2023
Primary hyperparathyroidism in patients with multiple endocrine neoplasia type 1: Impact of genotype and surgical approach on long-term postoperative outcomes
Shariq O, Abrantes V, Lu L, Tebben P, Foster T, Dy B, Lyden M, Young W, McKenzie T. Primary hyperparathyroidism in patients with multiple endocrine neoplasia type 1: Impact of genotype and surgical approach on long-term postoperative outcomes. Surgery 2023, 175: 8-16. PMID: 37891063, DOI: 10.1016/j.surg.2023.05.044.Peer-Reviewed Original ResearchConceptsMedian disease-free survivalDisease-free survivalPrimary hyperparathyroidismSurgical approachTruncated exon 2Total parathyroidectomyPostoperative outcomesExon 2Aggressive pNETsShorter median disease-free survivalHigh risk of recurrenceLong-term postoperative outcomesIncidence of postoperative hypoparathyroidismMultiple endocrine neoplasia type 1Incidence of permanent hypoparathyroidismPancreatic neuroendocrine tumorsAnalyzed baseline characteristicsRisk of recurrenceYounger median ageGermline pathogenic variantsHypoparathyroidism rateMEN1 genotypeMEN1 variantsPermanent hypoparathyroidismNeuroendocrine tumors
1985
New applications of total parathyroidectomy and autotransplantation: Use in proximal renal tubular dysfunction
Kinder B, Rasmussen H. New applications of total parathyroidectomy and autotransplantation: Use in proximal renal tubular dysfunction. World Journal Of Surgery 1985, 9: 156-164. PMID: 3838609, DOI: 10.1007/bf01656271.Peer-Reviewed Original ResearchConceptsTotal parathyroidectomyMetabolic bone diseaseBone diseaseProximal renal tubular dysfunctionGraft-dependent hypercalcemiaSevere bone diseaseVitamin D intoxicationTreatment of hyperparathyroidismCases of recurrentRenal tubular dysfunctionNew clinical settingsParathyroid massPersistent hyperparathyroidismRecurrent diseaseSecondary hyperparathyroidismPolyendocrine syndromeRenal osteodystrophySubtotal resectionFurther recurrenceParathyroid hyperplasiaTubular dysfunctionLocal anesthesiaEffective treatmentGraft tissueHigh incidence
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