2025
Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids
Becker W, Seal K, Nelson D, DeRonne B, Kats A, Morasco B, Frank J, Makris U, Painter J, Allen K, Mixon A, Bohnert A, Reznik T, Hagedorn H, Hammett P, Borsari B, Baxley C, Krebs E. Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids. JAMA Internal Medicine 2025, 185: 372-381. PMID: 39960730, PMCID: PMC11833656, DOI: 10.1001/jamainternmed.2024.8361.Peer-Reviewed Original ResearchThis study assessed whether switching chronic pain patients from high-dose opioids to buprenorphine improved pain or reduced opioid use, finding no improvements compared with not offering the switch.EP6.47 Pericapsular Nerve Group Block Effectively Controls Pain After Hip Arthroscopy: A Systematic Review
Kothari T, Qureshi A, Rodriguez G, Lee M, MacLeod J, Pettinelli N, Rosa R, Park N, Gillinov S, Moran J, Norman M, Jimenez A. EP6.47 Pericapsular Nerve Group Block Effectively Controls Pain After Hip Arthroscopy: A Systematic Review. Journal Of Hip Preservation Surgery 2025, 12: i104-i105. PMCID: PMC11954087, DOI: 10.1093/jhps/hnaf011.336.Peer-Reviewed Original ResearchPericapsular nerve group blockPericapsular nerve groupPost-anesthesia care unitPain scoresCochrane Center Register of Controlled TrialsAnalgesic consumptionHip arthroscopySystematic reviewOpioid consumptionPreferred Reporting Items of Systematic ReviewsItems of Systematic ReviewsAverage VAS pain scoreMorphine Milligram EquivalentsPostoperative pain scoresPreferred Reporting ItemsVAS pain scoresAge of patientsEffective analgesic techniquePrimary research articlesControl groupRegister of Controlled TrialsAnterior hip capsuleAnesthesia care unitMilligram equivalentsPENG blockAnalgesic Quality Improvement in Paravertebral Blocks for Pediatric Nuss Procedure: An Exploratory Report on the Effects of Perineural Combined Glucocorticoids
Donham R, Jin E, Caty M, Thomas D, Yuan C, Hollingsworth K, Zhang X, Yanez N, Li J. Analgesic Quality Improvement in Paravertebral Blocks for Pediatric Nuss Procedure: An Exploratory Report on the Effects of Perineural Combined Glucocorticoids. Journal Of Pain Research 2025, 18: 489-496. PMID: 39895814, PMCID: PMC11784254, DOI: 10.2147/jpr.s502600.Peer-Reviewed Original ResearchPostoperative opioid consumptionContinuous thoracic paravertebral blockMorphine Milligram EquivalentsThoracic paravertebral blockParavertebral blockOpioid consumptionNuss procedureDexamethasone sodium phosphateCombined glucocorticoidPain scoresDecreased postoperative opioid consumptionOral morphine milligram equivalentsMethylprednisolone acetateContinuous paravertebral blockPostoperative opioid usagePectus excavatum repairReview of patientsHospital length of stayAcademic children's hospitalLength of stayOpioid usageMilligram equivalentsElectronic health record reviewPlain ropivacaineWound dehiscence
2024
Opioid Prescribing Trends Following Lumbar Discectomy.
Rancu A, Gouzoulis M, Winter A, Katsnelson B, Ansah-Twum J, Grauer J. Opioid Prescribing Trends Following Lumbar Discectomy. Journal Of The American Academy Of Orthopaedic Surgeons 2024 PMID: 39706160, DOI: 10.5435/jaaos-d-24-00908.Peer-Reviewed Original ResearchMorphine Milligram EquivalentsOpioid prescriptionsLumbar diskectomyElixhauser Comorbidity IndexComorbidity indexPrescribing patternsAssociated with prescribing opioidsPrescribed morphine milligram equivalentsDiagnosis of chronic painMedian morphine milligram equivalentsSame-day diagnosisProportion of patientsOpioid prescribing trendsPatterns of opioidsPrescribing patterns of opioidsDiagnosis of neoplasmsAssociated with lower ageMultivariate regression analysisMilligram equivalentsPrescribed opioidsLumbar discectomySpine proceduresChronic painFemale sexPrescribing trendsBariatric surgery targeting opioid prescribing: a national model for effectively reducing opioid use after bariatric surgery
