2025
Resource use in infants undergoing esophageal atresia repair at major children's hospitals
Sescleifer A, Penikis A, Chidiac C, Salvi P, Sferra S, Engwall-Gill A, Solomon D, Kunisaki S. Resource use in infants undergoing esophageal atresia repair at major children's hospitals. Surgery 2025, 184: 109428. PMID: 40472454, DOI: 10.1016/j.surg.2025.109428.Peer-Reviewed Original ResearchEsophageal atresiaEsophageal atresia repairAtresia repairChildren's HospitalPediatric Health Information System databaseMedian costInstitutional surgical volumeConcomitant cardiac surgeryHospital costsHealth Information System databaseNeonatal surgical conditionsPostoperative respiratory morbidityAnastomotic leak rateMulticenter cohort studyMechanical ventilation daysManagement of esophageal atresiaMultivariate linear regression analysisAssociated with increased costsAssociated with increased hospital costsPrimary outcome measureClinical practice guidelinesCardiac surgeryPreoperative factorsTracheoesophageal fistulaSurgical management
2024
Costs of care during chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell lymphomas
Di M, Potnis K, Long J, Isufi I, Foss F, Seropian S, Gross C, Huntington S. Costs of care during chimeric antigen receptor T-cell therapy in relapsed or refractory B-cell lymphomas. JNCI Cancer Spectrum 2024, 8: pkae059. PMID: 39115391, PMCID: PMC11340641, DOI: 10.1093/jncics/pkae059.Peer-Reviewed Original ResearchChimeric antigen receptor T-cell therapyB-cell lymphomaRelapsed/refractory B-cell lymphomaT-cell therapyCAR-T administrationCAR-T productsMedian total costCommercially insured patientsReal-world costsMedian costOut-of-pocket copaymentsCost of careLymphomaMonthly costTherapyPatientsProduct acquisitionFinancial outcomesHigher upfront costImpact of comorbid opioid use disorder and major depressive disorder on healthcare utilization outcomes in patients with peripheral artery disease: A National Readmission Database analysis
Amenyedor K, Lee M, Algara M, Siddiqui W, Hardt M, Romain G, Mena-Hurtado C, Smolderen K. Impact of comorbid opioid use disorder and major depressive disorder on healthcare utilization outcomes in patients with peripheral artery disease: A National Readmission Database analysis. Vascular Medicine 2024, 29: 163-171. PMID: 38391134, DOI: 10.1177/1358863x241228540.Peer-Reviewed Original ResearchComorbid opioid use disorderOpioid use disorderPeripheral arterial diseaseDepressive disorderUse disorderArtery diseaseHealthcare utilization outcomesICD-9/10 diagnosis codesPain management strategiesMultivariate logistic regression modelNational Readmission DatabaseHierarchical multivariable logistic regression modelsLength of stayLogistic regression modelsMDDMedian stayPrimary outcomeHighest median costReadmissions DatabasePatientsMedian costStudy populationUtilization outcomesWeighted admissionsDiagnosis codes
2022
Primary care doctor and nurse consultations among people who live in slums: a retrospective, cross-sectional survey in four countries
Watson S, Bakibinga P, Kabaria C, Kasiira Z, Kibe P, Kyobutungi C, Mbaya N, Mberu B, Mohammed S, Njeri A, Azam I, Iqbal R, Nazish A, Rizvi N, Syed A, Ahmed S, Choudhury N, Alam O, Khan A, Rahman O, Yusuf R, Odubanjo D, Ayobola M, Fayehun O, Omigbodun A, Osuh M, Owoaje E, Taiwo O, Lilford R, Sartori J, Watson S, Diggle P, Aujla N, Chen Y, Conlan C, Gill P, Griffiths F, Harris B, Madan J, Muir H, Oyebode O, Pitidis V, de Albuquerque J, Smith S, Taylor C, Tregonning G, Ulbrich P, Uthman O, Wilson R, Yeboah G, Park J. Primary care doctor and nurse consultations among people who live in slums: a retrospective, cross-sectional survey in four countries. BMJ Open 2022, 12: e054142. PMID: 34996795, PMCID: PMC8744106, DOI: 10.1136/bmjopen-2021-054142.Peer-Reviewed Original ResearchConceptsConsultation ratesPrimary care consultation ratesPrimary care servicesHealth-seeking behaviorPrimary care doctorsCross-sectional surveyHospital outpatient departmentsMonthly total expenditureSecondary outcome measuresHigh-income countriesNurse consultantsCare doctorsCare servicesProvider typeMedian travel timeSlum sitesChild surveysChronic diseasesSlum populationTraditional healersProvidersOutpatient departmentMedian costVisit ratesVisits
