Christopher Gange, MD
Assistant Professor of Radiology and Biomedical ImagingCards
Contact Info
Cardiothoracic Radiology
20 York St, Dept of Radiology and Biomedical Imaging
New Haven, CT 06510
United States
Publications Overview
- 15 Publications
- 232 Citations
- 10 Yale Co-Authors
Additional Titles
Fellowship Director, Thoracic Radiology
Contact Info
Cardiothoracic Radiology
20 York St, Dept of Radiology and Biomedical Imaging
New Haven, CT 06510
United States
Publications Overview
- 15 Publications
- 232 Citations
- 10 Yale Co-Authors
Additional Titles
Fellowship Director, Thoracic Radiology
Contact Info
Cardiothoracic Radiology
20 York St, Dept of Radiology and Biomedical Imaging
New Haven, CT 06510
United States
Publications Overview
- 15 Publications
- 232 Citations
- 10 Yale Co-Authors
About
Titles
Assistant Professor of Radiology and Biomedical Imaging
Fellowship Director, Thoracic Radiology
Biography
Having made stops in Boston, Philadelphia, and Rochester, I am starting my career as a diagnostic radiologist at Yale-New Haven Hospital. Radiology encompasses many of my favorite things, as I have always been interested in new technology, science, and healthcare. Every day, I use medical knowledge and technology to solve mysteries by making diagnoses
Appointments
Radiology & Biomedical Imaging
Assistant ProfessorPrimary
Other Departments & Organizations
- Cardiothoracic Radiology
- Program for Innovation in Imaging Informatics
- Radiology & Biomedical Imaging
- Yale Medicine
Education & Training
- Thoracic Radiology Fellow
- Brigham and Women's Hospital (2018)
- Radiology Resident
- University of Rochester - Strong Memorial Hospital (2017)
- Intern
- Drexel Univ - Hahnemann Hospital (2013)
- MD
- Drexel University, Medicine (2012)
- MMS
- Drexel University, Medical Science (2008)
- BS
- Boston University, Biomedical Engineering
Research
Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0002-1224-4665
Research at a Glance
Yale Co-Authors
Publications Timeline
Babina Gosangi, MD MPH
Ami Rubinowitz, MD
Anna Shlionsky Bader, MD, MS
Leah Traube
Daniel Boffa, MD
Gavitt Woodard, MD
Publications
2024
Next-generation digital chest tomosynthesis
Gange C, Ku J, Gosangi B, Liu J, Maolinbay M. Next-generation digital chest tomosynthesis. Journal Of Clinical Imaging Science 2024, 14: 22. PMID: 38975057, PMCID: PMC11225395, DOI: 10.25259/jcis_4_2024.Peer-Reviewed Original ResearchConceptsRadiation doseLow dose chest CTLung phantomLung nodulesEffective radiation dosePlane resolutionLow radiation doseLow dose CTPhantomSimulated pulmonary nodulesChest CTChest radiologistsHealthy volunteersPulmonary nodulesDose CTAnatomical locationNodule detectionImaging characteristicsTomosynthesisNodulesLungDoseDetect lung nodulesDevicesPotential utility
2023
Brief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans
Woodard G, Udelsman B, Prince S, Blasberg J, Dhanasopon A, Gange C, Traube L, Mase V, Boffa D, Detterbeck F, Bader A. Brief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans. JTO Clinical And Research Reports 2023, 4: 100583. PMID: 38074773, PMCID: PMC10709040, DOI: 10.1016/j.jtocrr.2023.100583.Peer-Reviewed Original ResearchConceptsGround-glass nodulesChest CT scanCT scanLung lesionsHealth systemLarge academic health systemAcademic health systemCross-sectional imagingRadiographic findingsPhysician consultationChest CTDatabase reviewTomography scanRadiographic lesionsAge groupsLesionsStudy periodLung nodulesOutpatient CTRadiology reportsAdult chestCTScansChestNodulesCardiothoracic complications of immune checkpoint inhibitors
Gosangi B, Wang Y, Rubinowitz A, Kwan J, Traube L, Gange C, Bader A. Cardiothoracic complications of immune checkpoint inhibitors. Clinical Imaging 2023, 102: 98-108. PMID: 37659356, DOI: 10.1016/j.clinimag.2023.08.001.Peer-Reviewed Educational MaterialsMeSH Keywords and ConceptsConceptsImmune checkpoint inhibitorsICI therapyCheckpoint inhibitorsOverall survivalTumor responseAdverse effectsDevelopment of irAEsNovel adverse effectsImproved overall survivalOverall patient outcomesICI administrationHematologic malignanciesPatient outcomesSolid tumorsIrAEsCancer treatmentGreater mortalityComplicationsTherapySurvivalInhibitorsMyocarditisPneumonitisPatientsMalignancy
