2024
Association of door-to-balloon time and one-year outcomes in hospital survivors of ST-elevation myocardial infarction
Sawano M, Kohsaka S, Murugiah K, Ishii H, Yamaji K, Takahashi J, Ozaki K, Amano T, Kozuma K. Association of door-to-balloon time and one-year outcomes in hospital survivors of ST-elevation myocardial infarction. Journal Of Cardiology 2024, 85: 98-99. PMID: 38964710, DOI: 10.1016/j.jjcc.2024.06.009.Peer-Reviewed Original ResearchDoor-to-balloon timeST-elevation myocardial infarctionAdjusted hazard ratiosSurvivors of ST-elevation myocardial infarctionMyocardial infarctionPatients aged <Specific patient subgroupsAdverse cardiovascular eventsOne-year outcomesAcute coronary eventsRevascularization historyMACE riskCardiogenic shockCoronary revascularizationOutcomes RegistryCardiovascular eventsHospital survivorsPatient subgroupsCardiac arrestSubgroup analysisCardiovascular outcomesHazard ratioHigher comorbiditiesCoronary eventsPrimary prevention
2021
Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Ward-Caviness C, Diaz-Sanchez D, Kraus W, Hauser E, Schwartz J, Peters A, Schneider A. Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort. Environmental Pollution 2021, 275: 116663. PMID: 33581627, DOI: 10.1016/j.envpol.2021.116663.Peer-Reviewed Original ResearchConceptsFine particulate matterParticulate matterDaily PM<sub>2.5</sub> concentrationsShort-term exposure to ambient fine particulate matterAcute PM<sub>2.5</sub> exposureAssociation of PM<sub>2.5</sub> wiElevated PM<sub>2.5</sub>Exposure to ambient fine particulate matterExposure to fine particulate matterAmbient fine particulate matterParticipant's residential addressCTnT testNeural network-based hybrid modelResidential addressesElevated indicatorsMeasurement of NT-pro-BNPConcentrationMatterMyocardial infarction symptomsDuke University HospitalInfarction symptomsRural areasOdds ratioCoronary eventsInterquartile range
2020
Chronic Stress and Risks for Myocardial Infarction in U.S. Adults
Farmer H, Xu H, Navar A, Nanna M, George L, Dupre M. Chronic Stress and Risks for Myocardial Infarction in U.S. Adults. Innovation In Aging 2020, 4: 394-395. PMCID: PMC7742362, DOI: 10.1093/geroni/igaa057.1270.Peer-Reviewed Original ResearchMyocardial infarctionRisk factorsChronic stressChronic stressorsHistory of MIU.S. adultsRepresentative prospective cohort studyRecurrent myocardial infarctionAcute coronary eventsClinical risk factorsProspective cohort studyPrior myocardial infarctionSignificant risk factorsAcute myocardial infarctionProportional hazards modelCoronary eventsCohort studyMI incidenceCardiovascular healthHazards modelLong-term exposureAdultsInfarctionRiskPersonal healthCOVID‐19 complicated by ST‐segment elevation myocardial infarction in a 29‐year‐old patient
Ong E, Castro‐Dominguez Y, Brennan J, Oen‐Hsiao J. COVID‐19 complicated by ST‐segment elevation myocardial infarction in a 29‐year‐old patient. Catheterization And Cardiovascular Interventions 2020, 97: 267-271. PMID: 32672402, PMCID: PMC7405222, DOI: 10.1002/ccd.29102.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionMyocardial infarctionAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionCoronavirus 2 infectionAcute coronary eventsCoronary eventsInflammatory markersCardiac catheterizationHypercoagulable stateTotal occlusionMedical historyCoronavirus diseaseCOVID-19InfarctionLaboratory testingCatheterizationPatientsArteryThrombusInfectionDiseaseOcclusion
2014
Relation of C-Reactive Protein Levels to Instability of Untreated Vulnerable Coronary Plaques (from the PROSPECT Study)
