2016
Laminectomy plus Fusion versus Laminectomy Alone for Lumbar Spondylolisthesis
Ghogawala Z, Dziura J, Butler WE, Dai F, Terrin N, Magge SN, Coumans JV, Harrington JF, Amin-Hanjani S, Schwartz JS, Sonntag VK, Barker FG, Benzel EC. Laminectomy plus Fusion versus Laminectomy Alone for Lumbar Spondylolisthesis. New England Journal Of Medicine 2016, 374: 1424-1434. PMID: 27074067, DOI: 10.1056/nejmoa1508788.Peer-Reviewed Original ResearchConceptsPhysical component summary scoreDecompression-alone groupSF-36 physical component summary scoreFusion groupSummary scoresDecompressive laminectomySpinal stenosisGrade IOutcome measuresSpinal fusionOswestry Disability Index scoresSymptomatic lumbar spinal stenosisPhysical health-related qualityDegenerative grade IStable degenerative spondylolisthesisLonger hospital stayMore blood lossOswestry Disability IndexDisability Index scoresSecondary outcome measuresHealth-related qualityMedical Outcomes StudyPosterolateral instrumented fusionPrimary outcome measureLumbar spinal stenosis
2007
The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study
Vaccaro AR, Whang PG, Patel T, Phillips FM, Anderson DG, Albert TJ, Hilibrand AS, Brower RS, Kurd MF, Appannagari A, Patel M, Fischgrund JS. The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study. The Spine Journal 2007, 8: 457-465. PMID: 17588821, DOI: 10.1016/j.spinee.2007.03.012.Peer-Reviewed Original ResearchConceptsOP-1 PuttyUninstrumented fusionIliac crest autograftDegenerative spondylolisthesisOverall success rateAutograft patientsX-ray filmsAdverse eventsDecompressive laminectomyCrest autograftAutogenous boneShort Form Health Survey scoresForm Health Survey scoresBone graft substituteAutogenous iliac crest bone graftIliac crest bone graftPatient-reported outcome measuresPilot studyIntermediate-term efficacyOswestry Disability IndexPreoperative Oswestry scoreHealth Survey scoresPrimary efficacy endpointSF-36 scoresSymptomatic spinal stenosis
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