Petrick A, Shah T, Gadaleta D, Gould J, Morton J, Smith A, Evans-Labok K, Knapp L, Ko C, Brethauer S. Bariatric surgery targeting opioid prescribing: a national model for effectively reducing opioid use after bariatric surgery. Surgery For Obesity And Related Diseases 2024, 21: 402-410. PMID: 39753417, DOI: 10.1016/j.soard.2024.11.011.Peer-Reviewed Original ResearchMedian morphine milligram equivalentsOpioid useBariatric surgeryOpioid prescriptionsOpioid prescribingPrescription opioidsMBSAQIP-accredited centersOpioid naive patientsOutpatient opioid useChronic opioid usersChronic opioid useInpatient opioid useMorphine Milligram EquivalentsBariatric Surgery AccreditationReduce opioid prescribingOpioid-related deathsMilligram equivalentsOpioid usersPrescription habitsOpioidSurgeryProtocol adherenceInpatient stayPrescription guidelinesBariatricOpioid Use Following Open Reduction and Internal Fixation of Mandibular Fractures
Rancu A, Salib A, Kammien A, Lizardi J, Allam O, Grauer J, Alperovich M. Opioid Use Following Open Reduction and Internal Fixation of Mandibular Fractures. Journal Of Craniofacial Surgery 2024, 36: 503-507. PMID: 39601551, DOI: 10.1097/scs.0000000000010930.Peer-Reviewed Original ResearchMorphine Milligram EquivalentsMandible fracturesProportion of patientsOpioid useOpioid prescriptionsInternal fixationInternal fixation of mandibular fracturesPrescribing patternsFixation of mandibular fracturesMedian morphine milligram equivalentsHistory of chronic painOpioid Prescribing PatternsDecreased proportion of patientsPost-fractureDays post-fractureLong bone fracturesTraumatic craniofacial injuriesMilligram equivalentsMandibular fracturesPrescribed narcoticsPostoperative painChronic painCraniofacial injuriesOpen reductionOpioid117. Opioid prescription patterns following single-level lumbar discectomy: a national database study
Rancu A, Gouzoulis M, Winter A, Katsnelson B, Ansah-Twum J, Grauer J. 117. Opioid prescription patterns following single-level lumbar discectomy: a national database study. The Spine Journal 2024, 24: s60-s61. DOI: 10.1016/j.spinee.2024.06.560.Peer-Reviewed Original ResearchMorphine Milligram EquivalentsSingle-level lumbar discectomyMedian morphine milligram equivalentsOpioid prescriptionsLumbar discectomyPrescribed morphine milligram equivalentsDiagnosis of chronic painPostoperative opioid prescriptionsOpioid Prescribing PatternsOpioid prescription patternsPostoperative pain controlPostoperative pain managementProportion of patientsNational database studyMultivariate linear regression analysisWilcoxon rank sum testDiagnosis of neoplasmsMultivariate logistic regressionRank sum testExcess opioidsPrescription percentageMilligram equivalentsPostoperative opioidsChronic painSpine proceduresThe Association of Surgical Setting With Opioid Prescribing Patterns Following Wide-Awake Trigger Finger Release
Kammien A, Shvedova M, Allam O, Prsic A, Grauer J, Colen D. The Association of Surgical Setting With Opioid Prescribing Patterns Following Wide-Awake Trigger Finger Release. Annals Of Plastic Surgery 2024, 93: e45-e49. PMID: 38984645, DOI: 10.1097/sap.0000000000004030.Peer-Reviewed Original ResearchPerioperative opioid prescriptionMorphine Milligram EquivalentsOpioid prescriptionsPain controlSurgical settingPostoperative painOffice-based surgeryOperating roomMultivariate analysisPerception of postoperative painOpioid Prescribing PatternsPostoperative pain controlReducing opioid prescriptionsNational administrative claims databaseElixhauser comorbidity index scoreChronic back/neck painHand surgeryComorbidity Index scoreAdministrative claims databaseMonitored Anesthesia CareMilligram equivalentsPostoperative dataPrescribed opioidsPerioperative opioidsPreoperative dataThe Correlation of Surgical Setting With Perioperative Opioid Prescriptions for Wide-Awake Carpal Tunnel Release.
