2025
Co-occurring Psychopathology in Children With and Without Autism Spectrum Disorder (ASD): Differences by Sex in the ECHO Cohorts
Volk H, Fortes D, Musci R, Kim A, Bastain T, Camargo C, Croen L, Dabelea D, Duarte C, Dunlop A, Gachigi K, Ghassabian A, Hertz-Picciotto I, Huddleston K, Joseph R, Keating D, Kelly R, Kim Y, Landa R, Leve L, Lyall K, Northrup J, O’Connor T, Ozonoff S, Ross A, Schmidt R, Schweitzer J, Shuffrey L, Shuster C, Vance E, Weiss S, Wilkening G, Wright R. Co-occurring Psychopathology in Children With and Without Autism Spectrum Disorder (ASD): Differences by Sex in the ECHO Cohorts. Journal Of Autism And Developmental Disorders 2025, 1-12. PMID: 39762643, PMCID: PMC12409737, DOI: 10.1007/s10803-024-06670-2.Peer-Reviewed Original ResearchChild Behavior ChecklistAutism spectrum disorderAttention-deficit/hyperactivity disorderSocial Responsiveness ScaleEmotional problemsSpectrum disorderTotal problemsAutism diagnosisCo-occurring psychopathologyChild sexDiagnosis of autism spectrum disorderSocial Responsiveness Scale scoresDSM-oriented subscalesParent-reported depressionSocial communication deficitsChild Behavior Checklist TotalCBCL total problemsProblem scale scoresNon-autistic childrenHigher CBCL scoresNational sampleAttention-deficit/hyperactivityCommunication deficitsBehavior ChecklistChild health outcomes
2024
Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder Pathways
Binder M, Escobar I, Xu Y, Sokolov A, Zhang L, Bordey A. Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder Pathways. Journal Of Neuroscience 2024, 44: e1245232024. PMID: 39164108, PMCID: PMC11426378, DOI: 10.1523/jneurosci.1245-23.2024.Peer-Reviewed Original ResearchPup isolation callsFilamin AIsolation callsAutism spectrum disorderSigns of autism spectrum disorderPyramidal neuronsConstitutively active mutantCommunication deficitsDownstream of ERK1/2MTOR complex 1Actin crosslinkingSynaptic connectionsExpression of RhebSpine densityActive mutantActive RhebCore pathwaysRhebCortical synaptic connectivityCellular mosaicismConstitutively active RhebOne-month-old miceExcitatory synaptic activityNeocortex of miceSocial communicationLoss of Katnal2 leads to ependymal ciliary hyperfunction and autism-related phenotypes in mice
Kang R, Kim K, Jung Y, Choi S, Lee C, Im G, Shin M, Ryu K, Choi S, Yang E, Shin W, Lee S, Lee S, Papadopoulos Z, Ahn J, Koh G, Kipnis J, Kang H, Kim H, Cho W, Park S, Kim S, Kim E. Loss of Katnal2 leads to ependymal ciliary hyperfunction and autism-related phenotypes in mice. PLOS Biology 2024, 22: e3002596. PMID: 38718086, PMCID: PMC11104772, DOI: 10.1371/journal.pbio.3002596.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderBehavioral phenotypesASD-relatedSocial communication deficitsAutism-related phenotypesEnlarged lateral ventriclesProgressive ventricular enlargementCommunication deficitsSpectrum disorderSynaptic deficitsEnlargement of brain ventriclesTranscriptomic changesMicrotubule-regulatory proteinsGenes down-regulatedBrain ventriclesVentricular enlargementLateral ventricleDeficitsHippocampal neuronsMotile ciliaKATNAL2Potential treatmentDown-regulationCiliary functionEpendymal cells
2021
Predictors of social functioning and quality of life in schizophrenia and autism spectrum disorder
Corbera S, Wexler BE, Bell MD, Pearlson G, Mayer S, Pittman B, Belamkar V, Assaf M. Predictors of social functioning and quality of life in schizophrenia and autism spectrum disorder. Psychiatry Research 2021, 303: 114087. PMID: 34246005, PMCID: PMC8373814, DOI: 10.1016/j.psychres.2021.114087.Peer-Reviewed Original ResearchConceptsSocial functioningCognitive empathyNegative symptomsAutism spectrum disorderWorse social functioningGreater negative symptomsHigher social functioningAffective empathySocial cognitionPersonal distressCommunication deficitsSpectrum disorderFunctioning impairmentQuality of lifeEmpathy scoresASDHigher QoLIQHealthy controlsEmpathySymptom severityDeficitsSchizophreniaWorse QOLFunctioningTraumatic Brain Injury
Lê K, Mozeiko J. Traumatic Brain Injury. 2021, 590-612. DOI: 10.1002/9781119606987.ch25.Peer-Reviewed Original ResearchCognitive-communication disordersTraumatic brain injuryMonologic discourseManagement of cognitive-communication disordersConversational discourseAnalysis of conversational discourseBrain injuryAreas of attentionSuper structural levelPragmatic deficitsExecutive functionCommunication deficitsLanguage functionNonverbal behaviorLinguistic unitsCognitive interpretationResponse appropriatenessCommunication abilityDiscourseInformation processingTopical managementDeficitsSocial reintegrationDisordersPervasive nature
2015
Interactive social neuroscience to study autism spectrum disorder.