Kelly CR, Weisz G, Maehara A, Mintz GS, Mehran R, Lansky AJ, Parise H, de Bruyne B, Serruys PW, Stone GW. Relation of C-Reactive Protein Levels to Instability of Untreated Vulnerable Coronary Plaques (from the PROSPECT Study). The American Journal Of Cardiology 2014, 114: 376-383. PMID: 24931291, DOI: 10.1016/j.amjcard.2014.04.048.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersC-Reactive ProteinCoronary AngiographyCoronary Artery DiseaseDisease ProgressionFemaleGlobal HealthHumansIncidenceInflammationMaleMiddle AgedPlaque, AtheroscleroticPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexSurvival RateTime FactorsConceptsMajor adverse cardiac eventsC-reactive protein levelsNonculprit lesionsElevated CRP levelsCRP levelsVulnerable coronary plaquesIntravascular ultrasoundCoronary plaquesPost-acute coronary syndrome patientsSubsequent major adverse cardiac eventsGray-scale intravascular ultrasoundCoronary Tree (PROSPECT) studyUntreated nonculprit lesionsAdverse cardiac eventsAdverse coronary eventsAcute coronary syndromeCoronary syndrome patientsPercutaneous coronary interventionRadiofrequency intravascular ultrasoundPredictors of eventsProtein levelsMinimal luminal areaHigh rateCoronary eventsCoronary syndrome
2013
Systolic Blood Pressure and Cardiovascular Outcomes During Treatment of Hypertension
Weber MA, Bakris GL, Hester A, Weir MR, Hua TA, Zappe D, Dahlof B, Velazquez EJ, Pitt B, Jamerson K. Systolic Blood Pressure and Cardiovascular Outcomes During Treatment of Hypertension. The American Journal Of Medicine 2013, 126: 501-508. PMID: 23541376, DOI: 10.1016/j.amjmed.2013.01.007.Peer-Reviewed Original ResearchConceptsSystolic blood pressureHigh-risk hypertensive patientsPrimary end pointBlood pressure levelsSystolic bloodBlood pressureCardiovascular deathCardiovascular eventsCardiovascular outcomesCoronary eventsEnd pointHypertensive patientsMyocardial infarctionSystolic blood pressure levelsAvoiding Cardiovascular EventsSystolic Hypertension (ACCOMPLISH) trialTotal myocardial infarctionBlood pressure groupMajor cardiovascular eventsMean patient ageNonfatal myocardial infarctionCardiovascular event ratesRenal end pointsLower blood pressureTreatment of hypertension
2012
Longitudinal Distribution of Plaque Burden and Necrotic Core–Rich Plaques in Nonculprit Lesions of Patients Presenting With Acute Coronary Syndromes
Wykrzykowska JJ, Mintz GS, Garcia-Garcia HM, Maehara A, Fahy M, Xu K, Inguez A, Fajadet J, Lansky A, Templin B, Zhang Z, de Bruyne B, Weisz G, Serruys PW, Stone GW. Longitudinal Distribution of Plaque Burden and Necrotic Core–Rich Plaques in Nonculprit Lesions of Patients Presenting With Acute Coronary Syndromes. JACC Cardiovascular Imaging 2012, 5: s10-s18. PMID: 22421223, DOI: 10.1016/j.jcmg.2012.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryChi-Square DistributionCoronary Artery DiseaseCoronary StenosisCoronary VesselsEuropeFemaleHumansLipidsMaleMiddle AgedMyocardial InfarctionNecrosisPhenotypePlaque, AtheroscleroticPredictive Value of TestsProspective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesConceptsLeft main coronary arteryVirtual histology intravascular ultrasoundAcute coronary syndromePlaque burdenDistal coronary treeNonculprit lesionsCoronary syndromeVH-TCFACoronary arteryCoronary treeNecrotic core contentAcute coronary eventsEpicardial coronary arteriesMain coronary arteryAtherosclerotic plaque burdenAcute myocardial infarctionLong segmentCoronary eventsAnterior descendingMyocardial infarctionVulnerable plaquesProportion of NCsArteryLesionsPROSPECT study
2007
Effects of Torcetrapib in Patients at High Risk for Coronary Events
Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, Lopez-Sendon J, Mosca L, Tardif JC, Waters DD, Shear CL, Revkin JH, Buhr KA, Fisher MR, Tall AR, Brewer B. Effects of Torcetrapib in Patients at High Risk for Coronary Events. New England Journal Of Medicine 2007, 357: 2109-2122. PMID: 17984165, DOI: 10.1056/nejmoa0706628.Peer-Reviewed Original ResearchConceptsMajor cardiovascular eventsRisk of deathCardiovascular eventsCholesteryl ester transfer proteinLipoprotein cholesterolFirst major cardiovascular eventHigh-density lipoprotein cholesterolLow-density lipoprotein cholesterolEffects of torcetrapibHigh cardiovascular riskNonfatal myocardial infarctionDouble-blind studySystolic blood pressureCoronary heart diseaseRisk of mortalityPlasma lipoprotein levelsEster transfer proteinCoronary eventsCardiac eventsCardiovascular riskUnstable anginaBlood pressurePrimary outcomeSerum potassiumLipoprotein levelsRegulation of ion channels and arrhythmias in the ischemic heart