Kammien A, Hu K, Collar J, Rancu A, Zhao K, Grauer J, Colen D. The Correlation of Surgical Setting With Perioperative Opioid Prescriptions for Wide-Awake Carpal Tunnel Release. Hand 2024, 15589447241247247. PMID: 38654508, PMCID: PMC11571719, DOI: 10.1177/15589447241247247.Peer-Reviewed Original ResearchCarpal tunnel releasePerioperative opioid prescriptionOpioid prescriptionsAssociation of opioid prescriptionsSurgical settingOpioid utilizationPerioperative opioid utilizationMorphine Milligram EquivalentsAdministrative claims databaseOpioid dependence/abuseMilligram equivalentsPostoperative dataElixhauser Comorbidity IndexPain controlPreoperative dataBilateral surgeryTraditional anesthesiaBack/neck painMatched CohortOffice-based surgeryComorbidity indexMultivariate analysisOpioidSurgeryAnesthetic technique
2022
Race, Gender, and Primary Language Were Not Associated With Changes in Opioid Prescribing in Children: Results From a Single Institution, 2010 to 2020
Begley B, Cerniglia K, Aboelatta M, Begum L, Gilbert G, Mathew J, Meixner S, Franklin C, Ramirez R. Race, Gender, and Primary Language Were Not Associated With Changes in Opioid Prescribing in Children: Results From a Single Institution, 2010 to 2020. Clinical Orthopaedics And Related Research® 2022, 481: 338-344. PMID: 36125497, PMCID: PMC9831194, DOI: 10.1097/corr.0000000000002414.Peer-Reviewed Original ResearchConceptsMorphine Milligram EquivalentsPrescribed more medicationsAmount of opiatesPatient ageOpioid prescribingAmount of pain medicationPrimary languageOpioid prescription amountsYear of treatmentWilcoxon rank sum testLong-bone fracturesTime of admissionPediatric orthopaedic populationRank sum testTime of dischargeAssociation of ageChi-square testMilligram equivalentsPain medicationHospital discharge recordsOpiate prescriptionPrescribed opiatesTwo-part model analysisSingle institutionsExtremity fractures
2021
Postdischarge Pain and Opioid Use After Cardiac Surgery: A Prospective Cohort Study
Percy E, Hirji S, Leung N, Harloff M, Newell P, Cherkasky O, McGurk S, Yazdchi F, Cook R, Pelletier M, Kaneko T. Postdischarge Pain and Opioid Use After Cardiac Surgery: A Prospective Cohort Study. The Annals Of Thoracic Surgery 2021, 115: 1526-1532. PMID: 34979139, DOI: 10.1016/j.athoracsur.2021.12.007.Peer-Reviewed Original ResearchConceptsOpioid useCardiac surgeryOpioid consumptionRate of chronic opioid useOxycodone 5-mg tabletsPredictive of opioid useMedian total consumptionChronic opioid useMorphine Milligram EquivalentsPatterns of opioid consumptionMonths of surgeryProspective cohort studyConsecutive patientsMilligram equivalentsCardiac operationsHistory of substance useNonhome facilityPostdischarge painPill countDays of dischargePain managementCohort studyOpioidSurgeryPatient diaries
2020
Variability in opioid prescribing practices among cardiac surgeons and trainees
Percy E, Hirji S, Cote C, Laurin C, Atkinson L, Kiehm S, Malarczyk A, Harloff M, Bozso S, Buyting R, Hassanabad A, Guo M, Jaffer I, Lodewyks C, Tam D, Tremblay P, Légaré J, Cook R, Kaneko T, Pelletier M. Variability in opioid prescribing practices among cardiac surgeons and trainees. Journal Of Cardiac Surgery 2020, 35: 2657-2662. PMID: 32720337, DOI: 10.1111/jocs.14885.Peer-Reviewed Original ResearchConceptsDischarge opioid prescriptionsOpioid prescriptionsCardiac surgeonsCardiac surgeryCanadian Society of Cardiac SurgeonsOpioid epidemicMedian total doseMorphine Milligram EquivalentsOpioid prescribing practicesAssociated with opioid use disorderDose of medicationOpioid use disorderMilligram equivalentsPrescribed opioidsOpioid medicationsTotal doseOpioidPrescription practicesPrescribing habitsUse disorderInterquartile rangeLack of formal educationPrescribing practicesSurgerySurgeons
2014
Rules and values: a coordinated regulatory and educational approach to the public health crises of chronic pain and addiction.
Katzman J, Comerci G, Landen M, Loring L, Jenkusky S, Arora S, Kalishman S, Marr L, Camarata C, Duhigg D, Dillow J, Koshkin E, Taylor D, Geppert C. Rules and values: a coordinated regulatory and educational approach to the public health crises of chronic pain and addiction. American Journal Of Public Health 2014, 104: 1356-62. PMID: 24922121, PMCID: PMC4103251, DOI: 10.2105/ajph.2014.301881.Peer-Reviewed Original ResearchConceptsChronic painSurvey of knowledgeOverdose death ratesPublic health problemDrug overdose deathsPublic health crisisBoard of PharmacyDispensing dataSelf-EfficacyPrescribing cliniciansHealth problemsEducation programsMilligram equivalentsOverdose deathsOpioid addictionDeath ratePositive changesHealth crisisEducational approachPainPrescribingCliniciansAddictionNew MexicoConcomitant decline
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