2023
The Combination Therapy of Glucocorticoids, Tacrolimus, and Mycophenolate Mofetil in Primary Membranous Nephropathy Coexisting with Type 2 Diabetes Mellitus: A Retrospective Study
Wang Y, Cui C, Tian X, Wang L, Ma X, Ge H, Zhang L, Xue X, Chen Z, Huo Y, Wang H, Fu R, Jia L. The Combination Therapy of Glucocorticoids, Tacrolimus, and Mycophenolate Mofetil in Primary Membranous Nephropathy Coexisting with Type 2 Diabetes Mellitus: A Retrospective Study. Integrative Medicine In Nephrology And Andrology 2023, 10: e00010. DOI: 10.1097/imna-d-22-00010.Peer-Reviewed Original ResearchPrimary membranous nephropathyMycophenolate mofetilCTX groupMembranous nephropathyType 2 diabetes mellitusCombination of glucocorticoidsSerum albumin levelUrinary protein excretionData of patientsLong-term efficacyWorse glycemic controlCTX regimenProteinuria reductionCyclophosphamide regimenAlbumin levelsDiabetes mellitusGlycemic controlImmunosuppressive agentsProtein excretionRetrospective studyCombination therapyBlood glucoseType 2Disease severityGlucocorticoids
2010
Effects of Cyclosporin A Therapy Combined with Steroids and Angiotensin Converting Enzyme Inhibitors on Childhood IgA Nephropathy
Shin J, Lim B, Kim P, Lee J, Jeong H, Kim J. Effects of Cyclosporin A Therapy Combined with Steroids and Angiotensin Converting Enzyme Inhibitors on Childhood IgA Nephropathy. Journal Of Korean Medical Science 2010, 25: 723-727. PMID: 20436708, PMCID: PMC2858831, DOI: 10.3346/jkms.2010.25.5.723.Peer-Reviewed Original ResearchConceptsCyA therapyIgA nephropathyDuration of CyA therapyTreated with CyADose of CyAAngiotensin-converting enzyme inhibitorsEffect of cyclosporin AFollow-up biopsiesUrinary protein excretionCyA-induced nephrotoxicityChildhood IgA nephropathyConverting Enzyme InhibitorsCyA levelsCreatinine clearanceHistological gradeSerum creatinineReduce proteinuriaProtein excretionClinical outcomesDrug levelsRenal pathologyCyclosporin ABlood pressureTherapyCyA
2009
Aliskiren and the Kidney: Beyond Hypertension
Trimarchi H, Orías M. Aliskiren and the Kidney: Beyond Hypertension. Nephrology Research & Reviews 2009, 1: 1-4. DOI: 10.4081/nr.2009.e1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPlasma renin activityRenin activityReceptor blockersGlomerular diseaseRenin angiotensin aldosterone systemAldosterone receptor blockersEndstage kidney diseaseAngiotensin aldosterone systemAngiotensin receptor blockersRenal disease progressionSecondary glomerular diseasesUse of angiotensinRenin-angiotensin systemUrinary protein excretionNew therapeutic optionsDiabetic nephropathyProtein excretionKidney diseaseTherapeutic optionsDisease progressionComplete blockadeUrinary proteinSide effectsEnzyme inhibitorsImportant cause
2002
Reversible acute renal failure and nephrotic syndrome in a Type 1 diabetic patient
Avilés-Santa L, Alpern R, Raskin P. Reversible acute renal failure and nephrotic syndrome in a Type 1 diabetic patient. Journal Of Diabetes And Its Complications 2002, 16: 249-254. PMID: 12015196, DOI: 10.1016/s1056-8727(01)00221-5.Peer-Reviewed Original ResearchConceptsReversible acute renal failureAcute renal failureBlood urea nitrogenNephrotic syndromeRenal failureDiabetic nephropathyDiabetic patientsRenal parametersRenal conditionsAcute oliguric renal failureEnd-stage renal diseaseType 1 diabetic patientsDiscontinuation of dialysisOliguric renal failureEarly diabetic nephropathyUrinary protein excretionMinimal change diseasePatient's renal conditionDiuretic therapyOvert proteinuriaRenal insufficiencyRenal functionSerum creatinineRenal biopsyRenal disease
1997
Influence of steroid withdrawal on proteinuria in renal allograft recipients
Ghandour FZ, Knauss TC, Mulligan DC, Schulak JA, Hricik DE. Influence of steroid withdrawal on proteinuria in renal allograft recipients. Clinical Transplantation 1997, 11: 395-398. PMID: 9361929, DOI: 10.1111/j.1399-0012.1997.tb00840.x.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnalysis of VarianceAnti-Inflammatory AgentsAzathioprineChi-Square DistributionChronic DiseaseCreatinineCyclosporineFemaleFollow-Up StudiesGlucocorticoidsGraft RejectionHumansImmunosuppressive AgentsKidney TransplantationLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrednisoneProteinuriaRecurrenceTransplantation, HomologousConceptsSteroid withdrawalUrinary protein excretionAllograft rejectionProtein excretionPrimary renal transplant recipientsAcute allograft rejectionRenal allograft recipientsRenal transplant recipientsChronic allograft rejectionSpot urine specimensAcute rejectionAllograft recipientsSteroid therapyTransplant recipientsClinical variablesUrine creatinineUrine specimensPatientsProteinuriaWithdrawalExcretionRecipientsRejectionCreatinineTransplantationUsefulness of Subnormal Midwall Fractional Shortening in Predicting Left Ventricular Exercise Dysfunction in Asymptomatic Patients With Systemic Hypertension
Schussheim A, Devereux R, de Simone G, Borer J, Herrold E, Laragh J. Usefulness of Subnormal Midwall Fractional Shortening in Predicting Left Ventricular Exercise Dysfunction in Asymptomatic Patients With Systemic Hypertension. The American Journal Of Cardiology 1997, 79: 1070-1074. PMID: 9114766, DOI: 10.1016/s0002-9149(97)00049-0.Peer-Reviewed Original ResearchConceptsMidwall fractional shorteningAsymptomatic hypertensive patientsLV ejection fractionFractional shorteningBlood pressureHypertensive patientsEjection fractionHigher mean diastolic blood pressureExtracardiac target organ damageHigher urinary protein excretionLower midwall fractional shorteningMean diastolic blood pressureLV functional reserveSerum creatinine levelsTarget organ damageUrinary protein excretionDiastolic blood pressureSystolic blood pressureHigher LV massBody mass indexIdentification of patientsExercise dysfunctionAsymptomatic patientsSystemic hypertensionCreatinine levels
1994
The benefit of early treatment with immunosuppressive agents in lupus nephritis.