2022
Diseases of the pulmonary arteries: imaging appearances and pearls
Cortopassi IO, Gosangi B, Asch D, Bader AS, Gange CP, Rubinowitz AN. Diseases of the pulmonary arteries: imaging appearances and pearls. Clinical Imaging 2022, 91: 111-125. PMID: 36067656, DOI: 10.1016/j.clinimag.2022.08.018.Peer-Reviewed Educational MaterialsMeSH Keywords and ConceptsConceptsContrast-enhanced chest CTChest X-rayPulmonary arteryEnlarged pulmonary arteryPulmonary vascular pathologyPulmonary artery anatomyEveryday clinical practiceAsymptomatic patientsImaging findingsPulmonary vasculatureArtery anatomyChest CTUrgent treatmentMediastinal structuresVascular pathologyArteryClinical practicePhysiologic dataEntire thoraxVessel wallPatientsDetailed evaluationPathologyWide spectrumQuantification of flowEarly-stage COVID-19 pandemic observations on pulmonary embolism using nationwide multi-institutional data harvesting
Wismüller A, DSouza AM, Abidin AZ, Ali Vosoughi M, Gange C, Cortopassi IO, Bozovic G, Bankier AA, Batra K, Chodakiewitz Y, Xi Y, Whitlow CT, Ponnatapura J, Wendt GJ, Weinberg EP, Stockmaster L, Shrier DA, Shin MC, Modi R, Lo HS, Kligerman S, Hamid A, Hahn LD, Garcia GM, Chung JH, Altes T, Abbara S, Bader AS. Early-stage COVID-19 pandemic observations on pulmonary embolism using nationwide multi-institutional data harvesting. Npj Digital Medicine 2022, 5: 120. PMID: 35986059, PMCID: PMC9388980, DOI: 10.1038/s41746-022-00653-2.Peer-Reviewed Original ResearchConceptsNatural language processingImage analysis serviceRadiology reportsSoftware infrastructureService requestsData harvestingAnalysis servicesLanguage processingCommercial AIGround truthManual reviewNLP accuracyExploratory toolResult dataComputed tomography pulmonary angiogramAIHealthcare systemPulmonary embolismInfrastructureRequestsEarly COVID-19 pandemicPE casesServicesAccuracyProcessingStandardizing the Reporting of Incidental, Non-Lung Cancer (Category S) Findings Identified on Lung Cancer Screening Low-Dose CT Imaging
Tanoue LT, Sather P, Cortopassi I, Dicks D, Curtis A, Michaud G, Bader A, Gange C, Detterbeck F, Killam J. Standardizing the Reporting of Incidental, Non-Lung Cancer (Category S) Findings Identified on Lung Cancer Screening Low-Dose CT Imaging. CHEST Journal 2022, 161: 1697-1706. PMID: 35032477, DOI: 10.1016/j.chest.2021.12.662.Peer-Reviewed Educational MaterialsMeSH Keywords and ConceptsConceptsLung cancer screeningCancer screeningIncidental findingAmerican CollegeLung cancer screening studyLung CT Screening ReportingRelevant specialty societiesLung nodulesCancer screening studyLow-dose CT scansPreventive health maintenanceStandardization of reportingLung cancerS findingsCancer findingsPatient distressLDCT scansCT scanPositive findingsHealth maintenanceCT imagingStandardized reportingSpecialty societiesScreening studyPotential harm
2021
COVID-19 ARDS: a review of imaging features and overview of mechanical ventilation and its complications
Gosangi B, Rubinowitz AN, Irugu D, Gange C, Bader A, Cortopassi I. COVID-19 ARDS: a review of imaging features and overview of mechanical ventilation and its complications. Emergency Radiology 2021, 29: 23-34. PMID: 34698956, PMCID: PMC8545770, DOI: 10.1007/s10140-021-01976-5.Peer-Reviewed Educational MaterialsMeSH Keywords and ConceptsConceptsAcute respiratory distress syndromeCOVID-19 acute respiratory distress syndromePulmonary interstitial emphysemaMechanical ventilationPathophysiology of ARDSVentilator-associated lung injuryCOVID-19Invasive mechanical ventilationRespiratory distress syndromeCOVID-19 pneumoniaHyaline membrane formationIntra-alveolar pressureMost COVID-19 casesImaging of patientsFeatures of complicationsAlveolar epithelial barrierBlood oxygen levelTension cystsLung injuryAlveolar ruptureDistress syndromeInterstitial emphysemaAlveolar edemaCOVID-19 casesInterstitial edema
2020
