Lung Ultrasound (LUS) Part 2
July 29, 2021ID6847
To CiteDCA Citation Guide
- 00:06OK, so now that we have pneumothorax
- 00:09and pleural effusion under our belts,
- 00:11we will move on to lung pocus for
- 00:14pediatric pneumonia and pearls and
- 00:15pitfalls necessary to be able to
- 00:18differentiate this entity from other
- 00:20causes of lower airway inflammation.
- 00:24So one of the challenges for us
- 00:27clinicians in diagnosing pediatric
- 00:28pneumonia is that the physical
- 00:30exam has an inherent limitations.
- 00:33In order for us to accurately
- 00:35differentiate other causes of
- 00:37lower airway disease in children.
- 00:39And this is nicely described in
- 00:42the JAMA 2017 Rational clinical
- 00:43Examination Systematic Review series
- 00:45on the topic of pediatric pneumonia.
- 00:48And so using an infiltrate on chest X ray
- 00:52as a reference standard for this diagnosis.
- 00:55There was no single finding that
- 00:58could reliably differentiate
- 00:59pneumonia from other causes of
- 01:01childhood respiratory illness.
- 01:03While two of the least important
- 01:05predictors included tachypnoea and
- 01:07lung findings on the physical exam.
- 01:12So this JAMA report is really eye
- 01:15opening because it really puts into
- 01:18question how much time we should
- 01:20even be spending on a lung exam
- 01:23using a stethoscope as opposed to
- 01:25harnessing our skills to perform
- 01:27high quality lung pocus exams with
- 01:30a general awareness of potential
- 01:32limitations of this modality as well.
- 01:38So if you look at what's been published
- 01:41in terms of lung ultrasound for the
- 01:44diagnosis of childhood pneumonia,
- 01:47the findings to date are very encouraging.
- 01:50We have meta analysis data published
- 01:52from 2015 and the Journal of Pediatrics
- 01:56in which they evaluated 8 studies,
- 01:59of which five used highly skilled
- 02:02operators with experience in
- 02:04long ultrasound in 765 children.
- 02:06Lung point of care.
- 02:08Ultrasound had a sensitivity
- 02:09of 96% and specificity of 93%
- 02:12to detect pediatric pneumonia.
- 02:14All studies incorporated
- 02:15the use of the linear probe.
- 02:18However, the reference standard
- 02:19did have some heterogeneity as
- 02:22some studies used at chest X ray
- 02:24alone as the criterion standard,
- 02:26while others incorporated both clinical
- 02:29findings with chest X ray results.
- 02:34So with the linear probe you will
- 02:36perform a rapid assessment to
- 02:38interrogate all six lung zones.
- 02:41He would start with the probe
- 02:43and the Midclavicular line and
- 02:45the anterior lung field with the
- 02:48indicator towards the patient's head,
- 02:50and slide the transducer
- 02:52down towards the diaphragm,
- 02:53and you're going to repeat these
- 02:56motions in the midaxillary
- 02:58line as shown and again to the
- 03:01posterior lung fields like so.
- 03:03And you would repeat on
- 03:05the contralateral side.
- 03:08Now for the most part,
- 03:10if everything looks normal on the
- 03:12monitor and you're seeing good at a
- 03:14lines with this agile orientation,
- 03:15you can move on to the next zone.
- 03:18That said, when something jumps
- 03:19out at me as being abnormal,
- 03:21such as a break in the pleural line,
- 03:23or perhaps there's the
- 03:24start of some beelines,
- 03:26I will at this point rotate the
- 03:28probe on that same spot to change
- 03:30the angle of insulation and try
- 03:32to get a good overall picture as
- 03:34to what's going on in this area
- 03:36of the lung that has an abnormal.
- 03:38Finding so let's start by taking a look
- 03:42at what normal lung ultrasound looks like.
- 03:45Air, as you know,
- 03:47is a poor transmitter of ultrasound,
- 03:49so we're not really seeing
- 03:50lung tissue on the screen,
- 03:52but rather the artifacts that are
- 03:54created by the interface of the pleura
- 03:57with airfield alviola right behind it.
- 03:59So in this example you have a ping
- 04:01pong effect from the ultrasound
- 04:03beam as it directs that first
- 04:06bright line in the center of the
- 04:08screen which is the pleura.
