2024
Progressive alterations of resting-state hypothalamic dysconnectivity in schizophrenia
Li X, Zeng J, Liu N, Yang C, Tao B, Sun H, Gong Q, Zhang W, Li C, Lui S. Progressive alterations of resting-state hypothalamic dysconnectivity in schizophrenia. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2024, 135: 111127. PMID: 39181307, DOI: 10.1016/j.pnpbp.2024.111127.Peer-Reviewed Original ResearchHypothalamic functional connectivityBilateral anterior cingulate cortexAnterior cingulate cortexFunctional connectivityFES patientsCingulate cortexFC decreaseRight thalamusChronically treated schizophrenia patientsHealthy controlsSeed-based functional connectivityFirst-episode patientsPathogenesis of schizophreniaNature of schizophreniaAge-related declineAntipsychotic treatmentAntipsychotic medicationRight caudateLeft putamenIllness durationAnalysis of covarianceSchizophreniaDiagnostic groupsHC groupHypothalamus dysfunctionSerum S100B protein and white matter changes in schizophrenia before and after medication
Shi H, Zhang Y, Yang Y, Zhang H, Li W, Zhong Z, Lv L. Serum S100B protein and white matter changes in schizophrenia before and after medication. Brain Research Bulletin 2024, 210: 110927. PMID: 38485004, DOI: 10.1016/j.brainresbull.2024.110927.Peer-Reviewed Original ResearchDecreased FA valuesSchizophrenia patientsFA valuesRight thalamusLeft inferior occipital gyrusPANSS positive scorePANSS positive scoresEffects of quetiapineLeft postcentral cortexLeft parietal cortexInferior occipital gyrusRight temporal cortexHealthy controlsWhite matterAtypical antipsychoticsPANSS scoresQuetiapine treatmentInvestigated WMOccipital gyrusRight cerebellumTemporal cortexParietal cortexWM microstructureBrain regionsSchizophrenia
2023
Auditory oddball hypoactivation in schizophrenia
Nakahara S, Male A, Turner J, Calhoun V, Lim K, Mueller B, Bustillo J, O'Leary D, Voyvodic J, Belger A, Preda A, Mathalon D, Ford J, Guffanti G, Macciardi F, Potkin S, Van Erp T. Auditory oddball hypoactivation in schizophrenia. Psychiatry Research Neuroimaging 2023, 335: 111710. PMID: 37690161, DOI: 10.1016/j.pscychresns.2023.111710.Peer-Reviewed Original ResearchConceptsSchizophrenia polygenic risk scoresFunctional magnetic resonance imagingPolygenic risk scoresCognitive performanceOddball targetsAssociated with cognitive performanceRight supramarginal cortexCognitive domain performanceBrain imaging studiesAuditory oddball taskPrecuneus activationSchizophrenia individualsFrontal poleSchizophreniaOddball taskBrain activityRight thalamusHippocampal cortexRegional activityHypoactivationSample 2Sample 1PrecuneusHealthy volunteersCross-sectional data sets
2022
Shared and distinct neural activity during anticipation and outcome of win and loss: A meta-analysis of the monetary incentive delay task
Chen Y, Chaudhary S, Li C. Shared and distinct neural activity during anticipation and outcome of win and loss: A meta-analysis of the monetary incentive delay task. NeuroImage 2022, 264: 119764. PMID: 36427755, PMCID: PMC9837714, DOI: 10.1016/j.neuroimage.2022.119764.Peer-Reviewed Original ResearchConceptsSupplementary motor areaMonetary incentive delay taskMedial orbitofrontal cortexBilateral anterior insulaLoss outcomesAnterior insulaLoss anticipationIncentive delay taskBilateral striatumPrecentral gyrusCingulate cortexBilateral medial orbitofrontal cortexDorsal anterior cingulate cortexRight occipital cortexDelay taskAnterior cingulate cortexPosterior cingulate cortexNeural correlatesActivation likelihood estimationRight thalamusMotor areaOccipital cortexRegional activityDistinct neural activityStriatum
2021
The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population
