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INFORMATION FOR

    Axon Degeneration

    Organizations

    Principal Investigators

    Axon Degeneration

    Degeneration — the same five axons, distal to the injury: beading, then myelin ovoids, then granular debris and a macrophage clearing it.

    Description

    Introduction

    Mitochondrial defects are tightly linked to axon degeneration, yet the underlying cellular mechanisms remain poorly understood. In Caenorhabditis elegans, PVQ axons that lack mitochondria degenerate spontaneously with age.

    Overview

    Themes

    Methods

    Results

    Collaborators

    Leadership

    • Marc Hammarlund, PhD

      Principal Investigator
      Yale School of Medicine

      Professor of Genetics and of Neuroscience