- 04:10And this ping pong effect will cause
- 04:13reverberation artifacts known as a
- 04:15lines that are essentially equidistant
- 04:18from the distance between the probe on
- 04:20the patient's chest to the plural line.
- 04:23And the reason for these equidistant
- 04:25lines is really the well known formula
- 04:29distance equals velocity times times.
- 04:31So the ultrasound beam velocity
- 04:33is a constant,
- 04:34so it changes is how long it
- 04:37takes for the ultrasound beam
- 04:39to travel to get reflected.
- 04:41Of the pleura.
- 04:42Depending on the size of the chest
- 04:45wall and the age of the patient
- 04:47and so these a lines that are
- 04:49created behind the pleura are the
- 04:52same distance from one another.
- 04:53So the important point here is that a
- 04:56lines are good and normal and reflect well.
- 04:59Aerated healthy lung tissue and the
- 05:01absence of a lines tends to signal
- 05:03some pathology within the lungs.
- 05:07So in contrast, B lines are bad and
- 05:10they are actually created by a different
- 05:13type of reverberation artifact.
- 05:15But the lines are a reverberation
- 05:17artifact nonetheless.
- 05:18So what tends to happen here
- 05:20is that when you have wet lung
- 05:23or fluid filled alveolar sacs,
- 05:26the ultrasound beam gets trapped within
- 05:28these fluid filled bubbles and the
- 05:31ping pong effect rather than occurring
- 05:33between the probe and the pleura,
- 05:35actually happens within.
- 05:37The inflamed and fluid filled
- 05:39alveoli instead,
- 05:39and so the images that is created is a
- 05:43series of tightly packed horizontal lines,
- 05:46one on top of the other that dive all the
- 05:49way down to the bottom of the screen,
- 05:53and as beelines become more diffuse
- 05:55and more prominent on your monitor,
- 05:58this is going to be linked with a
- 06:00more severe process of interstitial
- 06:03alveolar disease.
- 06:06OK, so here we have some examples
- 06:09of abnormal findings by lung
- 06:11ultrasound in the clip on the left
- 06:13using high frequency linear probe,
- 06:15you're able to see a series of the
- 06:18lines that are all diving down to
- 06:21the bottom of the screen which are
- 06:23starting from one area of confluence
- 06:26between two rib spaces on the
- 06:28pleura and on the right sided video
- 06:31clip you can see beelines as would
- 06:33be created using a phased array.
- 06:36Transducer again,
- 06:37these tightly packed horizontal
- 06:38reverberation artifacts can be
- 06:40seen to dive all the way down
- 06:42to the bottom of the screen and
- 06:44there are no clear lines visible,
- 06:45so this pattern would always be abnormal
- 06:48when performing a lung ultrasound.
- 06:52So when we think about diagnosing lung
- 06:54alter sound by pony culture sound,
- 06:57there is a spectrum of findings.
- 06:59Some of the earlier findings would
- 07:01be the presence of Beelines alone,
- 07:03and these can be.
- 07:05Differentiated into isolated versus conflict,
- 07:07with confluent being a more concerning
- 07:10finding and you want to just train
- 07:13yourself to be a good detective
- 07:16of pleural changes so you will
- 07:19become accustomed to disruptions of
- 07:21the pleural line being a possible
- 07:24early end concerning finding to
- 07:26suggest underlying pneumonia and
- 07:28finally with these plural line
- 07:31disruptions you can have small sub
- 07:34centimeter subpleural lesions.
- 07:35Or collections which are unfortunately
- 07:38nonspecific and could reflect
- 07:40either atelectasis or the start
- 07:42of a infiltrative process.
- 07:46So here we have a 2 year old boy with
- 07:49bronchiolitis and reactive airway disease.
- 07:52You can see over the center of
- 07:55the screen there is a small divot
- 07:57and a dip in that pleural line,
- 08:00so although this would potentially
- 08:02some lower airway process we should not
- 08:05be using this finding alone to make
- 08:07a diagnosis of pediatric pneumonia
- 08:09by long ultrasound as this is a
- 08:11very mild and non specific finding.
- 08:17These following clips show and additional.
- 08:19I would say progression of
- 08:21the spectrum of findings.
- 08:23So on the 1st clip on the left hand side
- 08:27there is a linear probe and you can see
- 08:30again disruption of the pleural line.