Social Distancing with Portable Chest Radiographs During the COVID-19 Pandemic: Assessment of Radiograph Technique and Image Quality Obtained at 6 Feet and Through Glass
Gange CP, Pahade JK, Cortopassi I, Bader AS, Bokhari J, Hoerner M, Thomas KM, Rubinowitz AN. Social Distancing with Portable Chest Radiographs During the COVID-19 Pandemic: Assessment of Radiograph Technique and Image Quality Obtained at 6 Feet and Through Glass. Radiology Cardiothoracic Imaging 2020, 2: e200420. PMID: 33778645, PMCID: PMC7673079, DOI: 10.1148/ryct.2020200420.Peer-Reviewed Original ResearchImaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 1: Cardiovascular Etiologies
Bader AS, Rubinowitz AN, Gange CP, Bader EM, Cortopassi IO. Imaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 1: Cardiovascular Etiologies. The American Journal Of Medicine 2020, 133: 1033-1038. PMID: 32442507, DOI: 10.1016/j.amjmed.2020.04.024.Peer-Reviewed Educational MaterialsMeSH Keywords and ConceptsConceptsChest painPrimary care settingCardiovascular etiologyCare settingsCommon presenting complaintPrimary care physiciansMultiple organ systemsPresenting complaintCare physiciansPainNumerous imaging modalitiesOrgan systemsImaging modalitiesEtiologyAppropriate testsCliniciansFindingsPhysiciansSettingComplaintsImaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 2: Sources of Noncardiac Chest Pain
Bader AS, Rubinowitz AN, Gange CP, Bader EM, Cortopassi IO. Imaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 2: Sources of Noncardiac Chest Pain. The American Journal Of Medicine 2020, 133: 1135-1142. PMID: 32442508, DOI: 10.1016/j.amjmed.2020.04.013.Peer-Reviewed Educational MaterialsMeSH Keywords and ConceptsMeSH KeywordsChest PainEsophageal Motility DisordersFractures, CompressionGastroesophageal RefluxHernia, HiatalHumansMagnetic Resonance ImagingMusculoskeletal DiseasesPleural EffusionPneumoniaPneumothoraxPrimary Health CareRadiography, ThoracicRespiratory Tract DiseasesRib FracturesSpinal FracturesThoracic WallTietze's SyndromeTomography, X-Ray ComputedConceptsChest painPrimary care settingCare settingsNoncardiac chest painCommon presenting complaintPrimary care physiciansMultiple organ systemsNoncardiac sourcesPresenting complaintCare physiciansMusculoskeletal etiologyRadiologic appearancePainNumerous imaging modalitiesOrgan systemsImaging modalitiesAppropriate testsEtiologyCliniciansFindingsPhysiciansSettingComplaints
Clinical Care
Overview
Christopher Gange Jr., MD, is a diagnostic radiologist who specializes in thoracic oncology. He reads chest X-rays, CT scans, and MRIs for patients at Yale New Haven Hospital and outpatient centers throughout Connecticut.
“I work every day to improve the diagnosis of cancer, infection, and other lung diseases,” Dr. Gange says. “Radiology encompasses many of my favorite things, as I have always been interested in new technology, science, and health care. I love technology and using it to help people.”
Dr. Gange is also interested in informatics and applying new technology to improve the accuracy and efficiency of lung imaging. He is involved in research that focuses on using machine learning tools to expedite the reading of chest CTs and X-rays, and creating data registries to improve research on lung cancer and infections. “Recently, my focus also has shifted to the COVID-19 pandemic. I was part of teams that created data registries of COVID patient imaging data and worked to validate a new method to more safely perform portable chest X-rays,” he says.
But his best moments are, “when I read a cancer staging follow-up study and the cancer has improved,” he says. It’s also rewarding when his work contributes to an early diagnosis. He tells patients, “Don't put those follow-up scans off. Even if the news is not exactly what you wanted to hear, it is always best to know as soon as possible.”
Clinical Specialties
Board Certifications
Diagnostic Radiology
- Certification Organization
- AB of Radiology
- Original Certification Date
- 2018
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Contacts
Cardiothoracic Radiology
20 York St, Dept of Radiology and Biomedical Imaging
New Haven, CT 06510
United States