2024
Selective mural cell recruitment of pericytes to networks of assembling endothelial cell-lined tubes
Yrigoin K, Davis G. Selective mural cell recruitment of pericytes to networks of assembling endothelial cell-lined tubes. Frontiers In Cell And Developmental Biology 2024, 12: 1389607. PMID: 38961866, PMCID: PMC11219904, DOI: 10.3389/fcell.2024.1389607.Peer-Reviewed Original ResearchCoronary artery smooth muscle cellsVascular basement membrane matrix depositionVascular basement membrane matrix assemblyEC tubesBasement membrane depositionVascular smooth muscle cellsSmooth muscle cellsInvestigate functional differencesMuscle cellsMatrix assemblyArtery smooth muscle cellsMural cell recruitmentPDGF-DDPlatelet-derived growth factor (PDGF)-BBCollagen matrixMembrane depositionMural cellsHuman coronary artery smooth muscle cellsMinimal recruitmentFunctional differencesEC-derived factorsEndothelin-1CellsMatrix environmentMinimal invasiveness
2020
Circular RNA CircMAP3K5 Acts as a MicroRNA-22-3p Sponge to Promote Resolution of Intimal Hyperplasia Via TET2-Mediated Smooth Muscle Cell Differentiation
Zeng Z, Xia L, Fan S, Zheng J, Qin J, Fan X, Liu Y, Tao J, Liu Y, Li K, Ling Z, Bu Y, Martin KA, Hwa J, Liu R, Tang WH. Circular RNA CircMAP3K5 Acts as a MicroRNA-22-3p Sponge to Promote Resolution of Intimal Hyperplasia Via TET2-Mediated Smooth Muscle Cell Differentiation. Circulation 2020, 143: 354-371. PMID: 33207953, DOI: 10.1161/circulationaha.120.049715.Peer-Reviewed Original ResearchConceptsHuman coronary artery smooth muscle cellsTet2 knockout miceCoronary artery smooth muscle cellsArtery smooth muscle cellsCircular RNAsSmooth muscle cellsVascular smooth muscle cellsWire-injured mouse femoral arteriesSmooth muscle cell differentiationCircular RNA profilingMuscle cell differentiationRNA sequencing dataLoss of TET2Coronary heart diseaseVascular SMC differentiationMiR-22-3pPlatelet-derived growth factorKnockout miceSMC differentiationMaster regulatorRNA sequencingRNA profilingPlatelet-derived growth factor-BBGene expressionSequencing data
2010
Goniothalamin induces mitochondria-mediated apoptosis via p53-dependent caspase-2 activation pathway in coronary artery smooth muscle cells
Chan K, Rajab N, Ross D, Inayat-Hussain S. Goniothalamin induces mitochondria-mediated apoptosis via p53-dependent caspase-2 activation pathway in coronary artery smooth muscle cells. Toxicology Letters 2010, 196: s260. DOI: 10.1016/j.toxlet.2010.03.867.Peer-Reviewed Original ResearchArtery smooth muscle cellsCoronary artery smooth muscle cellsSmooth muscle cellsMuscle cellsActivation pathwayGoniothalamin Induces Coronary Artery Smooth Muscle Cells Apoptosis: The p53-Dependent Caspase-2 Activation Pathway
Chan K, Rajab N, Siegel D, Bin Din L, Ross D, Inayat-Hussain S. Goniothalamin Induces Coronary Artery Smooth Muscle Cells Apoptosis: The p53-Dependent Caspase-2 Activation Pathway. Toxicological Sciences 2010, 116: 533-548. PMID: 20498002, DOI: 10.1093/toxsci/kfq151.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAmino Acid Chloromethyl KetonesApoptosisCaspase 2Cells, CulturedCytochromes cDose-Response Relationship, DrugEnzyme ActivationHumansHydrogen PeroxideMembrane Potential, MitochondrialMuscle, Smooth, VascularMyocytes, Smooth MuscleNAD(P)H Dehydrogenase (Quinone)Oxygen ConsumptionPyronesSuperoxidesTumor Suppressor Protein p53ConceptsCoronary artery smooth muscle cellsCaspase-2Pan-caspase inhibitor benzyloxycarbonylMitochondrial membrane potential lossAsp-fluoromethyl ketoneRole of mitochondriaExternalization of phosphatidylserineMembrane potential lossCaspase-3 cleavageMitochondrial releaseCaspase-8Molecular mechanismsUpstream signalsArtery smooth muscle cellsDNA damage
2001
Estradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect
Seli E, Selam B, Mor G, Kayisli U, Pehlivan T, Arici A. Estradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect. Menopause The Journal Of The North American Menopause Society 2001, 8: 296-301. PMID: 11449089, DOI: 10.1097/00042192-200107000-00013.Peer-Reviewed Original ResearchConceptsHuman coronary artery smooth muscle cellsCoronary artery smooth muscle cellsArtery smooth muscle cellsMonocyte chemotactic protein-1Smooth muscle cellsChemotactic protein-1Recruitment of macrophagesMCP-1 expressionMCP-1 proteinMuscle cellsProtective effectProtein 1Arterial wallSelective estrogen receptor modulatorsCoronary smooth muscle cellsMCP-1 protein productionEstrogen's protective effectPhenol red-free mediumCharcoal-stripped calf serumProtein productionEstrogen receptor modulatorsPathogenesis of atherosclerosisReverse transcriptase-polymerase chain reactionNorthern blotLow-density lipoprotein
1990
Mechanosensitive adenylate cyclase activity in coronary vascular smooth muscle cells
Mills I, Letsou G, Rabban J, Sumpio B, Gewirtz H. Mechanosensitive adenylate cyclase activity in coronary vascular smooth muscle cells. Biochemical And Biophysical Research Communications 1990, 171: 143-147. PMID: 2393388, DOI: 10.1016/0006-291x(90)91368-3.Peer-Reviewed Original ResearchConceptsVascular smooth muscle cellsSmooth muscle cellsCoronary vascular smooth muscle cellsMuscle cellsCyclase activityPorcine coronary artery smooth muscle cellsCultured vascular smooth muscle cellsArtery smooth muscle cellsCoronary artery smooth muscle cellsVascular smooth muscleMagnitude of stretchStretch-induced reductionAdenylate cyclase activityPotential biochemical mechanismsPerfusion pressureCoronary circulationCycles/minMyogenic responseSmooth muscleMechanical stretchAdenylate cyclasePotential mechanismsEntire time courseUnstretched cellsTime course
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