- 08:33We would call this an isolated beeline focus
- 08:37emanating from the same spot in the pleura.
- 08:40These are tough because they could reflect
- 08:43early pneumonia versus atelectasis.
- 08:46On the clip on the right hand side you
- 08:49can see a greater confluence of the lines,
- 08:54which again are arising from
- 08:56a single subpleural focus.
- 08:58What I would typically do here is
- 09:02rotate the probe 360 degrees to see
- 09:05if there are additional findings,
- 09:08such as air bronchograms or other
- 09:10signs of nearby lung consolidation.
- 09:16So here's a good example
- 09:18of what I'm talking about.
- 09:19This is a 5 year old with right
- 09:22upper lobe pneumonia as diagnosed
- 09:24by lung point of care ultrasound.
- 09:27With an essentially
- 09:29unremarkable X-ray at the time,
- 09:31you can see where the arrow is
- 09:34placed on the ultrasound image.
- 09:36There is a confluence of the
- 09:39lines emanating from the pleura.
- 09:41As this image is obtained over the
- 09:44posterior upper lung zone and here
- 09:46there is a lesion which is bigger
- 09:48than one centimeter that represents
- 09:51potential aspiration pneumonia.
- 09:53That clinically was patient
- 09:55had some risk factors for so.
- 09:58Although the X ray was unremarkable,
- 10:00we did initiate a course of augmentin
- 10:03and I happened to call the mom the next
- 10:05day or so who reported improved fever
- 10:08and also improved worker breathing.
- 10:10So we were pretty happy with this
- 10:12outcome that we were able to use
- 10:14ultrasound to augment our physical exam
- 10:16to provide the best possible treatment.
- 10:19Recommendations for this family.
- 10:23And so here in this patient it was
- 10:25a five week old with the left upper
- 10:28lobe infiltrate as diagnosed by X-ray.
- 10:31And you can see on ultrasound
- 10:33with the linear probe.
- 10:34There are confluent be lines
- 10:36which are spanning across multiple
- 10:38rib spaces so that it's not just
- 10:40emanating from a single focus or
- 10:42a single area of the pleura.
- 10:44And so this pattern where there is
- 10:47a larger area of lung involvement
- 10:49is of course a more concerning.
- 10:51Finding requires careful interpretation.
- 10:52And judicious next steps,
- 10:54especially in a patient that's so young.
- 10:57So if these findings are diffused
- 10:59and seen to all long,
- 11:01then I would interpret as bronchiolitis or
- 11:05diffuse multifocal pneumonia as opposed to.
- 11:07In this case it was a symmetric.
- 11:10So this would suggest some more focal
- 11:13process of lung tissue consolidation.
- 11:16Here is another example using
- 11:18a curvilinear probe.
- 11:19As this patient is having an
- 11:21assessment of the loan basis for
- 11:24likely for a pleural effusion X-ray
- 11:27consistent with the right middle lobe
- 11:29infiltrate and you can once again see.
- 11:34Confluent felines spanning multiple rib
- 11:35spaces in this patient with pneumonia.
- 11:38So the tradeoff here is penetration
- 11:40for resolution.
- 11:41This is a cover linear probe eval
- 11:43probably for a pleural effusion,
- 11:46which is not present.
- 11:47So although we don't see the pleura
- 11:50as large and as crisply as we've
- 11:52been viewing with the linear probe,
- 11:55you can still get a sense that
- 11:57these be lines.
- 11:59Dip all the way down to the
- 12:01bottom of the screen, even when a.
- 12:04Lower frequency transducer is
- 12:06used to scan the lungs.
- 12:11And finally, here's a 6 year
- 12:13old drowning victim who arrived
- 12:15vomiting a pool water but was not
- 12:18intimidated at the time of this scan.
- 12:20You can see that there's diffuse
- 12:22beelines seen throughout all longfields,
- 12:25and so these are some extra findings
- 12:27on linear probe interrogation of
- 12:30the right lung in the left lung and
- 12:33the bee lines can be seen using the
- 12:36cardiac or phased array probe as well,
- 12:39although the beeline artifacts in
- 12:40this case actually stem from the
- 12:43diaphragm with otherwise good mirror
- 12:45imaging and no thoracic spine sign,
- 12:47so this would exclude pleural
- 12:49effusion or any.