Miró-Padilla A, Adrián-Ventura J, Costumero V, Palomar-García M, Villar-Rodríguez E, Marin-Marin L, Aguirre N, Bueichekú E. The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population. Brain Structure And Function 2021, 226: 1871-1878. PMID: 34014400, DOI: 10.1007/s00429-021-02297-6.Peer-Reviewed Original ResearchConceptsAdhesio interthalamicaAssociated with lower GM volumeInferior frontal gyrusAI brainAnterior temporal cortexMRI scanning sessionsWhole-brain gray matterLower GM volumeGray matterGroup comparison analysisMidline brain structuresHealthy human adultsFrontal gyrusNeuroanatomical profileNeuroanatomical markersGM volumeTemporal cortexPremotor cortexBrain processesBrain structuresRight thalamusVolumetric differencesScanning sessionNeuroscience researchAnatomical profile
2015
A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder
Talati A, Pantazatos SP, Hirsch J, Schneier F. A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder. Psychiatry Research 2015, 231: 279-285. PMID: 25659476, PMCID: PMC4363180, DOI: 10.1016/j.pscychresns.2015.01.008.Peer-Reviewed Original ResearchConceptsParoxetine treatmentSignificant gray matter reductionsGray matter volume changesAnxiety disordersNeuro-anatomical changesGray matter reductionsSocial anxiety disorderClinical responseLiebowitz Social Anxiety ScaleSymptom improvementRight thalamusVBM8 toolboxLeft thalamusSuccessful treatmentWeek 8Bilateral caudateControl groupGray matterDSM-IVSymptom severityLongitudinal changesPilot study
2011
An Initial Study of Neural Responses to Monetary Incentives as Related to Treatment Outcome in Cocaine Dependence
Jia Z, Worhunsky PD, Carroll KM, Rounsaville BJ, Stevens MC, Pearlson GD, Potenza MN. An Initial Study of Neural Responses to Monetary Incentives as Related to Treatment Outcome in Cocaine Dependence. Biological Psychiatry 2011, 70: 553-560. PMID: 21704307, PMCID: PMC3162064, DOI: 10.1016/j.biopsych.2011.05.008.Peer-Reviewed Original ResearchConceptsRight ventral striatumVentral striatumCocaine dependenceRight insulaMonetary incentive delay taskRight caudateReward-based decisionIncentive delay taskTreatment retentionFunctional magnetic resonanceCD participantsMedial frontal gyrusRight thalamusUrine toxicologyTreatment outcomesReward anticipationReward processingDelay taskTask performanceFrontal gyrusGreater activationNeural responsesRewarding outcomesRight subcallosal gyrusMonetary rewards
2001
Regional Cerebral Blood Flow Abnormalities in Early-Onset Obsessive-Compulsive Disorder: An Exploratory SPECT Study
BUSATTO G, BUCHPIGUEL C, ZAMIGNANI D, GARRIDO G, GLABUS M, ROSARIO-CAMPOS M, CASTRO C, MAIA A, ROCHA E, MCGUIRE P, MIGUEL E. Regional Cerebral Blood Flow Abnormalities in Early-Onset Obsessive-Compulsive Disorder: An Exploratory SPECT Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2001, 40: 347-354. PMID: 11288777, DOI: 10.1097/00004583-200103000-00015.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderLate-onset subjectsOCD subjectsRegional cerebral blood flow (rCBF) single-photon emissionCerebral blood flow single photon emissionRegional cerebral blood flow abnormalitiesCerebral blood flow abnormalitiesObsessive-compulsive symptomsPathophysiology of OCDBlood flow abnormalitiesEarly-onset casesOnset obsessive-compulsive disorderFrontal-subcortical circuitsAge of onsetEarly-onset subjectsAnterior cingulate cortexPrefrontal cortex relativeSingle photon emissionStatistical parametric mappingRCBF differencesRight thalamusHealthy controlsFlow abnormalitiesClinical dataCortex relative
1998
Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease
Soufer R, Bremner J, Arrighi J, Cohen I, Zaret B, Burg M, Goldman-Rakic P. Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 6454-6459. PMID: 9600987, PMCID: PMC27794, DOI: 10.1073/pnas.95.11.6454.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseVisual association cortexSuperior frontal gyrusRight visual association cortexCAD patientsHealthy subjectsPositron emission tomographyMental stressAssociation cortexFrontal gyrusArtery diseaseMyocardial ischemiaAnterior cingulateCentral nervous system effectsCAD patient groupCerebral cortical responsePainless myocardial ischemiaNervous system effectsLeft parietal cortexInferior parietal lobuleMiddle temporal gyrusPatient groupSerial subtraction taskRight thalamusInferior frontal gyrus
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