Erica Spatz, MD, MHS
Associate Professor of Cardiology and Associate Professor of Epidemiology (Chronic Diseases)Cards
About
Research
Publications
2025
Lipid-Lowering Therapy in the U.S. Adults Before and After the COVID-19 Pandemic
Essa M, Malik D, Lu Y, Yang H, Spatz E, Krumholz H, Faridi K. Lipid-Lowering Therapy in the U.S. Adults Before and After the COVID-19 Pandemic. JACC Advances 2025, 4: 101872. PMID: 40513221, PMCID: PMC12205634, DOI: 10.1016/j.jacadv.2025.101872.Peer-Reviewed Original ResearchThe invisible costs of heart failure: a societal toll
Haynes N, Spatz E. The invisible costs of heart failure: a societal toll. European Heart Journal 2025, ehaf223. PMID: 40457992, DOI: 10.1093/eurheartj/ehaf223.Peer-Reviewed Original ResearchAccountable Care Organization Participation and Cardiovascular Care Quality
Spatz E, Oddleifson D, Kayani J, Gosch K, Jones P, Doshi R, Maddox T, Desai N. Accountable Care Organization Participation and Cardiovascular Care Quality. JAMA Cardiology 2025, 10: 545-554. PMID: 40172907, PMCID: PMC11966472, DOI: 10.1001/jamacardio.2025.0381.Peer-Reviewed Original ResearchConceptsMedicare Shared Savings ProgramMedicare Shared Savings Program Accountable Care OrganizationsAccountable care organizationsAccountable care organization participationOutpatient cardiology practicesImplantable cardioverter defibrillator useCare qualityDefibrillator useNon-ACO practicesCardiology practiceQuality measuresImprove care qualityPre-post cohort studyPractice participationBlood pressure controlGroup of Medicare beneficiariesShared Savings ProgramCoronary artery diseaseQuality performance scoresAssociated with differential changesTraditional Medicare patientsARB prescriptionCare organizationsAntiplatelet prescriptionArtery disease10-Year and 30-Year Risks of Cardiovascular Disease in the U.S. Population
Faridi K, Malik D, Essa M, Yang H, Spatz E, Krumholz H, Lu Y. 10-Year and 30-Year Risks of Cardiovascular Disease in the U.S. Population. Journal Of The American College Of Cardiology 2025, 85: 2239-2249. PMID: 40499978, DOI: 10.1016/j.jacc.2025.03.546.Peer-Reviewed Original ResearchConceptsRisk of cardiovascular diseaseAtherosclerotic CVDU.S. adultsU.S. populationHispanic adultsCardiovascular diseaseCVD riskLong-term riskNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyRisk of atherosclerotic CVDElevated 10-year riskLong-term risk of cardiovascular diseaseAdults aged >Nutrition Examination SurveyTotal cardiovascular diseaseRisk factor profileRisk of total cardiovascular diseaseSurvey-weighted prevalenceMiddle-aged adultsPrevent cardiovascular diseaseHeart failureExamination SurveyAge-standardizedBlack adultsPerspective on the Choice and Duration of Dual Antiplatelet Therapy Recommendations in the 2025 Acute Coronary Syndrome Management Guideline
Ko D, Al-Lamee R, Bikdeli B, Cohen D, Januzzi J, Sawano M, Spatz E, Chan You S. Perspective on the Choice and Duration of Dual Antiplatelet Therapy Recommendations in the 2025 Acute Coronary Syndrome Management Guideline. Journal Of The American College Of Cardiology 2025, 85: 2079-2082. PMID: 40467133, DOI: 10.1016/j.jacc.2025.04.045.Peer-Reviewed Original ResearchAssociation of SARS-CoV-2 With Health-related Quality of Life 1 Year After Illness Using Latent Transition Analysis
Wisk L, Gottlieb M, Chen P, Yu H, O’Laughlin K, Stephens K, Nichol G, Montoy J, Rodriguez R, Santangelo M, Gatling K, Spatz E, Venkatesh A, Rising K, Hill M, Huebinger R, Idris A, Willis M, Kean E, McDonald S, Elmore J, Weinstein R. Association of SARS-CoV-2 With Health-related Quality of Life 1 Year After Illness Using Latent Transition Analysis. Open Forum Infectious Diseases 2025, 12: ofaf278. PMID: 40496983, PMCID: PMC12150399, DOI: 10.1093/ofid/ofaf278.Peer-Reviewed Original ResearchCOVID-19-like illnessPoor physicalOptimal HRQoLHealth-related quality of life 1 yearHealth-related quality-of-lifeLatent transition analysisHealth-related qualityPatient-reported HRQoLQuality of life 1 yearFollow-up assessmentQuality-of-lifeLongitudinal registry studySuboptimal HRQoLInverse probability weightingMental HRQoLPhysical HRQoLOverall HRQoL.PROMIS-29HRQoL scoresSARS-CoV-2 testingHRQoL changesHRQoL classesHRQoLWell-being classesTested SARS-CoV-2Trends in Prevalence, Treatment, and Relationship of Metabolic Syndrome and Individual Components by Race/Ethnicity, 1999-2018
Lu Y, Li X, Liu Y, Caraballo C, Massey D, Mahajan S, Spatz E, Herrin J, Krumholz H. Trends in Prevalence, Treatment, and Relationship of Metabolic Syndrome and Individual Components by Race/Ethnicity, 1999-2018. JACC Advances 2025, 4: 101785. PMID: 40373521, PMCID: PMC12144450, DOI: 10.1016/j.jacadv.2025.101785.Peer-Reviewed Original ResearchLipid-lowering medication useRacial/ethnic disparitiesMedication useMetS prevalenceRacial/ethnic differencesHispanic individualsAge-standardized prevalence estimatesNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyBlack individualsPersistent racial/ethnic disparitiesFasting glucoseNutrition Examination SurveyRelationship of metabolic syndromeMetabolic syndromePrescription drug useNationally representative dataExamination SurveyMetS componentsWaist circumferenceEligible individualsTreatment gapRacial/ethnic subgroupsU.S. adultsPrevalence estimatesRacial and Ethnic Differences Among Patients Referred for Noninvasive Coronary Artery Disease Evaluation.