- 12:51Lower lobe pneumonia in this area.
- 12:56And so here in the next set of images
- 12:59that we're going to look at will be
- 13:03more advanced findings for pneumonia,
- 13:05and so these include air bronchograms,
- 13:08which can either be static or dynamic.
- 13:13The presence of a shred sign, pleural,
- 13:16shred sign and hepatization of lung tissue.
- 13:22So in this three year old patient with
- 13:25left upper lobe pneumonia by X ray,
- 13:27which can be seen at pretty clearly
- 13:29on at the lateral projection.
- 13:32Lung ultrasound shows static air
- 13:34bronchograms which are created by
- 13:36these white punctate spots where
- 13:39you would otherwise expect to have
- 13:41a lines if there was normal aerated
- 13:44lung tissue and I really love this
- 13:46clip because you can see towards
- 13:48the left of the screen above the
- 13:51rib there's an area of multiple
- 13:54beelines with some confluence,
- 13:56which if I had seen that alone I
- 13:58would have been suspicious about
- 14:01surrounding atelectasis.
- 14:02Or lung tissue consolidation.
- 14:06A static or bronchograms can be
- 14:08tricky because they could be seen
- 14:10in both pneumonia and atelectasis,
- 14:12so you really have to correlate
- 14:15this finding to the clinical exam,
- 14:17and these are probably instances where
- 14:19you want to get a chest film as well,
- 14:23and together with the lung ultrasound you
- 14:25can make a more accurate interpretation
- 14:27of the ultrasound findings. In contrast,
- 14:30dynamic air bronchograms as seen here,
- 14:32which are reflected by fluid mucus,
- 14:34phlegm buildup within the
- 14:36bronchi and bronchioles.
- 14:37Are the most specific finding for
- 14:39pediatric pneumonia by lung ultrasound.
- 14:42However, the incidence of finding
- 14:44dinamico bronchograms is relatively low,
- 14:46but you can see here on this clip
- 14:48motion of the fluid filled bronchi
- 14:51and you can almost make out the airway
- 14:54tree and so this is a great example
- 14:57of what you would be looking for in
- 15:00terms of dynamic air bronchograms
- 15:02which have been found to be the most
- 15:06specific finding for pneumonia.
- 15:08Using lung ultrasound.
- 15:10Here we have a 6 year old with
- 15:14sickle cell disease and acute chest
- 15:17syndrome as seen by X ray.
- 15:20In order to have bibasilar airspace
- 15:23opacities and of course the differential
- 15:26would be pneumonia versus atelectasis
- 15:29versus vaso occlusive changes by ultrasound.
- 15:33You can see a pleural disruption
- 15:36and shred sign in both the right
- 15:39and the left posterior lung fields.
- 15:42The pathology on the right is
- 15:44somewhat smaller.
- 15:45Here you can see towards the right
- 15:48of the screen the diaphragm,
- 15:50the double line of the diaphragm
- 15:53with the liver right below it and you
- 15:57can see disruption and shred of the
- 16:00pleura with B lines that are diving down.
- 16:04From the pleural interface and so
- 16:06the lesion on the left is actually
- 16:09much much bigger.
- 16:11There you don't see that clear,
- 16:13crisp pleura that echogenic
- 16:15line between the rib spaces.
- 16:17Because there is tissue consolidation
- 16:19there instead.
- 16:20So the shred sign is actually far
- 16:23lower on the screen about where
- 16:26the four centimeter marker is,
- 16:28and this is correlated with the X
- 16:31ray that appeared to be far worse.
- 16:34On the left compared to the right.
- 16:39And here we have a 12 year old with asthma
- 16:42who also presented with respiratory distress,
- 16:46found to have pneumonia by X ray and
- 16:48on lung ultrasound. You can see a
- 16:51clear hepatization of the lung tissue.
- 16:53So the probe in this case is a phased
- 16:56array probe which is placed in the
- 16:59left anterior zone above the heart.
- 17:02As you can see on the ultrasound image
- 17:05the heart is beating on the right side.
- 17:08And what appears to be liver above it.
- 17:12But in fact this is diseased lung
- 17:15tissue which would be reflective
- 17:17of more advanced pneumonia.
- 17:20So lines are missing.
- 17:21And because the disease process is
- 17:24parenchymal and not solely at the level
- 17:27of the alveolae or the interstitium,
- 17:30you do not see any B lines on this image
- 17:34but just advanced lung tissue consolidation.