Akar JG, Akar FG. Regulation of ion channels and arrhythmias in the ischemic heart. Journal Of Electrocardiology 2007, 40: s37-s41. PMID: 17993326, DOI: 10.1016/j.jelectrocard.2007.05.020.Peer-Reviewed Original ResearchConceptsIschemic injuryElectrophysiological changesIschemic heart diseaseBest treatment strategyCoronary eventsReperfusion phaseVentricular arrhythmiasIschemic episodesHeart diseaseLeading causeElectrical dysfunctionTreatment strategiesIschemic heartMetabolic substratesPatientsArrhythmiasKey cellularTime courseInjuryIon channelsHeartDysfunctionMortalityDisease
2005
Aspirin Use in Older Patients With Heart Failure and Coronary Artery Disease National Prescription Patterns and Relationship With Outcomes
Masoudi FA, Wolfe P, Havranek EP, Rathore SS, Foody JM, Krumholz HM. Aspirin Use in Older Patients With Heart Failure and Coronary Artery Disease National Prescription Patterns and Relationship With Outcomes. Journal Of The American College Of Cardiology 2005, 46: 955-962. PMID: 16168275, DOI: 10.1016/j.jacc.2004.07.062.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseHeart failureAspirin prescriptionAspirin useRenal insufficiencyLower riskLower unadjusted ratesNational prescription patternsUse of aspirinClustering of patientsEvidence of harmCause readmissionCoronary eventsOlder patientsPrescription patternsSecondary preventionArtery diseaseACE inhibitorsMultivariable analysisUnadjusted ratesHospital characteristicsTreatment benefitMedicare beneficiariesAspirinPatients
2004
Dietary Fiber and Risk of Coronary Heart Disease: A Pooled Analysis of Cohort Studies
Pereira MA, O'Reilly E, Augustsson K, Fraser GE, Goldbourt U, Heitmann BL, Hallmans G, Knekt P, Liu S, Pietinen P, Spiegelman D, Stevens J, Virtamo J, Willett WC, Ascherio A. Dietary Fiber and Risk of Coronary Heart Disease: A Pooled Analysis of Cohort Studies. JAMA Internal Medicine 2004, 164: 370-376. PMID: 14980987, DOI: 10.1001/archinte.164.4.370.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseDietary fiber intakeHeart diseaseFiber intakeCoronary deathCoronary eventsCohort studyPooled analysisD incrementDietary fiberVegetable fiber intakeProspective cohort studyBody mass indexSex-specific resultsMass indexLifestyle factorsCoronary casesEpidemiologic studiesDiseaseIntakeDeathRiskWomenTotal dietary fiberMen
2002
Device selection in the treatment of in-stent restenosis with and without radiation (from the Gamma Radiation Trials)
Ajani AE, Waksman R, Zimarino M, Kim H, Pichard AD, Satler LF, Kent KM, White RL, Pinnow E, Mehran R, Lansky A, Lindsay J. Device selection in the treatment of in-stent restenosis with and without radiation (from the Gamma Radiation Trials). The American Journal Of Cardiology 2002, 89: 137-144. PMID: 11792331, DOI: 10.1016/s0002-9149(01)02189-0.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnalysis of VarianceAngioplastyAngioplasty, Balloon, CoronaryChi-Square DistributionCoronary DiseaseDose-Response Relationship, RadiationFemaleHumansIridium RadioisotopesLogistic ModelsMaleMiddle AgedProspective StudiesRisk FactorsSecondary PreventionStentsTreatment OutcomeVascular PatencyConceptsExcimer laser coronary angioplastyMajor adverse coronary eventsAdditional stent implantationTreatment of ISRRecurrence rateCoronary angioplastyRotational atherectomyStent implantationStent restenosisBalloon percutaneous transluminal coronary angioplastyPercutaneous transluminal coronary angioplastyIntracoronary gamma radiationLate clinical outcomesAdverse coronary eventsOverall recurrence rateTransluminal coronary angioplastyLaser coronary angioplastyHigh recurrence rateUse of stentingDevice selectionAngiographic characteristicsMACE ratePlacebo groupPlacebo therapyCoronary events