Wright CX, Spatz ES, Miller EJ, Feher A. Racial and Ethnic Differences Among Patients Referred for Noninvasive Coronary Artery Disease Evaluation. JACC Cardiovasc Imaging 2025, 18: 618-620. PMID: 40183731, DOI: 10.1016/j.jcmg.2025.01.017.Peer-Reviewed Original ResearchBlood Pressure Control—Many Paths, 1 Goal
Spatz E, Schwartz J, Frieden T. Blood Pressure Control—Many Paths, 1 Goal. JAMA Cardiology 2025, 10: 333-334. PMID: 39878963, DOI: 10.1001/jamacardio.2024.5278.Peer-Reviewed Original ResearchTRENDS IN RACIAL AND ETHNIC DISPARITIES IN ADVANCED CARDIOVASCULAR-KIDNEY-METABOLIC SYNDROME AMONG U.S. ADULTS: INSIGHTS FROM NHANES 2011-2020
Yang H, Huang C, Sawano M, Herrin J, Faridi K, Li Z, Spatz E, Krumholz H, Lu Y. TRENDS IN RACIAL AND ETHNIC DISPARITIES IN ADVANCED CARDIOVASCULAR-KIDNEY-METABOLIC SYNDROME AMONG U.S. ADULTS: INSIGHTS FROM NHANES 2011-2020. Journal Of The American College Of Cardiology 2025, 85: 608. DOI: 10.1016/s0735-1097(25)01092-7.Peer-Reviewed Original Research
Clinical Care
Overview
Erica Spatz, MD, MHS, is a general cardiologist who treats a variety of conditions that relate to the heart and circulatory system. In addition to emphasizing prevention to her patients, she is an active researcher who investigates ways to prevent heart attacks and strokes, so that more people can live long and healthy lives.
“The field of prevention is exciting. We are rapidly developing new ways of estimating people’s risk of future heart disease, and we have new medications and tools to reduce that risk,” says Dr. Spatz, who is especially interested in applying “precision medicine” to prevention. This is making conversations with patients in her practice more specific and less generic. “I am thinking, ‘What are the patient’s risk factors? What's unique about their biology, their genetics, and their biography? What are the aspects of their lives that may be contributing to cardiovascular risk or, on the contrary, promoting cardiovascular health? What might be the best strategies for reducing risk and improving their health outcomes?’ The onus is on us as clinicians, physicians, nurses, and pharmacists, to really understand the person before us.”
We need to be working at multiple levels to reduce heart disease, Spatz says. “We need strong policies and coordinated community efforts to promote healthier lifestyles and overall well-being. There is so much we can be doing to make ‘healthy’ the easy choice for our population. At the individual level, there is an opportunity to better capture the personalized biological factors, experiences, and behaviors that inform cardiovascular risk—through digital technology and surveys.”
Lifestyle changes are often considered the bedrock of preventing heart disease, and while this can be difficult for some people—especially if they are overwhelmed with other life challenges—small achievable goals go a long way, Dr. Spatz says. “I try to think about this from a lifelong perspective. Cardiovascular disease prevention is hard work and people can't be perfect all the time, so I try to find specific things people can work on as well as opportunities when this makes sense in a person's life. If I can help them to define a healthier path, then I think the ripple effects can be massive.”
In addition to caring for patients, Dr. Spatz serves as a clinical investigator for the Center for Outcomes Research & Evaluation (CORE), an organization at Yale School of Medicine that focuses on health care quality, where she researches individualized approaches to preventing and managing cardiovascular disease, health disparities across the health care system, and ways to engage patients as partners in their care. She also is a cofounder of Project Access-New Haven—a network of physicians, hospitals, and community organizations partnering to provide donated specialty care to underserved patients in New Haven.
Clinical Specialties
Fact Sheets
Heart Attack (Myocardial Infarction)
Learn More on Yale MedicineFamilial hypercholesterolemia
Learn More on Yale MedicineHypercholesterolemia (High Cholesterol)
Learn More on Yale MedicineCOVID-19
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Board Certifications
Cardiovascular Disease
- Certification Organization
- AB of Internal Medicine
- Latest Certification Date
- 2019
- Original Certification Date
- 2013
Yale Medicine News
News & Links
News
- June 30, 2025
Biomedical Research Saves Human Lives
- May 15, 2025Source: Medscape
Role of Inflammation in Heart Disease: What PCPs Should Know
- May 14, 2025Source: WTNH
National Blood Pressure Awareness Month: Knowing Your Numbers Can Be a Lifesaving Step Toward Better Heart Health
- April 21, 2025Source: The New York Times
Do You Really Need to Cool Down After a Workout?
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New Haven, CT 06520-8017
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