2020
P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study
Daffner S, Bunch J, An H, Burton D, Milam R, Park D, Strenge K, Whang P. P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study. The Spine Journal 2020, 20: s204. DOI: 10.1016/j.spinee.2020.05.520.Peer-Reviewed Original ResearchIliac crest bone graftFusion rateBone graft substituteClinical outcomesSpinal fusionOswestry Disability Index scoresProspective multicenter cohort studyAutologous iliac crest bone graftSTUDY DESIGN/SETTINGIndependent core labPosterolateral lumbar spinal fusionSF-36v2 PCSDisability Index scoresMulticenter cohort studyPosterolateral lumbar fusion surgeryProspective multicenter studyBetter clinical outcomesLumbar fusion surgeryCrest bone graftGold standard graft materialLumbar spinal fusionDESIGN/SETTINGStandard graft materialPosterolateral spinal fusionEndogenous growth factors
2014
Short-Term Adverse Events, Length of Stay, and Readmission After Iliac Crest Bone Graft for Spinal Fusion
Gruskay JA, Basques BA, Bohl DD, Webb ML, Grauer JN. Short-Term Adverse Events, Length of Stay, and Readmission After Iliac Crest Bone Graft for Spinal Fusion. Spine 2014, 39: 1718-1724. PMID: 24979140, DOI: 10.1097/brs.0000000000000476.Peer-Reviewed Original ResearchConceptsIliac crest bone graftLength of stayPostoperative blood transfusionAdverse eventsCrest bone graftReadmission ratesBlood transfusionOperative timeSpinal fusionMultivariate analysisICBG cohortBone graftRetrospective cohort studyShort-term morbidityTerm adverse eventsShort-term outcomesBone graft harvestBivariate logistic regressionDonor site morbidityDatabase cohortCohort studySurgical dataSurgical timeGraft harvestBACKGROUND DATA
2013
Only prolonged time from abstraction found to affect viable nucleated cell concentrations in vertebral body bone marrow aspirate
Badrinath R, Bohl DD, Hustedt JW, Webb ML, Grauer JN. Only prolonged time from abstraction found to affect viable nucleated cell concentrations in vertebral body bone marrow aspirate. The Spine Journal 2013, 14: 990-995. PMID: 24184640, DOI: 10.1016/j.spinee.2013.10.021.Peer-Reviewed Original ResearchConceptsBone marrow aspirateVertebral levelCell countMarrow aspiratesNucleated cell countNucleated cell concentrationFusion surgerySecond pedicleTraditional iliac crest bone graftLumbar instrumented fusion surgeryIliac crest bone graftInstrumented fusion surgeryStudy-specific conflictsCell viabilitySame vertebral levelCrest bone graftSpinal fusion surgeryEffect of lateralityRegular clinical useCortical graftsPerioperative conditionsOutcome measuresBone graftSpinal instrumentationAspirates
2012
Free Vascularized Iliac Crest Bone Graft for the Treatment of a Pediatric Lateral Humeral Condyle Fracture Nonunion
Chubb P, Oishi S, Lattanza L. Free Vascularized Iliac Crest Bone Graft for the Treatment of a Pediatric Lateral Humeral Condyle Fracture Nonunion. JBJS Case Connector 2012, 2: e63. PMID: 29252359, DOI: 10.2106/jbjs.cc.k.00125.Peer-Reviewed Original Research
2007
The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study
Vaccaro AR, Whang PG, Patel T, Phillips FM, Anderson DG, Albert TJ, Hilibrand AS, Brower RS, Kurd MF, Appannagari A, Patel M, Fischgrund JS. The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study. The Spine Journal 2007, 8: 457-465. PMID: 17588821, DOI: 10.1016/j.spinee.2007.03.012.Peer-Reviewed Original ResearchConceptsOP-1 PuttyUninstrumented fusionIliac crest autograftDegenerative spondylolisthesisOverall success rateAutograft patientsX-ray filmsAdverse eventsDecompressive laminectomyCrest autograftAutogenous boneShort Form Health Survey scoresForm Health Survey scoresBone graft substituteAutogenous iliac crest bone graftIliac crest bone graftPatient-reported outcome measuresPilot studyIntermediate-term efficacyOswestry Disability IndexPreoperative Oswestry scoreHealth Survey scoresPrimary efficacy endpointSF-36 scoresSymptomatic spinal stenosis
2001
Flexibility Analysis of Posterolateral Fusions in a New Zealand White Rabbit Model
Erulkar J, Grauer J, Patel T, Panjabi M. Flexibility Analysis of Posterolateral Fusions in a New Zealand White Rabbit Model. Spine 2001, 26: 1125-1130. PMID: 11413423, DOI: 10.1097/00007632-200105150-00006.Peer-Reviewed Original ResearchConceptsPosterolateral fusionRabbit modelAutogenous iliac crest bone graftIliac crest bone graftTime pointsNew Zealand white rabbitsPosterolateral lumbar fusionAdult New Zealand white rabbitsCrest bone graftNew Zealand white rabbit modelZealand white rabbitsHuman cadaveric studyPosterolateral spinal fusionWhite rabbit modelVivo rabbit modelIntertransverse process fusionLumbar fusionClinical studiesBACKGROUND DATASpinal fusionAnimal studiesCadaveric studyBone graftWhite rabbitsManual palpation
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