2009
Early On–Cardiopulmonary Bypass Hypotension and Other Factors Associated With Vasoplegic Syndrome
Levin M, Lin H, Castillo J, Adams D, Reich D, Fischer G. Early On–Cardiopulmonary Bypass Hypotension and Other Factors Associated With Vasoplegic Syndrome. Circulation 2009, 120: 1664-1671. PMID: 19822810, DOI: 10.1161/circulationaha.108.814533.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassPoor clinical outcomesArterial blood pressure curveArterial pressureVasoplegic syndromeClinical outcomesAdult cardiac surgery casesBlood pressure curvePredictor of poor clinical outcomePost-CPB hematocritAngiotensin-converting enzyme inhibitorsCardiac surgery casesPost-CPB periodMean arterial pressurePredictors of patientsLength of bypassLength of stayClinically significant declineAdditive EuroSCOREPreoperative useVasodilatory shockBeta-blockersIntraoperative useSurgery casesProcedure type
2005
Mild Hypothermia Impairs Left Ventricular Diastolic but Not Systolic Function
Fischer U, Cox C, Laine G, Mehlhorn U, Allen S. Mild Hypothermia Impairs Left Ventricular Diastolic but Not Systolic Function. Journal Of Investigative Surgery 2005, 18: 291-296. PMID: 16319049, DOI: 10.1080/08941930500327047.Peer-Reviewed Original ResearchConceptsPreload recruitable stroke workSystolic functionCardiopulmonary bypassCardiac outputCardioplegic arrestBody temperatureEarly post-CPB periodPost-CPB periodImpact of hypothermiaLeft ventricular functionRecruitable stroke workDP/Ventricular diastolicDiastolic functionCardiac dysfunctionVentricular functionLV diastolicHYPO groupCPB periodMyocardial protectionAnesthetized dogsMild hypothermiaStroke workLV micromanometerBaseline levels
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