- 17:38Otherwise known as Hepatization because
- 17:41of the similarities in appearance
- 17:43when comparing this to the normal
- 17:46appearance of liver by ultrasound.
- 17:51So we don't know what the future
- 17:54impact of lung focus will be.
- 17:57I believe there are three potential outcomes,
- 18:00one with integration of the clinical exam.
- 18:03We hope that pediatric pneumonia
- 18:06diagnosis can become more reliable.
- 18:08Ideally, we can make a earlier
- 18:10diagnosis and reduce the overall
- 18:13burden of chest radiography.
- 18:15Another potential impact is over
- 18:18prescription of antibiotics as.
- 18:20There's no way to fees abli or reliably
- 18:23differentiate a viral pneumonia from
- 18:26a bacterial pneumonia by ultrasound.
- 18:29And finally,
- 18:30there's a possibility that we may
- 18:33actually prescribe less antibiotics.
- 18:35Given again,
- 18:36the limitations in the physical
- 18:38exam and lack of reliability
- 18:41that X ray has to differentiate
- 18:44a viral from bacterial process.
- 18:49So this would be an example of the
- 18:52first outcome, greater position
- 18:53and more accurate diagnosis.
- 18:55So 6 year old male with Hemoglobin SC
- 18:58presented with fever for two days and
- 19:01shortness of breath on exam had some
- 19:03slight elevation in the heart rate,
- 19:06but otherwise normal oxygen saturation
- 19:08exam with wheezing and diminished
- 19:10breath sounds on the left side.
- 19:12High typical work up was done for SC disease
- 19:15with fever to include a chest X ray and.
- 19:19Lab work which revealed no
- 19:21Leukocytosis on the X ray.
- 19:24There was no acute cardio
- 19:26thoracic abnormality as per
- 19:28the radiologist interpretation.
- 19:32However, by lung focus there is clear
- 19:36shred sign in the left posterior
- 19:39lung field with disruption of
- 19:42the pleura and beelines emanating
- 19:45from this jagged pleural edge.
- 19:48This patient was subsequently admitted
- 19:51with early recognition of acute
- 19:53chest on given ceftriaxone and is it
- 19:56through myosin as per our hematology
- 19:59treatment recommendations and
- 20:00incurred a three day hospitalization?
- 20:03How luckily did not require any
- 20:06PRBC transfusion and had multiple
- 20:08negative blood cultures.
- 20:09This case was several years before we
- 20:12were routinely obtaining procalcitonin to
- 20:15help rid stratified bacterial versus viral.
- 20:18Pneumonia and a viral swab is not
- 20:20performed as his patient was managed
- 20:22in the hospital who did well and
- 20:24completed his course for community
- 20:26acquired pneumonia as an outpatient.
- 20:31Here's another example of how we may
- 20:34provide more efficient care with lung pocus.
- 20:37So in this clinical case,
- 20:39a 9 month old presented with
- 20:42respiratory distress, and this was the
- 20:443rd ER visit for the same illness.
- 20:47Had a prior rhinovirus positive
- 20:49tests in an X ray,
- 20:51which during the first visit was
- 20:53more in keeping with Perihilar and
- 20:56peribronchial interstitial markings,
- 20:58likely viral airway inflammation.
- 21:00Most likely bronchiolitis, however,
- 21:02ongoing fevers cough and some
- 21:04posts of emesis and increasing
- 21:05work of breathing and there was
- 21:08strong family history of asthma.
- 21:10This infant was takach Arctic with
- 21:12takip NIA and exam was notable for
- 21:14attractions and coarse breath sounds,
- 21:16but no audible wheezes were present,
- 21:18and the clinical team not only
- 21:20did a long ultrasound,
- 21:22but performed a cardiac ultrasound
- 21:23as well to rule out any other
- 21:26potential causes of compensated shock.
- 21:31So interestingly, this infant had one
- 21:34specific lung area of abnormality
- 21:36in the left posterior lung field.
- 21:39You can see here between those ribs.
- 21:43There is an absence of that
- 21:46pleural line and shred sign,
- 21:48so we have a lesion that is certainly
- 21:51abnormal and needs more thorough evaluation.
