2024
Dissociable effects of mild COVID-19 on short- and long-term memories
Atkinson L, Thom J, Nobre A, Zokaei N. Dissociable effects of mild COVID-19 on short- and long-term memories. Brain Communications 2024, 6: fcae270. PMID: 39210912, PMCID: PMC11358641, DOI: 10.1093/braincomms/fcae270.Peer-Reviewed Original ResearchLong-term memoryLong-term memory representationsShort-term memory performanceMemory performanceMemory representationsPrecision of memory representationsPresence of cognitive deficitsTests of memory performanceLong-term memory performanceHealthy controlsCore deficitAssess memoryCognitive deficitsDissociative effectsMemoryExamination performanceResponse demandsImpairmentMeasures of accuracyDeficitsTaskSpatial locationPerformance changesSensitive frameworkAbstract Recent studies
2016
Brain responses to biological motion predict treatment outcome in young children with autism
Yang D, Pelphrey KA, Sukhodolsky DG, Crowley MJ, Dayan E, Dvornek NC, Venkataraman A, Duncan J, Staib L, Ventola P. Brain responses to biological motion predict treatment outcome in young children with autism. Translational Psychiatry 2016, 6: e948-e948. PMID: 27845779, PMCID: PMC5314125, DOI: 10.1038/tp.2016.213.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderYoung childrenSocial information processingMultivariate pattern analysisMotivation/rewardBiological motionCore deficitComplex neurodevelopmental disorderBrain responsesResponse treatmentSpectrum disorderNeurobiological markersNeural predictorsInformation processingBehavioral interventionsIndividual childrenNeurodevelopmental disordersCurrent findingsNeural circuitsBehavioral deficitsEarly childhoodChildrenUnsuccessful interventionsNeurobiomarkersPattern analysis
2014
Computational Psychiatry
Wang XJ, Krystal JH. Computational Psychiatry. Neuron 2014, 84: 638-654. PMID: 25442941, PMCID: PMC4255477, DOI: 10.1016/j.neuron.2014.10.018.Peer-Reviewed Original ResearchMeasuring social communication behaviors as a treatment endpoint in individuals with autism spectrum disorder
Anagnostou E, Jones N, Huerta M, Halladay A, Wang P, Scahill L, Horrigan J, Kasari C, Lord C, Choi D, Sullivan K, Dawson G. Measuring social communication behaviors as a treatment endpoint in individuals with autism spectrum disorder. Autism 2014, 19: 622-636. PMID: 25096930, DOI: 10.1177/1362361314542955.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderSymptom domainsEarly indicator of autism spectrum disorderMeasures of social communicationSocial communicationIndicator of autism spectrum disorderSocial communication impairmentsSocial communication measuresSocial communication deficitsSocial communication behaviorsCore deficitCommunication deficitsCommunication impairmentsAutism SpeaksPsychometric propertiesOutcome measuresAutismCommunication measuresTreatment targetCommunication behaviorsTreatment approachesDisordersMonthly conference callsTreatment endpointGoing up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia.