Rolison MJ, Naples AJ, McPartland JC. Interactive social neuroscience to study autism spectrum disorder. The Yale Journal Of Biology And Medicine 2015, 88: 17-24. PMID: 25745371, PMCID: PMC4345534.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAutism spectrum disorderSocial neuroscienceSpectrum disorderNeuropathology of ASDNeuroscience approachNeuroscience methodsNeural processesSocial difficultiesNeural mechanismsCommunication deficitsASD researchContext of interactionNeuroscience researchSocial interactionBrain regionsNeuroscienceDifficultiesLimited insightDisordersContextBrainDeficitsResearchIndividualsPeople
2014
Measuring social communication behaviors as a treatment endpoint in individuals with autism spectrum disorder
Anagnostou E, Jones N, Huerta M, Halladay A, Wang P, Scahill L, Horrigan J, Kasari C, Lord C, Choi D, Sullivan K, Dawson G. Measuring social communication behaviors as a treatment endpoint in individuals with autism spectrum disorder. Autism 2014, 19: 622-636. PMID: 25096930, DOI: 10.1177/1362361314542955.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderSymptom domainsEarly indicator of autism spectrum disorderMeasures of social communicationSocial communicationIndicator of autism spectrum disorderSocial communication impairmentsSocial communication measuresSocial communication deficitsSocial communication behaviorsCore deficitCommunication deficitsCommunication impairmentsAutism SpeaksPsychometric propertiesOutcome measuresAutismCommunication measuresTreatment targetCommunication behaviorsTreatment approachesDisordersMonthly conference callsTreatment endpoint
2013
Characterizing Discourse Deficits Following Penetrating Head Injury: A Preliminary Model
Coelho C, Lê K, Mozeiko J, Hamilton M, Tyler E, Krueger F, Grafman J. Characterizing Discourse Deficits Following Penetrating Head Injury: A Preliminary Model. American Journal Of Speech-Language Pathology 2013, 22: s438-s448. PMID: 23695915, PMCID: PMC7684633, DOI: 10.1044/1058-0360(2013/12-0076).Peer-Reviewed Original ResearchConceptsNon-brain-injuredClosed head injuryDiscourse productionDiscourse performanceNon-brain-injured groupAdequate-to-good fitMeasures of memoryPenetrating Head InjuryStructural equation modeling proceduresGroups of participantsTraumatic brain injuryDiscourse deficitsDiscourse measuresExecutive functionNarrative lengthCommunication deficitsMacrostructural componentsHead injuryStory grammarBrain-injuredStory narrativesBrain injuryGroup of individualsDeficitsDiscourse data
2010
Traumatic Brain Injury
Mozeiko J, Lé K, Coelho C. Traumatic Brain Injury. 2010, 577-599. DOI: 10.1002/9781444318975.ch25.Peer-Reviewed Original Research
2001
Assessment of Children With Pervasive Developmental Disorders
Koenig K, Scahill L. Assessment of Children With Pervasive Developmental Disorders. Journal Of Child And Adolescent Psychiatric Nursing 2001, 14: 159-166. PMID: 11767506, DOI: 10.1111/j.1744-6171.2001.tb00309.x.Peer-Reviewed Original ResearchConceptsAdvanced practice nursesPervasive developmental disorderDevelopmental disordersChildhood psychiatric disordersGroup of conditionsPractice nursesAssessment of childrenAppropriate diagnosisPsychiatric disordersClinical experienceCounseling parentsDisordersFurther consultationInterventionCurrent literatureDiagnosisCommunication deficitsDiagnostic instrumentRepetitive behaviorsChildrenNormal growthFormal trainingNursesParents
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