- 21:57So a scan performed on the opposite side,
- 22:01the right posterior lung field
- 22:03is here as a comparison,
- 22:05and you can see the intact pleura throughout.
- 22:10Spaces and. There are essentially normal
- 22:15a lines in the different lung zone.
- 22:18As the probe slides from the top
- 22:20of the patient down towards the
- 22:23diaphragm in a sagittal plane.
- 22:27And so we go back to the left side and
- 22:31get another clear look here at this sub,
- 22:35pleural abnormality,
- 22:36where there's a break in the pleural line.
- 22:40There's a shed sign and there are
- 22:43static air bronchograms in this lesion,
- 22:46demarcated by the arrow.
- 22:48And So what you do here is you
- 22:52turn the probe 90 degrees to try
- 22:54and assess a complete picture.
- 22:57Of this lesion, so when the probe
- 23:00is rotated in a transverse plane,
- 23:03you essentially see a confluence
- 23:06of beelines dropping down from the
- 23:09pleura as on the second ultrasound
- 23:11clip here and again.
- 23:13If you were to rotate it 90 degrees
- 23:16with the indicator towards the
- 23:19patient's head in a sagittal plane,
- 23:22you would have made out this abnormal
- 23:25consolidation which is highly suggestive.
- 23:28Of a pneumonia.
- 23:31So the clinical course was interesting
- 23:34for this infant was admitted for
- 23:36respiratory monitoring after
- 23:38initiation of hydros amoxicillin for
- 23:41this long ultrasound finding and X
- 23:43ray at the time was not obtained and
- 23:46had a pretty brief hospitalization.
- 23:48Had no fever, antibiotics ended up
- 23:50being a discontinued and was discharged
- 23:53home after some period of monitoring,
- 23:55which he seemed to do quite well.
- 24:01Then three days later, he came back,
- 24:04this now being the 4th ER visit with
- 24:07persistent fever and respiratory distress,
- 24:09at which point in X ray was repeated,
- 24:13showing bilateral findings concerning
- 24:15for pneumonia and amoxicillin was re
- 24:18prescribed and able to be discharged home,
- 24:20and he actually did quite well
- 24:23without any further emergency
- 24:24visits for labored breathing.
- 24:29OK, so the next possible outcome is that
- 24:32lung focus has the potential to lead to
- 24:35the prescription of more antibiotics.
- 24:38And I say this only because it is far
- 24:40more sensitive to pick up abnormalities
- 24:43when compared to X ray and viral
- 24:46pneumonia findings and bacterial
- 24:48pneumonia findings will have overlapped
- 24:50and this has been well documented
- 24:53to date with all the non specific
- 24:56findings we see with COVID pneumonia.
- 24:59Here in this case,
- 25:00we present a 27 month old with respiratory
- 25:03distress and fever in January 2020,
- 25:06when COVID pneumonia may have been
- 25:09circulating in the community.
- 25:10We don't know for 100%
- 25:13the symptoms consisted of.
- 25:16Two to three weeks of cough worse
- 25:18at night and one day a fever.
- 25:21Ah was ill appearing on exam
- 25:23with tachycardia,
- 25:23low oxygen saturation and takip NIA.
- 25:25Also was listless with flaring
- 25:27and accessory muscle use and
- 25:28diminished breath sounds throughout,
- 25:30but perhaps were sitting in the right
- 25:32upper lung field and the next rate
- 25:34is shown showed no focal infiltrate.
- 25:40Lang Focus performed in the right upper
- 25:42lobe showed the following abnormality.
- 25:45Disruption of the pleura,
- 25:47shred sign belines and this lesion was
- 25:51measured to be 1 1/2 centimeter and
- 25:54concerning for the start of a pneumonia.
- 26:00So this channel is emitted to the
- 26:02ICU and IBM PASILAN was initiated
- 26:05was treated with Bipap and required
- 26:07continuous albuterol and steroids.
- 26:10Interestingly, a procalcitonin test
- 26:11came back normal chest X ray done.
- 26:14The subsequent date revealed and was
- 26:16read as a right upper lobe infiltrate
- 26:19consolidation versus atelectasis,
- 26:20and this correlated perfectly with the area
- 26:23of the lung that was imaged the day before.
- 26:27With that abnormal finding.
- 26:29Had a three day hospitalization.
