2025
Cost Efficiency of fMRI Studies Using Resting‐State Vs. Task‐Based Functional Connectivity
Zhang X, Hulvershorn L, Constable T, Zhao Y, Wang S. Cost Efficiency of fMRI Studies Using Resting‐State Vs. Task‐Based Functional Connectivity. Human Brain Mapping 2025, 46: e70260. PMID: 40543060, PMCID: PMC12182254, DOI: 10.1002/hbm.70260.Peer-Reviewed Original ResearchConceptsNeuroimaging studiesNeuropsychological outcomesFMRI conditionsGradual-onset continuous performance taskCognitive control outcomesN-back memory taskContinuous performance taskNegative emotional outcomesFMRI taskMemory taskFMRI studyPerformance tasksTask conditionsEmotional outcomesFMRITaskFunctional fingerprintsPower differentialsSociabilityOutcomesControl outcomesIdentifying dynamic reproducible brain states using a predictive modelling approach
O’Connor D, Horien C, Mandino F, Constable R. Identifying dynamic reproducible brain states using a predictive modelling approach. Imaging Neuroscience 2025, 3: imag_a_00540. DOI: 10.1162/imag_a_00540.Peer-Reviewed Original ResearchMoment-to-moment changesBrain statesConnectome-based predictive modelingContinuous performance taskBrain-based modelsFunctional connectivity analysisModel of traitsFMRI-based functional connectivityDynamic functional connectivity analysisInternal mental processesFunctional connectivity mapsFunctional connectivity modelsLeft-out dataFMRI scanningPersonality traitsFunctional connectivityPerformance tasksConnectivity analysisScanning sessionMental processesModels of behaviorBrain-statesBrainConnectivity mapsTrait-based predictions
2024
Robust Brain Correlates of Cognitive Performance in Psychosis and Its Prodrome
Ward H, Beermann A, Xie J, Yildiz G, Felix K, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Seidman L, Stone W, Tsuang M, Walker E, Woods S, Coleman M, Bouix S, Holt D, Öngür D, Breier A, Shenton M, Heckers S, Halko M, Lewandowski K, Brady R. Robust Brain Correlates of Cognitive Performance in Psychosis and Its Prodrome. Biological Psychiatry 2024, 97: 139-147. PMID: 39032726, PMCID: PMC11634655, DOI: 10.1016/j.biopsych.2024.07.012.Peer-Reviewed Original ResearchAuditory continuous performance taskConnectome-wide association studiesEarly psychosisCognitive performanceNorth American Prodrome Longitudinal Study 2At-risk individualsCorrelates of cognitive performanceBrain-cognition relationshipsBrain-phenotype relationshipsBrain-behavior associationsContinuous performance taskEarly-course psychosisLongitudinal Study 2Resting-state fMRIProspective study of individualsHuman Connectome ProjectPsychosis onsetStudy of individualsPsychosisStudy 2Performance tasksNeurocognitive impairmentCognitive instrumentsHealthy participantsRobust associations
2019
Dynamic sustained attention markers differentiate atypical development: The case of Williams syndrome and Down's syndrome
Shalev N, Steele A, Nobre A, Karmiloff-Smith A, Cornish K, Scerif G. Dynamic sustained attention markers differentiate atypical development: The case of Williams syndrome and Down's syndrome. Neuropsychologia 2019, 132: 107148. PMID: 31323245, PMCID: PMC6891877, DOI: 10.1016/j.neuropsychologia.2019.107148.Peer-Reviewed Original ResearchConceptsSustained attentionWilliams syndromeDown syndromeContinuous performance taskImpaired sustained attentionAttention deficit symptomsMeasure sustained attentionSpecificity to changesAtypical developmentDeficit symptomsBehavioral disordersPerformance tasksAttention markerPoor functional outcomeCase of Williams syndromePoor performanceInvestigate similaritiesChildrenTaskAttentionDisordersFunctional outcomesDownElements of performanceSymptomsDissociable Catecholaminergic Modulation of Visual Attention: Differential Effects of Catechol-O-Methyltransferase and Dopamine Beta-Hydroxylase Genes on Visual Attention
Shalev N, Vangkilde S, Neville M, Tunbridge E, Nobre A, Chechlacz M. Dissociable Catecholaminergic Modulation of Visual Attention: Differential Effects of Catechol-O-Methyltransferase and Dopamine Beta-Hydroxylase Genes on Visual Attention. Neuroscience 2019, 412: 175-189. PMID: 31195057, PMCID: PMC6645579, DOI: 10.1016/j.neuroscience.2019.05.068.Peer-Reviewed Original ResearchConceptsContinuous performance taskSustained attentionVisual attentionAttentional functionsAttentional selectionPerformance tasksEffects of catechol-O-methyltransferaseGo/No-Go taskDopamine beta-hydroxylase geneBehaviorally relevant visual informationThreshold of visual perceptionCatechol-O-methyltransferaseResponse inhibitionGo/No-GoIgnoring distractionsGenotype statusCatecholaminergic activityGroup differencesTask performanceRelevant visual informationGenes COMTBeta-hydroxylase geneCOMTDifferential effectsDopamine
2014
Adolescent nonsuicidal self-injury: Examining the role of child abuse, comorbidity, and disinhibition
Auerbach R, Kim J, Chango J, Spiro W, Cha C, Gold J, Esterman M, Nock M. Adolescent nonsuicidal self-injury: Examining the role of child abuse, comorbidity, and disinhibition. Psychiatry Research 2014, 220: 579-584. PMID: 25095754, PMCID: PMC4252370, DOI: 10.1016/j.psychres.2014.07.027.Peer-Reviewed Original ResearchConceptsNonsuicidal Self-InjuryCorrelates of nonsuicidal self-injuryComputerized continuous performance taskPatterns of nonsuicidal self‐injuryChild abuseConsistent with study hypothesesStructured Clinical InterviewContinuous performance taskSelf-report questionnairesAssociated with comorbiditySelf-injuryPsychiatric comorbidityClinical InterviewChildhood abuseMental disordersPerformance tasksPrevalence of child abuseDisinhibitionAbuseComorbidityStudy hypothesesParticipantsChildrenPotential importanceResidential units
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