2017
Electronic Health Data Predict Outcomes After Aneurysmal Subarachnoid Hemorrhage
Zafar SF, Postma EN, Biswal S, Fleuren L, Boyle EJ, Bechek S, O’Connor K, Shenoy A, Jonnalagadda D, Kim J, Shafi MS, Patel AB, Rosenthal ES, Westover MB. Electronic Health Data Predict Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurocritical Care 2017, 28: 184-193. PMID: 28983801, PMCID: PMC5886829, DOI: 10.1007/s12028-017-0466-8.Peer-Reviewed Original ResearchConceptsAneurysmal subarachnoid hemorrhageGlasgow Outcome ScaleWhite blood cellsIntracranial pressureAPACHE IIElectronic health dataSubarachnoid hemorrhageBetter outcomesSingle-center retrospective cohort studyDischarge Glasgow Outcome ScaleEarly goal-directed therapyAPACHE II scoreGoal-directed therapyRetrospective cohort studyMean arterial pressureRisk stratification scoresAdmission APACHE IIPredictors of outcomeMultivariate analysis predictorsLogistic regression modelsHealth dataAdmission dayII scoreNeurologic outcomeArterial pressure
2016
Resuscitation of the Patient in Septic Shock
Kodadek L, Lipsett P. Resuscitation of the Patient in Septic Shock. 2016, 25-42. DOI: 10.1007/978-3-319-42376-0_3.ChaptersEarly goal-directed therapySurviving Sepsis CampaignSeptic shockHemodynamic goalsSepsis resuscitationUsual careLife-threatening organ dysfunctionSubset of sepsisGoal-directed therapyMainstay of managementEmergency department patientsResuscitation of patientsEvidence-based guidelinesLarge volume resuscitationNormalization of lactateQuantitative resuscitationSepsis CampaignBlood transfusionDepartment patientsOrgan dysfunctionMetabolic abnormalitiesVolume resuscitationEffective resuscitationIntravenous fluidsAntibiotic treatmentEarly goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE
Nguyen HB, Jaehne AK, Jayaprakash N, Semler MW, Hegab S, Yataco AC, Tatem G, Salem D, Moore S, Boka K, Gill JK, Gardner-Gray J, Pflaum J, Domecq JP, Hurst G, Belsky JB, Fowkes R, Elkin RB, Simpson SQ, Falk JL, Singer DJ, Rivers EP. Early goal-directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE. Critical Care 2016, 20: 160. PMID: 27364620, PMCID: PMC4929762, DOI: 10.1186/s13054-016-1288-3.Peer-Reviewed Original ResearchConceptsEarly goal-directed therapyGoal-directed therapySeptic shockSevere sepsisSepsis mortalitySepsis managementSignificant mortality reductionSurviving Sepsis CampaignAcute myocardial infarctionStandard of careEarly sepsis managementHemodynamic pathogenesisUsual careSepsis CampaignStandard careEmergency departmentMyocardial infarctionEarly managementOutcome benefitsClinical trialsMortality reductionTherapyMortalityTrialsCare
2013
Paediatric community-acquired septic shock: results from the REPEM network study
Van de Voorde P, Emerson B, Gomez B, Willems J, Yildizdas D, Iglowstein I, Kerkhof E, Mullen N, Pinto CR, Detaille T, Qureshi N, Naud J, De Dooy J, Van Lancker R, Dupont A, Boelsma N, Mor M, Walker D, Sabbe M, Hachimi-Idrissi S, Da Dalt L, Waisman H, Biarent D, Maconochie I, Moll H, Benito J. Paediatric community-acquired septic shock: results from the REPEM network study. European Journal Of Pediatrics 2013, 172: 667-674. PMID: 23354787, PMCID: PMC3631515, DOI: 10.1007/s00431-013-1930-x.Peer-Reviewed Original ResearchConceptsPediatric Overall Performance CategoryMechanical ventilationEmergency departmentEarly goal-directed therapyOverall Performance CategorySubsequent intensive careUse of dobutamineFuture prospective trialsGoal-directed therapyIntensive care admissionProspective observational trialLower base excessVasoactive medicationsCare admissionSevere sepsisSignificant comorbiditiesVasoactive supportProspective trialDisease courseOrgan dysfunctionOverall mortalitySeptic shockED consultationsObservational trialConcomitant treatment
2008
Abdominal compartment syndrome
Maerz L, Kaplan LJ. Abdominal compartment syndrome. Critical Care Medicine 2008, 36: s212-s215. PMID: 18382196, DOI: 10.1097/ccm.0b013e318168e333.Peer-Reviewed Original ResearchConceptsAbdominal compartment syndromeAcute renal failureAcute kidney injuryCompartment syndromeRenal failureKidney injuryEarly goal-directed therapySecondary abdominal compartment syndromeMedical disease managementGoal-directed therapyIntensive care unitInitial resuscitationSevere sepsisSeptic shockCare unitDiagnostic modalitiesMedical diseasesTherapeutic interventionsSyndromeDisease managementSecondary eventsInjuryFailureSepsisSurgery
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