- 26:32Was managed as a bronchiolitis,
- 26:35a therapy with treatment of
- 26:38reactive bronchospasm and all
- 26:40viral tests were negative,
- 26:42so this child improved fully without
- 26:46completing a full course of antibiotics.
- 26:50And finally,
- 26:51lung ultrasound may have the potential
- 26:53to decrease antibiotic overuse.
- 26:55So here's a great example of a
- 26:5810 month old male with a fever
- 27:01and suspected pneumonia,
- 27:02as per clinicians that are referring
- 27:05hospital who had initiated amoxicillin
- 27:07with an X ray obtained was read
- 27:10as haziness in the left lung zone.
- 27:13Suspicious for pneumonia.
- 27:14However,
- 27:15there are definitely some other
- 27:17things going on clinically to include
- 27:20a prior COVID positive PCR test
- 27:2210 days before this presentation
- 27:24and daily fever for four days.
- 27:27Popular rash on the torso.
- 27:29Some lesions to the lip,
- 27:31gums,
- 27:31and some swelling to the hands and
- 27:34feet so multisystem picture and this
- 27:37infant actually looked quite well
- 27:39appearing and no respiratory distress.
- 27:42Playful and unremarkable
- 27:43physical examination,
- 27:44and you can see the labs there had a
- 27:47little thrombocytosis and a slight.
- 27:50Elevation in the ESR and the CRP.
- 27:56So in the PDE complete 6 zone,
- 27:59longer sound was performed and well
- 28:02tolerated and it revealed essentially the
- 28:05following findings which run remarkable.
- 28:08You can see a lines throughout all
- 28:12the lung zones being interrogated,
- 28:15and occasionally there's a little divot
- 28:18at the level of the pleura, but no true.
- 28:23B line with stacked,
- 28:25horizontal reverberation dipping down all
- 28:28the way down to the bottom of the screen.
- 28:31No shred sign.
- 28:33No static air bronchograms,
- 28:34and certainly no signs of hepatization.
- 28:37So based on these findings we
- 28:39actually made the recommendation
- 28:41to discontinue the amoxicillin.
- 28:46And this little infant was actually
- 28:49somewhat fascinating as it seemed to
- 28:52have some sort of mild inflammatory
- 28:55picture with a slightly elevated
- 28:58BNP and a slightly elevated D dimer
- 29:01was admitted for surveillance with
- 29:03concern for MIC normal echocardiogram
- 29:06during the admission, and there was
- 29:09no progression or decompensation,
- 29:11so the team was able to.
- 29:14The first steroids and IVIG.
- 29:17And had a great follow up visit
- 29:1910 days later with normalization
- 29:21of the inflammatory markers and
- 29:23was clinically well appearing and
- 29:26back to herself at this point.
- 29:31So there's lots of further inquiry that
- 29:34is necessary so that we can fine tune
- 29:37how to integrate lung pocus as part of
- 29:41our workups for pediatric pneumonia.
- 29:43And it's possible that we will have to
- 29:46incorporate long ultrasound findings
- 29:48with not only physical exam but also
- 29:51some laboratory values to make good
- 29:54decisions about antibiotic stewardship.
- 29:56And there's also some instances
- 29:58where lung ultrasound.
- 30:00Will have to be incorporated in
- 30:02parallel with chest radiography
- 30:04in certain instances to minimize
- 30:06our risk for misdiagnosis.
- 30:11And so here in this final case you can
- 30:15see we have a 21 year old with fever,
- 30:18wheezing and decreased
- 30:19breath sounds on the right.
- 30:21On this frontal projection of the X ray,
- 30:24you can see that there is an
- 30:26obvious abnormality that could
- 30:28be interpreted as pneumonia.
- 30:30If you put the lung probe as was done
- 30:33in this case, right over this lesion,
- 30:35you can see a mass like finding which
- 30:38could be misconstrued as hepatization.
- 30:40There is no lines.
- 30:42There are no body lines.
- 30:44There is no shred sign.
- 30:46There is no static air bronchograms
- 30:49and this tissue doesn't quite look
- 30:51hypothesized like in the prior example.
- 30:54So if you're up to obtain
- 30:57a lateral chest X ray,
- 30:59this diagnosis is more consistent
- 31:01with the anterior mediastinal mass,
- 31:03and this young man was subsequently
- 31:06diagnosed with a lymphoma.
