44In front of the heart and can be seen.
  • 31:47In my experience both on the right side
  • 31:50and in the left side of the chest with
  • 31:53integration of the anterior lung fields.
  • 31:56So we must be able to recognize thymus
  • 31:58tissue as normal and actually one
  • 32:01of the keys for me is the plural.
  • 32:04So in this image of thymus you
  • 32:06can still make out the echogenic
  • 32:08bright pleura in between the rib
  • 32:11spaces and so that to me is a clear
  • 32:14indicator that this is not consistent.
  • 32:17With long hair participation or pneumonia.
  • 32:21Finally, in the left upper quadrant,
  • 32:24especially when assessing for.
  • 32:27A fusion with the curvilinear probe,
  • 32:30the stomach, when it is filled
  • 32:32with mixed content to include air,
  • 32:34can give off a bright echogenic appearance.
  • 32:37So you really want to be very
  • 32:39clear as to whether these findings
  • 32:42are above or below the diaphragm.
  • 32:44So in this particular image you're
  • 32:46not seeing the diaphragm clearly,
  • 32:48but you're seeing pleura at the
  • 32:51top of the screen,
  • 32:52next to the P with the lung sliding.
  • 32:55And so you see, pleura rib pleura.
  • 32:58Read you don't quite see the diaphragm,
  • 33:01but the spleen.
  • 33:02Is there,
  • 33:03UM,
  • 33:03right adjacent to the rib shadow
  • 33:05that is in the center of the screen
  • 33:08and the stomach with airfield and
  • 33:11mixed contents is giving off a
  • 33:13bright appearance behind this plane.
  • 33:16So location, location,
  • 33:17location and pattern recognition
  • 33:18and knowing your landmarks and what
  • 33:21you're looking for are going to
  • 33:23be very important to minimize your
  • 33:25false positive interpretations.
  • 33:29So this is such an exciting modality,
  • 33:32but we're clearly not doing this
  • 33:34protocolized on every patient,
  • 33:36and there are lots of reasons why this is so.
  • 33:40Number one from a practical standpoint,
  • 33:42it takes time, which it takes a longer
  • 33:45time for the setup and the process
  • 33:47of completing a high quality long
  • 33:50ultrasound in a infant and a toddler as
  • 33:53opposed to an X ray is just a quick.
  • 33:58Picture with a plate on the
  • 33:59back or on the side.
  • 34:01Patient cooperation does come into play here,
  • 34:04so you really have to.
  • 34:07Engage, you know the caregiver
  • 34:09to be a partner, and you know,
  • 34:12sometimes you know.
  • 34:13Patients just are not going to
  • 34:16tolerate either the gel or the probe,
  • 34:19or just the whole process in general and
  • 34:23we need adequate training and we need to
  • 34:26reach a level of competency across the
  • 34:30board that is not yet been well established.
  • 34:33And unfortunately,
  • 34:34when doing research around this topic.
  • 34:37There are serious challenges related
  • 34:40to assigning an incontrovertible
  • 34:42referenced or criterion standard,
  • 34:43but for resource limited settings and
  • 34:46for individuals who are comfortable
  • 34:48at performing lung ultrasound and
  • 34:51are able to interpret findings
  • 34:53in the clinical context,
  • 34:55this is an invaluable tool with tremendous
  • 34:58promise for the future care of our
  • 35:01pediatric patients with respiratory
  • 35:03distress or unexplained chest pain,
  • 35:06and there is certainly a lot of enthusiasm.
  • 35:10And momentum behind for lung pocus
  • 35:13to increase our position in emergency
  • 35:16medicine when we are challenged to make
  • 35:19clinical decisions with oftentimes
  • 35:22imperfect and limited information.
  • 35:28This concludes our introduction
  • 35:30to lung ultrasound Part 2.
  • 35:32We hope you find this
  • 35:35information useful and.
  • 35:36If there are any questions,
  • 35:38please don't hesitate to reach out,
  • 35:40otherwise we will see you
  • 35:41soon and this content will be
  • 35:43updated as deemed necessary.