2021
Brief report: Cannabis and opioid use disorder among heart failure admissions, 2008–2018
Chouairi F, Mullan CW, Ravindra N, Clark KAA, Jaffe EM, Bhinder J, Fuery M, Guha A, Ahmad T, Desai NR. Brief report: Cannabis and opioid use disorder among heart failure admissions, 2008–2018. PLOS ONE 2021, 16: e0255514. PMID: 34591847, PMCID: PMC8483306, DOI: 10.1371/journal.pone.0255514.Peer-Reviewed Original Research
2020
Cost of tuberculosis treatment in low- and middle-income countries: systematic review and meta-regression
Siapka M, Vassall A, Cunnama L, Pineda C, Cerecero D, Sweeney S, Bautista-Arredondo S, Bollinger L, Cameron D, Levin C, Gomez GB. Cost of tuberculosis treatment in low- and middle-income countries: systematic review and meta-regression. The International Journal Of Tuberculosis And Lung Disease 2020, 24: 802-810. PMID: 32912385, DOI: 10.5588/ijtld.19.0694.Peer-Reviewed Original ResearchConceptsMiddle-income countriesCost estimatesMonths of treatmentGross domestic productUpper middle-income countriesTreatment cost estimatesTB treatmentDomestic productTuberculosis treatmentMedian costSystematic reviewPriority settingMulti-level regression modelsUncertainty intervalsUnit costCost dataCost variationTreatmentDelivery modeGrey literatureCountriesPrimary dataRegression modelsCostHigh-quality primary dataPoor Cost Awareness Among Anesthesia Providers for Medications, Supplies, and Blood Products
Qin C, Merkel K, Yesantharao L, Lau E, Phelps M, Kajstura T, Grant M, Frank S, Cho B. Poor Cost Awareness Among Anesthesia Providers for Medications, Supplies, and Blood Products. The Joint Commission Journal On Quality And Patient Safety 2020, 46: 524-530. PMID: 32682692, DOI: 10.1016/j.jcjq.2020.06.007.Peer-Reviewed Original ResearchConceptsNon-opioid analgesiaBlood-related productsBlood productsAnesthesia providersProvider typeAcademic tertiary care hospitalTertiary care hospitalHigh-value health careAverage wholesale priceHypertension medicationsCare hospitalNeuromuscular blockersMedian costMedicationsPoor knowledgeHealth careVasopressorsAnalgesiaAwareness interventionAntibioticsCost awarenessProvidersPercentage of itemsTotal itemsOpioidsBenchmarking the value of care: Variability in hospital costs for common operations and its association with procedure volume.
Zogg CK, Bernard AC, Hirji SA, Minei JP, Staudenmayer KL, Davis KA. Benchmarking the value of care: Variability in hospital costs for common operations and its association with procedure volume. Journal Of Trauma And Acute Care Surgery 2020, 88: 619-628. PMID: 32039972, PMCID: PMC7802807, DOI: 10.1097/ta.0000000000002611.Peer-Reviewed Original ResearchConceptsLaparoscopic appendectomyLaparoscopic cholecystectomyHospital costsMeans of USMedian costProcedure volumeEmergency general surgeryTotal hospital costsMedian hospital costsNational Inpatient SampleAdults 18 yearsNational cost savingsAnnual procedure volumeValue of careHospital complicationsIndex hospitalHealth care valuePatient characteristicsAdverse outcomesInpatient SampleInclusion criteriaGeneral surgeryHospitalLevel IIICommon operationSignificant Improvement in the Value of Surgical Treatment of Tibial Plateau Fractures Through Surgeon Practice Standardization.
