2022
Controversies in enhanced recovery after cardiac surgery
Shaw A, Guinn N, Brown J, Arora R, Lobdell K, Grant M, Gan T, Engelman D. Controversies in enhanced recovery after cardiac surgery. Perioperative Medicine 2022, 11: 19. PMID: 35477446, PMCID: PMC9047268, DOI: 10.1186/s13741-022-00250-7.Peer-Reviewed Original ResearchCardiac surgeryEnhanced recoveryStandardized perioperative careAcute kidney injuryGoal-directed therapyPatient blood managementEvidence-based best practicesSignificant evidence gapsAnalgesic reductionKidney injuryOverall morbidityPerioperative carePatient-centric carePreventable morbidityMyocardial protectionBlood managementOperative techniqueEvidence gapsPerioperative medicineSurgeryOperating roomQuality InitiativeMorbidityMortalitySignificant controversy
2020
Using near-infrared spectroscopy myocardial oximetry to monitor myocardial oxygen balance in a swine model of cardiac surgery: a descriptive study
Honikman R, Pawale A, Itagaki S, Lin H, Rodriguez-Diaz C, Weiss A, Fischer G, Weiner M. Using near-infrared spectroscopy myocardial oximetry to monitor myocardial oxygen balance in a swine model of cardiac surgery: a descriptive study. Journal Of Clinical Monitoring And Computing 2020, 35: 1367-1380. PMID: 33169311, DOI: 10.1007/s10877-020-00610-y.Peer-Reviewed Original ResearchConceptsAdequacy of myocardial protectionCoronary sinus bloodCardiac surgeryTissue oximetryHemoglobin oxygen saturationMyocardial protectionSinus bloodCoronary sinus blood samplesCardiac surgical practiceCoronary occlusionOxygen supply-demand mismatchAdministration of isoproterenolDecreased coronary blood flowDelivery of cardioplegiaCoronary blood flowMyocardial oxygen supplyMyocardial oxygen balanceSaturation of oxygenVentricular pacingBlood hypoxemiaSurgical practiceBlood flowHemoglobin saturation of oxygenBlood samplesSwine model
2005
Simultaneous Antegrade/Retrograde Normothermic Perfusion with Blood (Beating Heart) for Aortic Root Replacement in Acute Type‐A Dissection of the Aorta
Di Luozzo G, Panos AL, Lombardi P, Salerno TA. Simultaneous Antegrade/Retrograde Normothermic Perfusion with Blood (Beating Heart) for Aortic Root Replacement in Acute Type‐A Dissection of the Aorta. Journal Of Cardiac Surgery 2005, 20: 350-352. PMID: 15985136, DOI: 10.1111/j.1540-8191.2005.200463.x.Peer-Reviewed Original ResearchMild Hypothermia Impairs Left Ventricular Diastolic but Not Systolic Function
Fischer U, Cox C, Laine G, Mehlhorn U, Allen S. Mild Hypothermia Impairs Left Ventricular Diastolic but Not Systolic Function. Journal Of Investigative Surgery 2005, 18: 291-296. PMID: 16319049, DOI: 10.1080/08941930500327047.Peer-Reviewed Original ResearchConceptsPreload recruitable stroke workSystolic functionCardiopulmonary bypassCardiac outputCardioplegic arrestBody temperatureEarly post-CPB periodPost-CPB periodImpact of hypothermiaLeft ventricular functionRecruitable stroke workDP/Ventricular diastolicDiastolic functionCardiac dysfunctionVentricular functionLV diastolicHYPO groupCPB periodMyocardial protectionAnesthetized dogsMild hypothermiaStroke workLV micromanometerBaseline levels
2004
Myocardial Protection in Reoperative Coronary Artery Bypass Grafting:
Fazel S, Borger M, Weisel R, Cohen G, Pelletier M, Rao V, Yau T. Myocardial Protection in Reoperative Coronary Artery Bypass Grafting:. Journal Of Cardiac Surgery 2004, 19: 291-295. PMID: 15245456, DOI: 10.1111/j.0886-0440.2004.4052_11.x.Peer-Reviewed Original ResearchConceptsCoronary Artery Bypass GraftingRedo Coronary Artery Bypass GraftingArtery Bypass GraftingBypass GraftingFirst-time coronary artery bypass graftingMyocardial protectionReoperative coronary artery bypass graftingAssociated with high morbidityMyocardial protection techniquesReoperative coronary surgeryRedo CABG patientsCoronary surgeryCABG patientsHigh morbidityRetrograde cardioplegiaIncreased riskMyocardial infarction
2003
Beeinflusst die Myokardprotektion während koronarer Bypassoperationen die klinischen Patientenergebnisse?