Esdaile J, Joseph L, MacKenzie T, Kashgarian M, Hayslett J. The benefit of early treatment with immunosuppressive agents in lupus nephritis. The Journal Of Rheumatology 1994, 21: 2046-51. PMID: 7869308.Peer-Reviewed Original ResearchConceptsHour urinary protein excretionUrinary protein excretionLead-time biasRenal biopsyLupus nephritisRenal insufficiencyRenal involvementSerum creatinineProtein excretionImmunosuppressive agentsEarly treatmentHigh-dose prednisoneLupus renal involvementSubsequent renal insufficiencyTime biasFirst renal biopsySelection biasDose prednisoneTubulointerstitial indexRenal diseaseLongterm prognosisImmunosuppressive drugsEffect of durationBiopsySignificant association
1993
Urinary Protein Markers in Pesticide Applicators During a Chlorinated Hydrocarbon Exposure
Osterloh J, Feldman B. Urinary Protein Markers in Pesticide Applicators During a Chlorinated Hydrocarbon Exposure. Environmental Research 1993, 63: 171-181. PMID: 8243412, DOI: 10.1006/enrs.1993.1138.Peer-Reviewed Original ResearchConceptsRetinol-binding proteinProtein excretionRenal protein excretionUrine collection intervalsUrinary protein excretionUrinary protein markersN-acetylglucosaminidase (NAGCreatinine-corrected concentrationsLow concentrations of albuminExposure to DCPPesticide applicationAfternoon working shiftsRenal proteinsN-acetylglucosaminidaseConcentrations of albuminUrine samplesExcretionSignificant increaseProtein markersMinimal changesThe pathogenesis and prognosis of lupus nephritis: Information from repeat renal biopsy
Esdaile J, Joseph L, MacKenzie T, Kashgarian M, Hayslett J. The pathogenesis and prognosis of lupus nephritis: Information from repeat renal biopsy. Seminars In Arthritis And Rheumatism 1993, 23: 135-148. PMID: 8266110, DOI: 10.1016/s0049-0172(05)80019-8.Peer-Reviewed Original ResearchConceptsSecond biopsySubendothelial depositsLupus nephritisRenal biopsySubepithelial depositsDiffuse proliferative nephritisHealth activity indexRepeat renal biopsyActivity index scoreSerum creatinine levelsUrinary protein excretionImmune complex depositionLong-term outcomesPathogenesis of lupusChronicity indexTubulointerstitial indexRenal impairmentRenal insufficiencyCreatinine levelsInception cohortRenal functionProtein excretionComplex depositionMesangial hypercellularityMembranous pattern
1982
Mesangial disposal of glomerular immune deposits in acute malarial glomerulonephritis of rats.
Sterzel R, Ehrich J, Lucia H, Thomson D, Kashgarian M. Mesangial disposal of glomerular immune deposits in acute malarial glomerulonephritis of rats. Laboratory Investigation 1982, 46: 209-14. PMID: 7038293.Peer-Reviewed Original ResearchConceptsGlomerular immune depositsImmune depositsElectron-dense depositsDay 10Day 20Young Sprague-Dawley ratsRenal functional damageUrinary protein excretionInfiltration of monocytesGlomerular cell countSprague-Dawley ratsEsterase-positive monocytesGlomerular basement membraneAcute malariaProtein excretionGlomerular injuryMesangial distributionSerum urea valuesDay 100Granular depositionImmune complexesFunctional damageNormal rangeMesangial matrixCell count
1972
CLINICOPATHOLOGICAL CORRELATIONS OF PRIMARY HÆMATURIA
Hendler E, Kashgarian M, Hayslett J. CLINICOPATHOLOGICAL CORRELATIONS OF PRIMARY HÆMATURIA. The Lancet 1972, 299: 458-463. PMID: 4109816, DOI: 10.1016/s0140-6736(72)90121-3.Peer-Reviewed Original ResearchConceptsRenal diseaseProliferative glomerulonephritisPathological lesionsMild proliferative glomerulonephritisUrinary tract lesionsUrinary protein excretionGroup of patientsTypes of glomerulonephritisSevere proliferative glomerulonephritisType of lesionIntercurrent infectionRenal functionRenal biopsyProtein excretionPrimary lesionClinicopathological correlationDistribution of ageCorrect diagnosisPatientsGlomerulonephritisLesionsYoung adultsDiseaseHæmorrhageUseful index
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