Kempton LB, Schneble CA, Brown K, Sorkin AT, Virkus WW. Significant Improvement in the Value of Surgical Treatment of Tibial Plateau Fractures Through Surgeon Practice Standardization. Journal Of The American Academy Of Orthopaedic Surgeons 2020, 28: 772-779. PMID: 31996608, DOI: 10.5435/jaaos-d-18-00720.Peer-Reviewed Original ResearchConceptsPartial articular fracturesComplete articular fracturesArticular fracturesGroup 2Group 1Clinical outcomesInjury characteristicsPhysical functionPatient outcomesSurgical careMedian costSurgical costsOutcomes Measurement Information System Physical FunctionMedian f/uMcMaster Universities Osteoarthritis IndexVisual analog pain scaleAnalog pain scaleSimilar patient outcomesProspective observational studyPROMIS PF scoresTibial plateau fracturesPain interference domainTibial plateau fracture fixationOsteoarthritis IndexPain scale
2017
Regional variation in the cost of infrainguinal lower extremity bypass surgery in the United States
Nejim B, Wang S, Arhuidese I, Obeid T, Alshaikh H, Aridi H, Locham S, Malas M. Regional variation in the cost of infrainguinal lower extremity bypass surgery in the United States. Journal Of Vascular Surgery 2017, 67: 1170-1180.e4. PMID: 29074114, DOI: 10.1016/j.jvs.2017.08.055.Peer-Reviewed Original ResearchMeSH KeywordsAgedChi-Square DistributionCost-Benefit AnalysisDatabases, FactualFemaleHealth ExpendituresHealthcare DisparitiesHospital CostsHumansLinear ModelsLower ExtremityMaleMiddle AgedModels, EconomicPeripheral Arterial DiseasePractice Patterns, Physicians'Process Assessment, Health CareRetrospective StudiesSurgeonsTreatment OutcomeUnited StatesVascular GraftingConceptsLower extremity bypassIn-hospital costsHospital factorsService-specific costsInfrainguinal lower extremity bypassHealth care expendituresMedian in-hospital costsGeneralized linear regression modelsLower extremity bypass surgeryHealth systemPeripheral arterial diseaseStandard revascularization proceduresPatient's clinical conditionIdentified adult patientsLinear regression modelsCare expendituresFinancial burdenRegional variationMedian costPatient demographicsClinical characteristicsAdult patientsBypass surgeryNortheast regionPatient characteristicsEffect of Hospital Ownership on Outcomes of Heart Failure Hospitalization
Akintoye E, Briasoulis A, Egbe A, Orhurhu V, Ibrahim W, Kumar K, Alliu S, Nas H, Levine D, Weinberger J. Effect of Hospital Ownership on Outcomes of Heart Failure Hospitalization. The American Journal Of Cardiology 2017, 120: 831-837. PMID: 28689752, DOI: 10.1016/j.amjcard.2017.06.009.Peer-Reviewed Original ResearchConceptsInpatient mortalityFemale patientsGovernment hospitalsHospitalization outcomesHospital ownershipSignificant differencesCharge of hospitalizationRoutine home dischargeHeart failure hospitalizationMean lengthNational Inpatient SampleCost of hospitalizationHF hospitalizationFailure hospitalizationHome dischargeHospital dischargeMale patientsInpatient SamplePrimary diagnosisProfit hospitalsHospitalizationMedian costMedian chargeMortality rateHospital
2016
Cost Differential of Chemotherapy for Solid Tumors.