Boggs DL, Carlson J, Cortes-Briones J, Krystal JH, D'Souza DC. Going up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia. Current Pharmaceutical Design 2014, 20: 5077-92. PMID: 24345265, PMCID: PMC4442779, DOI: 10.2174/1381612819666131216121019.Peer-Reviewed Original ResearchConceptsCognitive impairmentStandardized cognitive test batteryCognitive test batteryInformation processing impairmentsNicotinic medicationsProcessing impairmentsCore deficitAttentional deficitsTest batteryCognitive deficitsProximal measuresBrain functionCognitionSchizophreniaDeficitsImpairmentNumber of medicationsNicotinic acetylcholine receptorsCertain symptomsConsistent improvementClinical evidenceTreatment strategiesClinical studiesNicotinic receptorsClinical utility
2013
The role of imitation in the observed heterogeneity in EEG mu rhythm in autism and typical development
Bernier R, Aaronson B, McPartland J. The role of imitation in the observed heterogeneity in EEG mu rhythm in autism and typical development. Brain And Cognition 2013, 82: 69-75. PMID: 23511847, DOI: 10.1016/j.bandc.2013.02.008.Peer-Reviewed Original ResearchConceptsMirror neuron system functionAutism spectrum disorderEEG mu rhythmImitation abilityMNS activityMu rhythmExecution/observation matching systemGoal-directed hand actionsMirror neuron systemObservation of actionsRole of imitationImitative skillsMNS functionCore deficitAction observationTypical developmentUniversal impairmentASD symptomsASD sampleHand actionsSocial deficitsSpectrum disorderSubset of childrenNeuron systemNormative patterns
2011
Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder
Campbell D, Datta D, Jones S, Batey Lee E, Sutcliffe J, Hammock E, Levitt P. Association of oxytocin receptor (OXTR) gene variants with multiple phenotype domains of autism spectrum disorder. Journal Of Neurodevelopmental Disorders 2011, 3: 101-112. PMID: 21484202, PMCID: PMC3113442, DOI: 10.1007/s11689-010-9071-2.Peer-Reviewed Original ResearchAutism spectrum disorderASD susceptibilitySocial behaviorGenetic association analysisSpectrum disorderGenetic variationOxytocin receptor gene variantsGenetic polymorphismsGenetic markersAssociation analysisLines of evidenceCommon genetic polymorphismsPhenotype domainsCore deficitBehavioral flexibilityOXTR polymorphismsPolymorphismOXTR geneGene variantsASD phenotypeSubset of familiesASD riskCurrent findingsLarge independent cohortsFunctional polymorphisms
2009
Increasing Independence in Autism Spectrum Disorders: A Review of Three Focused Interventions
Hume K, Loftin R, Lantz J. Increasing Independence in Autism Spectrum Disorders: A Review of Three Focused Interventions. Journal Of Autism And Developmental Disorders 2009, 39: 1329-1338. PMID: 19430897, DOI: 10.1007/s10803-009-0751-2.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAttentionAutistic DisorderAwarenessBehavior TherapyCognition DisordersCuesGeneralization, PsychologicalHumansImitative BehaviorPractice, PsychologicalProgrammed Instructions as TopicReinforcement, PsychologySelf CareSocial BehaviorSocial EnvironmentTransfer, PsychologyVideo RecordingConceptsAutism spectrum disorderExecutive function deficitsSpectrum disorderFunction deficitsFeatures of autismIndividual work systemsCore deficitVideo modelingStimulus controlAlternative stimuliAdult supportRelationship developmentWork systemsFocused interventionsIndependent performanceEffective interventionsIndependent demonstrationIntervention strategiesDeficitsAdult managementPoor long-term outcomesAutismDisordersInterventionStimuli
2002
Impaired detection of visual motion in schizophrenia patients
Li CS. Impaired detection of visual motion in schizophrenia patients. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2002, 26: 929-934. PMID: 12369268, DOI: 10.1016/s0278-5846(02)00207-5.Peer-Reviewed Original ResearchConceptsSchizophrenia patientsNormal controlsNormal subjectsPatientsSignal detection theorySimilar deficitsImpaired detectionCore deficitAttention impairmentMotion stimuliSensory modalitiesVisual tasksResponse biasVisual motionRecent reportsAuditory detectionDetection theoryTrialsDeficitsRandom dotsPsychometric functionsSignal intensitySensitivity variesGroupCoherent direction
2000
Psychosocial Interventions Individual Psychotherapy with the Child, and Family Interventions
Stubbe D, Weiss G. Psychosocial Interventions Individual Psychotherapy with the Child, and Family Interventions. Child And Adolescent Psychiatric Clinics Of North America 2000, 9: 663-670. PMID: 10944661, DOI: 10.1016/s1056-4993(18)30111-1.Peer-Reviewed Original ResearchConceptsCore deficitFamily interventionsIndividual psychotherapyDifferential contributionADHDComplex neuropsychiatric disorderEfficacious treatmentNeuropsychiatric disordersFunctional impairmentMedication treatmentConcomitant functional impairmentEffective treatment modalityLong-term outcomesDisordersPsychotherapyDeficitsTreatment modalitiesImpairmentChildrenComplex disorderSubstantial gainsIntervention
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