The rate of venous thromboembolism, which is composed primarily of deep venous thrombosis and pulmonary embolism, is increasing in children. Advances in medical care, improved survival of children with life-threatening or chronic diseases, and increased awareness contribute to the increasing rate. Venous thromboembolism is potentially preventable in children, as it is in adults. However, paucity of pediatric data has limited the ability to prevent these events from occurring in children.
The goal of the PEITHO Program is to develop evidence-based strategies that will prevent venous thromboembolism in children. The program is dedicated to conducting innovative pediatric multicenter observational studies that define the epidemiology of venous thromboembolism, and interventional trials of preventive approaches against venous thromboembolism.