Nadeem H, Jayakrishnan T, Rajeev R, Johnston F, Gamblin T, Turaga K, Nadeem H, Jayakrishnan T, Rajeev R, Johnston F, Gamblin T, Turaga K. Cost Differential of Chemotherapy for Solid Tumors. JCO Oncology Practice 2016, 12: e299-307, 251. PMID: 26860586, DOI: 10.1200/jop.2015.006700.Peer-Reviewed Original ResearchConceptsSolid tumorsCurative therapyNational Comprehensive Cancer Network guidelinesNational Comprehensive Cancer NetworkBreast cancer regimensCancer therapy regimensComprehensive Cancer NetworkCost of chemotherapyUS adult malesMetastatic cancer therapyCancer regimensChemotherapy regimensChemotherapeutic regimensTherapy regimensNetwork guidelinesBaseline drugRegimensChemotherapyTreatment periodCancer therapyCancer NetworkMedian costPractice patternsTumorTherapy
2015
Older Women With Localized Breast Cancer: Costs And Survival Rates Increased Across Two Time Periods
Feinstein AJ, Long J, Soulos PR, Ma X, Herrin J, Frick KD, Chagpar AB, Krumholz HM, Yu JB, Ross JS, Gross CP. Older Women With Localized Breast Cancer: Costs And Survival Rates Increased Across Two Time Periods. Health Affairs 2015, 34: 592-600. PMID: 25847641, DOI: 10.1377/hlthaff.2014.1119.Peer-Reviewed Original ResearchConceptsStage II diseaseStage III diseaseCancer-related costsCancer careBreast cancerMedian costSurvival rateEnd Results Program-MedicareFive-year survivalCancer care costsBreast surgerySurvival outcomesImproved outcomesOlder womenRadiation therapyCare costsStage IIDiseaseStudy periodWomenCancerCareSignificant national attentionOutcomesPercent
2014
Cost differential among systemic therapies for colon cancer.
Nadeem H, Jayakrishnan T, Gamblin T, Turaga K. Cost differential among systemic therapies for colon cancer. Journal Of Clinical Oncology 2014, 32: 583-583. DOI: 10.1200/jco.2014.32.3_suppl.583.Peer-Reviewed Original ResearchNational Comprehensive Cancer NetworkMetastatic colon cancerColon cancerTreatment of metastatic colon cancerNational Comprehensive Cancer Network guidelinesMedian costSystemic therapy regimensComprehensive Cancer NetworkChemotherapy regimensChemotherapeutic regimensSystemic therapyAdjuvant treatmentSystemic treatmentTherapy regimensAlternative chemotherapeutic strategiesToxicity profileChemotherapeutic strategiesRegimensAmerican patientsCancer NetworkTherapeutic benefitCancerHealth care costsReduce health care costsChemotherapy
2013
Minimally invasive oesophagectomy more expensive than open despite shorter length of stay†
Dhamija A, Dhamija A, Hancock J, McCloskey B, Kim AW, Detterbeck FC, Boffa DJ. Minimally invasive oesophagectomy more expensive than open despite shorter length of stay†. European Journal Of Cardio-Thoracic Surgery 2013, 45: 904-909. PMID: 24092502, DOI: 10.1093/ejcts/ezt482.Peer-Reviewed Original ResearchConceptsOpen transthoracicInvasive oesophagectomyOesophageal cancerHigher surgical expenseShorter hospital stayDay of surgeryTotal hospital costsGreater overall costsMIO groupMIO patientsSurgical expensesHospital stayOperative mortalityEntire hospitalizationTranshiatal approachInpatient hospitalizationHealth care economyOpen groupHospital costsShorter lengthInvasive approachTheatre costsBaseline statusInvasive proceduresMedian costF-089MINIMALLY INVASIVE OESOPHAGECTOMY MORE EXPENSIVE THAN OPEN AT NORTH AMERICAN HOSPITAL DESPITE SHORTER LENGTH OF STAY
Dhamija A, Dhamija A, Kim A, Detterbeck F, Boffa D. F-089MINIMALLY INVASIVE OESOPHAGECTOMY MORE EXPENSIVE THAN OPEN AT NORTH AMERICAN HOSPITAL DESPITE SHORTER LENGTH OF STAY. Interdisciplinary CardioVascular And Thoracic Surgery 2013, 17: s24-s24. DOI: 10.1093/icvts/ivt288.89.Peer-Reviewed Original Research
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