Südkamp M, Mehlhorn U, Fattah M, Reza Raji M, Fischer U, Kuhn-Régnier F, Geissler H, de Vivie E. Beeinflusst die Myokardprotektion während koronarer Bypassoperationen die klinischen Patientenergebnisse? Zeitschrift Für Herz-,Thorax- Und Gefäßchirurgie 2003, 17: 64-68. DOI: 10.1007/s00398-003-0387-z.Peer-Reviewed Original ResearchCoronary artery surgeryConventional cardioplegiaArtery surgeryMyocardial protectionRenal failureNeurological symptomsIntensive care unit stayPerioperative myocardial infarction ratePreoperative left ventricular functionRoutine coronary artery surgeryTotal hospital stayΒ-blocker esmololPostoperative renal failureMyocardial infarction rateContinuous coronary perfusionLeft ventricular functionMyocardial protection techniquesIntensive care unitMechanical circulatory supportPositive inotropic medicationTime of mobilizationCardioplegia techniqueHospital mortalityUnit stayHospital stay
2001
Impact of myocardial protection during coronary bypass surgery on patient outcome
Mehlhorn U, Fattah M, Kuhn-Régnier F, Südkamp M, Geissler H, Raji M, Fischer U, de Vivie E. Impact of myocardial protection during coronary bypass surgery on patient outcome. Vascular 2001, 9: 482-486. PMID: 11489654, DOI: 10.1016/s0967-2109(01)00024-2.Peer-Reviewed Original ResearchConceptsCoronary artery surgeryConventional cardioplegiaArtery surgeryMyocardial protectionRenal failureNeurological symptomsPatient outcomesUltra-short acting beta-blocker esmololIntensive care unit stayPerioperative myocardial infarction ratePreoperative left ventricular functionRoutine coronary artery surgeryBeta-blocker esmololTotal hospital stayPostoperative renal failureCoronary bypass surgeryMyocardial infarction rateContinuous coronary perfusionLeft ventricular functionMyocardial protection techniquesIntensive care unitMechanical circulatory supportPositive inotropic medicationTime of mobilizationCardioplegia techniqueImpact of Myocardial Protection during Coronary Bypass Surgery on Patient Outcome
Mehlhorn U, Fattah M, Kuhn-Régnier F, Südkamp M, Geissler H, Raji M, Fischer U, de Vivie E. Impact of Myocardial Protection during Coronary Bypass Surgery on Patient Outcome. Vascular 2001, 9: 482-486. DOI: 10.1177/096721090100900513.Peer-Reviewed Original ResearchCoronary artery surgeryConventional cardioplegiaArtery surgeryMyocardial protectionRenal failureNeurological symptomsPatient outcomesIntensive care unit stayPerioperative myocardial infarction ratePreoperative left ventricular functionRoutine coronary artery surgeryTotal hospital stayPostoperative renal failureCoronary bypass surgeryMyocardial infarction rateContinuous coronary perfusionLeft ventricular functionMyocardial protection techniquesIntensive care unitMechanical circulatory supportPositive inotropic medicationTime of mobilizationCardioplegia techniqueHospital mortalityUnit staySingle-clamp technique does not protect against cerebrovascular accident in coronary artery bypass grafting⋆
Kim R, Mariconda D, Tellides G, Kopf G, Dewar M, Lin Z, Elefteriades J. Single-clamp technique does not protect against cerebrovascular accident in coronary artery bypass grafting⋆. European Journal Of Cardio-Thoracic Surgery 2001, 20: 127-132. PMID: 11423285, DOI: 10.1016/s1010-7940(01)00765-5.Peer-Reviewed Original ResearchConceptsSingle-clamp techniqueCoronary artery bypassPostoperative strokeArtery bypassStroke preventionCerebrovascular accidentSide-biting aortic clampAdverse myocardial effectsCross-clamp timePostoperative adverse eventsPerioperative myocardial infarctionCoronary bypass operationsLogistic regression analysisEmbolic consequencesHospital mortalityAdverse eventsAortic clampMyocardial effectsBypass operationMyocardial infarctionMyocardial protectionClinical practiceClamp techniqueSecond surgeonStroke
1998
Topical Hypothermia: Ineffective and Deleterious as Adjunct to Cardioplegia for Myocardial Protection
Nikas D, Ramadan F, Elefteriades J. Topical Hypothermia: Ineffective and Deleterious as Adjunct to Cardioplegia for Myocardial Protection. The Annals Of Thoracic Surgery 1998, 65: 28-31. PMID: 9456090, DOI: 10.1016/s0003-4975(97)01261-7.Peer-Reviewed Original ResearchConceptsCold blood cardioplegiaFirst postoperative dayTopical hypothermiaPostoperative dayPulmonary complicationsDiaphragmatic paralysisSystemic hypothermiaBlood cardioplegiaGroup AGroup BIced slushMyocardial protectionIntermittent cold blood cardioplegiaGroup B. Group AAdditional cardioprotective benefitNonrandomized consecutive patientsPhrenic nerve paralysisPostoperative cardiac morbidityCoronary artery bypassLow cardiac outputPerioperative myocardial infarctionCoronary bypass patientsB. Group ASignificant differencesInotrope use
1988
Myocardial Protection During Percutaneous Transluminal Coronary Angioplasty
Lasala J, Cleman M. Myocardial Protection During Percutaneous Transluminal Coronary Angioplasty. Cardiology Clinics 1988, 6: 329-343. PMID: 2977571, DOI: 10.1016/s0733-8651(18)30481-8.Peer-Reviewed Original Research
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