1999
One-year follow-up after intravascular ultrasound assessment of moderate left main coronary artery disease in patients with ambiguous angiograms
Abizaid A, Mintz G, Abizaid A, Mehran R, Lansky A, Pichard A, Satler L, Wu H, Kent K, Leon M. One-year follow-up after intravascular ultrasound assessment of moderate left main coronary artery disease in patients with ambiguous angiograms. Journal Of The American College Of Cardiology 1999, 34: 707-715. PMID: 10483951, DOI: 10.1016/s0735-1097(99)00261-2.Peer-Reviewed Original ResearchConceptsMinimum lumen diameterMain coronary artery diseaseCoronary artery diseaseLMCA diseaseCardiac eventsArtery diseaseLeft main coronary artery diseaseLumen diameterOne-year event ratesPoor long-term prognosisEvent ratesLesion lumen areaSignificant LMCA diseaseUnderwent bypass surgeryPresence of diabetesIntravascular ultrasound findingsLong-term prognosisCatheter-based interventionsIntravascular ultrasound assessmentLogistic regression analysisImportant quantitative predictorLMCA interventionCoronary eventsLMCA stenosisBypass surgeryAntibiotics for Myocardial Infarction?
Schussheim A, Fuster V. Antibiotics for Myocardial Infarction? Drugs 1999, 57: 283-291. PMID: 10193683, DOI: 10.2165/00003495-199957030-00002.Peer-Reviewed Original ResearchConceptsInfectious organismsAtherosclerotic lesionsFuture large-scale clinical trialsLarge-scale clinical trialsRecent pilot trialRecurrent coronary eventsCoronary artery diseaseElaboration of cytokinesEvidence of infectionVascular smooth muscle cellsCoronary artery plaquesRisk of restenosisSmooth muscle cellsDirect local effectsActive atherosclerosisCoronary eventsCoronary interventionInflammatory mechanismsArtery diseaseHypercoagulable statePathological examinationAtherosclerotic processSeroepidemiological investigationCoronary endotheliumArtery plaques
1998
Lipid-Lowering Therapy After Coronary Revascularization: The Interventional Cardiologist’s Perspective 11This work was supported by the Cardiology Research Foundation, Washington, DC.
Lansky A, Popma J, Mintz G, Laird J, Saucedo J, Leon M. Lipid-Lowering Therapy After Coronary Revascularization: The Interventional Cardiologist’s Perspective 11This work was supported by the Cardiology Research Foundation, Washington, DC. The American Journal Of Cardiology 1998, 81: 55e-62e. PMID: 9551596, DOI: 10.1016/s0002-9149(98)00199-4.Peer-Reviewed Original ResearchConceptsCoronary eventsCoronary interventionCholesterol levelsAggressive lipid-lowering therapyCardiology Research FoundationLipid-Lowering TherapyTreatment of stenosisPatients' cholesterol levelsLipid-laden plaqueCoronary revascularizationCoronary atherosclerosisUnderlying diseaseRevascularization proceduresAtherosclerotic progressionCardiologist's practiceAdvanced lesionsCholesterol reductionPlaque accumulationIntravascular ultrasoundOwn carePatientsTherapyInterventionRevascularizationAtherectomy
1997
Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor.
Mach F, Schönbeck U, Bonnefoy J, Pober J, Libby P. Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. Circulation 1997, 96: 396-9. PMID: 9244201, DOI: 10.1161/01.cir.96.2.396.Peer-Reviewed Original ResearchConceptsLigation of CD40Tissue factorMacrophage functionMonocyte/macrophage functionAcute coronary eventsAcute coronary syndromeAnti-CD40L antibodyHuman monocytes/macrophagesCytokine interleukin-1Mononuclear phagocyte functionMonocytes/macrophagesInduction of collagenaseActivated T cellsCoronary eventsCoronary syndromeMatrix-degrading proteinasesClinical manifestationsPlaque disruptionTumor necrosisT cell membranePlaque ruptureT cellsInterleukin-1Phagocyte functionReceptor CD40When to start cholesterol-lowering therapy in patients with coronary heart disease. A statement for healthcare professionals from the American Heart Association Task Force on Risk Reduction.
