2020
P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study
Daffner S, Bunch J, An H, Burton D, Milam R, Park D, Strenge K, Whang P. P122. Use of a novel allograft in single- and two-level posterolateral lumbar spinal fusion: two-year clinical and radiographic results from a prospective multicenter study. The Spine Journal 2020, 20: s204. DOI: 10.1016/j.spinee.2020.05.520.Peer-Reviewed Original ResearchIliac crest bone graftFusion rateBone graft substituteClinical outcomesSpinal fusionOswestry Disability Index scoresProspective multicenter cohort studyAutologous iliac crest bone graftSTUDY DESIGN/SETTINGIndependent core labPosterolateral lumbar spinal fusionSF-36v2 PCSDisability Index scoresMulticenter cohort studyPosterolateral lumbar fusion surgeryProspective multicenter studyBetter clinical outcomesLumbar fusion surgeryCrest bone graftGold standard graft materialLumbar spinal fusionDESIGN/SETTINGStandard graft materialPosterolateral spinal fusionEndogenous growth factors
2010
Augmented demineralized bone matrix: a potential alternative for posterolateral lumbar spinal fusion.
Biswas D, Bible JE, Whang PH, Miller CP, Jaw R, Miller S, Grauer JN. Augmented demineralized bone matrix: a potential alternative for posterolateral lumbar spinal fusion. The American Journal Of Orthopedics 2010, 39: 531-8. PMID: 21623419.Peer-Reviewed Original ResearchConceptsFusion rateGraft alternativesPosterolateral lumbar spinal fusionLumbar spinal fusionRhBMP-2Spine fusion modelDose-response curveEctopic bone formation modelBone graft alternativesStudy ratsLumbar fusionRat modelSpinal fusionSpine fusionB graftsRecombinant human bone morphogenetic protein-2Manual palpationHuman bone morphogenetic protein-2Bone matrix productsSignificant differencesProtein 2DBM carrierBone matrixAutograftBone morphogenetic protein-2
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