- 31:07So the important point here
- 31:10is that a chest wall mass.
- 31:13We can mimic potentially the
- 31:15appearance of hepatocytes lung tissue,
- 31:17and this needs to be carefully
- 31:19accounted for during the clinical
- 31:21assessment of our patients.
- 31:25A couple of other pitfalls and
- 31:28potential false positives in the right
- 31:31clinical scenario, sinus can appear.
- 31:35Is a homogeneous you know appearing mass
- 31:39typically is this is found anteriorly.
- 31:44In front of the heart and can be seen.
- 31:47In my experience both on the right side
- 31:50and in the left side of the chest with
- 31:53integration of the anterior lung fields.
- 31:56So we must be able to recognize thymus
- 31:58tissue as normal and actually one
- 32:01of the keys for me is the plural.
- 32:04So in this image of thymus you
- 32:06can still make out the echogenic
- 32:08bright pleura in between the rib
- 32:11spaces and so that to me is a clear
- 32:14indicator that this is not consistent.
- 32:17With long hair participation or pneumonia.
- 32:21Finally, in the left upper quadrant,
- 32:24especially when assessing for.
- 32:27A fusion with the curvilinear probe,
- 32:30the stomach, when it is filled
- 32:32with mixed content to include air,
- 32:34can give off a bright echogenic appearance.
- 32:37So you really want to be very
- 32:39clear as to whether these findings
- 32:42are above or below the diaphragm.
- 32:44So in this particular image you're
- 32:46not seeing the diaphragm clearly,
- 32:48but you're seeing pleura at the
- 32:51top of the screen,
- 32:52next to the P with the lung sliding.
- 32:55And so you see, pleura rib pleura.
- 32:58Read you don't quite see the diaphragm,
- 33:01but the spleen.
- 33:02Is there,
- 33:03UM,
- 33:03right adjacent to the rib shadow
- 33:05that is in the center of the screen
- 33:08and the stomach with airfield and
- 33:11mixed contents is giving off a
- 33:13bright appearance behind this plane.
- 33:16So location, location,
- 33:17location and pattern recognition
- 33:18and knowing your landmarks and what
- 33:21you're looking for are going to
- 33:23be very important to minimize your
- 33:25false positive interpretations.
- 33:29So this is such an exciting modality,
- 33:32but we're clearly not doing this
- 33:34protocolized on every patient,
- 33:36and there are lots of reasons why this is so.
- 33:40Number one from a practical standpoint,
- 33:42it takes time, which it takes a longer
- 33:45time for the setup and the process
- 33:47of completing a high quality long
- 33:50ultrasound in a infant and a toddler as
- 33:53opposed to an X ray is just a quick.
- 33:58Picture with a plate on the
- 33:59back or on the side.
- 34:01Patient cooperation does come into play here,
- 34:04so you really have to.
- 34:07Engage, you know the caregiver
- 34:09to be a partner, and you know,
- 34:12sometimes you know.
- 34:13Patients just are not going to
- 34:16tolerate either the gel or the probe,
- 34:19or just the whole process in general and
- 34:23we need adequate training and we need to
- 34:26reach a level of competency across the
- 34:30board that is not yet been well established.
- 34:33And unfortunately,
- 34:34when doing research around this topic.
- 34:37There are serious challenges related
- 34:40to assigning an incontrovertible
- 34:42referenced or criterion standard,
- 34:43but for resource limited settings and
- 34:46for individuals who are comfortable
- 34:48at performing lung ultrasound and
- 34:51are able to interpret findings
- 34:53in the clinical context,
- 34:55this is an invaluable tool with tremendous
- 34:58promise for the future care of our
- 35:01pediatric patients with respiratory
- 35:03distress or unexplained chest pain,
- 35:06and there is certainly a lot of enthusiasm.
- 35:10And momentum behind for lung pocus
- 35:13to increase our position in emergency
- 35:16medicine when we are challenged to make
- 35:19clinical decisions with oftentimes
- 35:22imperfect and limited information.
- 35:28This concludes our introduction
- 35:30to lung ultrasound Part 2.
- 35:32We hope you find this
- 35:35information useful and.
- 35:36If there are any questions,
- 35:38please don't hesitate to reach out,
- 35:40otherwise we will see you
- 35:41soon and this content will be
- 35:43updated as deemed necessary.