Grundy S, Balady G, Criqui M, Fletcher G, Greenland P, Hiratzka L, Houston-Miller N, Kris-Etherton P, Krumholz H, LaRosa J, Ockene I, Pearson T, Reed J, Smith S, Washington R. When to start cholesterol-lowering therapy in patients with coronary heart disease. A statement for healthcare professionals from the American Heart Association Task Force on Risk Reduction. Circulation 1997, 95: 1683-5. PMID: 9118557, DOI: 10.1161/01.cir.95.6.1683.Peer-Reviewed Original ResearchConceptsCholesterol-lowering therapyAggressive cholesterol-lowering therapyAtherosclerotic diseaseCholesterol loweringAmerican Heart Association Task ForceCholesterol-lowering trialsClinical atherosclerotic diseaseFuture coronary eventsHigh-risk patientsSubstantial clinical benefitMajority of patientsCoronary heart diseaseLDL cholesterol loweringPrimary care physiciansBenefits of therapyRisk-reducing treatmentsNonpharmaceutical approachesRecurrent CHDCoronary eventsCare physiciansClinical benefitCholesterol managementClinical managementHeart diseaseCholesterol reduction
1996
Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States
Ascherio A, Rimm E, Giovannucci E, Spiegelman D, Meir S, Willett W. Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. The BMJ 1996, 313: 84. PMID: 8688759, PMCID: PMC2351515, DOI: 10.1136/bmj.313.7049.84.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseHeart diseaseMyocardial infarctionFat intakeRisk factorsHealth professionalsFatal coronary heart diseaseNon-dietary risk factorsNon-fatal myocardial infarctionCohort questionnaire studyCoronary risk factorsMultivariate relative riskTotal fat intakeIntake of cholesterolAcute myocardial infarctionDiagnosed cardiovascular diseaseLinolenic acid intakeBlood cholesterol concentrationsIntake of fiberPositive associationCoronary deathCoronary eventsSpecific preventive effectCholesterol intakeCoronary diseaseDetection and significance of myocardial ischemia in women versus men within six months of acute myocardial infarction or unstable angina
Moriel M, Benhorin J, Brown M, Raubertas R, Severski P, Van Voorhees L, Bodenheimer M, Tzivoni D, Wackers F, Moss A, Group T. Detection and significance of myocardial ischemia in women versus men within six months of acute myocardial infarction or unstable angina. The American Journal Of Cardiology 1996, 77: 798-804. PMID: 8623730, DOI: 10.1016/s0002-9149(97)89172-2.Peer-Reviewed Original ResearchConceptsAcute coronary eventsThallium-201 stress scintigraphyPrimary end pointCoronary eventsEnd pointUnstable anginaStress scintigraphyPatient 1Myocardial infarctionNoninvasive testsExercise electrocardiogramAmbulatory electrocardiogramIschemia detectionCardiac event rateNonfatal myocardial infarctionSubsequent cardiac eventsAcute myocardial infarctionCardiac eventsIschemia testCardiac deathCox analysisPrognostic significanceMyocardial ischemiaEvent ratesWomen
1995
Body Size and Fat Distribution as Predictors of Coronary Heart Disease among Middle-aged and Older US Men
Rimm E, Stampfer M, Giovannucci E, Ascherio A, Spiegelman D, Colditz G, Willett W. Body Size and Fat Distribution as Predictors of Coronary Heart Disease among Middle-aged and Older US Men. American Journal Of Epidemiology 1995, 141: 1117-1127. PMID: 7771450, DOI: 10.1093/oxfordjournals.aje.a117385.Peer-Reviewed Original ResearchConceptsBody mass indexCoronary heart diseaseHeart diseaseFat distributionMass indexHip ratioProspective studyRisk factorsUS menAge-related hormonal changesIncident coronary heart diseaseLong-term prospective studiesCoronary risk factorsIncident coronary eventsStrong risk factorOlder US menRelative risk estimatesYears of ageCoronary eventsLean menCoronary diseaseObese menIndependent predictorsLong followRelative risk
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