2024
Uncertainty in tuberculosis clinical decision-making: An umbrella review with systematic methods and thematic analysis
Basile F, Sweeney S, Singh M, Bijker E, Cohen T, Menzies N, Vassall A, Indravudh P. Uncertainty in tuberculosis clinical decision-making: An umbrella review with systematic methods and thematic analysis. PLOS Global Public Health 2024, 4: e0003429. PMID: 39042611, PMCID: PMC11265660, DOI: 10.1371/journal.pgph.0003429.Peer-Reviewed Original ResearchUmbrella reviewClinical decision-makingHealthcare system levelQualitative evidence synthesisBarriers to treatmentScarcity of healthcare resourcesTuberculosis knowledgeClinicians' attitudesCommon barriersResource-limited settingsHealth careHealthcare settingsClinical encountersEvidence synthesisInfluence clinical decisionsThematic analysisHealthcare resourcesDiagnostic test characteristicsStudy designSystematic reviewMeta-analysesNegative test resultsMulti-level modelProvidersDecision-making
2021
Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: a systematic review
Khundi M, Carpenter JR, Nliwasa M, Cohen T, Corbett EL, MacPherson P. Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: a systematic review. BMJ Open 2021, 11: e044715. PMID: 34257091, PMCID: PMC8278879, DOI: 10.1136/bmjopen-2020-044715.Peer-Reviewed Original ResearchConceptsSystematic reviewCommunity public health interventionsGlobal elimination targetsCommunity-based screeningControl of HIVMass drug administrationPublic health interventionsData extraction toolIndoor residual sprayingEvidence of effectWeb of ScienceCochrane DatabaseElimination targetsCommunity screeningInclusion criteriaDrug AdministrationHIVComplex interventionsHealth interventionsInfectious diseasesTuberculosisIntensive interventionIntervention impactMalaria studiesResidual sprayingIncidence and prevalence of tuberculosis in incarcerated populations: a systematic review and meta-analysis
Cords O, Martinez L, Warren JL, O’Marr J, Walter KS, Cohen T, Zheng J, Ko AI, Croda J, Andrews JR. Incidence and prevalence of tuberculosis in incarcerated populations: a systematic review and meta-analysis. The Lancet Public Health 2021, 6: e300-e308. PMID: 33765455, PMCID: PMC8168455, DOI: 10.1016/s2468-2667(21)00025-6.Peer-Reviewed Original ResearchConceptsPrevalence of tuberculosisIncidence of tuberculosisM tuberculosis infectionIncidence rate ratiosTuberculosis infectionGeneral populationSystematic reviewSouth-East Asia RegionIncarcerated populationsPopulation-level incidenceMycobacterium tuberculosis infectionRate ratioTuberculosis Control ProgrammeLILACS electronic databasesWHO Eastern Mediterranean RegionWHO South-East Asia RegionWeb of KnowledgeCohort studyUS National InstitutesSubgroup analysisPooled estimatesHigh riskElectronic databasesPreventive interventionsTuberculosisReporting practices for genomic epidemiology of tuberculosis: a systematic review of the literature using STROME-ID guidelines as a benchmark
Cheng B, Behr MA, Howden BP, Cohen T, Lee RS. Reporting practices for genomic epidemiology of tuberculosis: a systematic review of the literature using STROME-ID guidelines as a benchmark. The Lancet Microbe 2021, 2: e115-e129. PMID: 33842904, PMCID: PMC8034592, DOI: 10.1016/s2666-5247(20)30201-9.Peer-Reviewed Original ResearchConceptsGenomic epidemiology studiesStudy qualityProportion of criteriaEpidemiology studiesSystematic reviewInfectious Diseases guidelinesMean proportionNon-human studiesQuasi-Poisson regressionDisease guidelinesEmbase ClassicInfectious disease epidemiologyConference abstractsPrimary searchStudy characteristicsTuberculosisMolecular epidemiologyInitial searchSenior authorSearch termsTyping of strainsSample sizeEpidemiologyGenomic epidemiologyFull text
2020
The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis
Martinez L, Cords O, Horsburgh C, Andrews J, Consortium P, Acuna-Villaorduna C, Ahuja S, Altet N, Augusto O, Baliashvili D, Basu S, Becerra M, Bonnet M, Boom W, Borgdorff M, Boulahbal F, Carvalho A, Cayla J, Chakhaia T, Chan P, Cohen T, Croda J, Datta S, del Corral H, Denholm J, Dietze R, Dobler C, Donkor S, Egere U, Ellner J, Espinal M, Evans C, Fang C, Fielding K, Fox G, García L, García-Basteiro A, Geis S, Graham S, Grandjean L, Hannoun D, Hatherill M, Hauri A, Hesseling A, Hill P, Huang L, Huerga H, Hussain R, Jarlsberg L, Jones-López E, Kato S, Kato-Maeda M, Kampmann B, Kirchner H, Kritski A, Lange C, Lee C, Lee L, Lee M, Lemos A, Lienhardt C, Ling D, Liu Q, Lo N, Long R, Lopez-Varela E, Lu P, Magee M, Malone L, Mandalakas A, Martinson N, Mazahir R, Murray M, Netto E, Otero L, Parsonnet J, Reingold A, Schaaf H, Seddon J, Sharma S, Singh J, Singh S, Sloot R, Sotgiu G, Stein C, Iqbal N, Triasih R, Trieu L, van der Loeff M, Van der Stuyft P, van Schalkwyk C, Vashishtha R, Verhagen L, Villalba J, Wang J, Whalen C, Yoshiyama T, Zar H, Zellweger J, Zhu L. The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis. The Lancet 2020, 395: 973-984. PMID: 32199484, PMCID: PMC7289654, DOI: 10.1016/s0140-6736(20)30166-5.Peer-Reviewed Original ResearchConceptsYears of agePreventive therapyIncident tuberculosisTuberculosis infectionHazard ratioTuberculosis casesMixed-effects Poisson regression modelsSystematic reviewFinal analysisClose exposureIncident tuberculosis casesRisk of tuberculosisDevelopment of tuberculosisEMBASE electronic databasesIndividual participant dataPositive resultsPoisson regression modelsWeb of ScienceMixed-effects logistic modelBCG vaccinationCohort studyBaseline visitPrevalent tuberculosisContact investigationProspective study
2018
Spatially targeted screening to reduce tuberculosis transmission in high-incidence settings
Cudahy PGT, Andrews JR, Bilinski A, Dowdy DW, Mathema B, Menzies NA, Salomon JA, Shrestha S, Cohen T. Spatially targeted screening to reduce tuberculosis transmission in high-incidence settings. The Lancet Infectious Diseases 2018, 19: e89-e95. PMID: 30554997, PMCID: PMC6401264, DOI: 10.1016/s1473-3099(18)30443-2.Peer-Reviewed Original ResearchConceptsTuberculosis incidenceLow tuberculosis incidence settingsActive case-finding strategyHigh tuberculosis (TB) incidence countriesCase-finding strategyTuberculosis control strategiesHigh-incidence settingsInfectious causesIncidence settingsIncidence countriesTuberculosis transmissionTreatment outcomesActive screeningOnward transmissionSystematic reviewInfectious individualsInfectious periodTuberculosisIncidenceDeathCauseProximal causeHIVMixed resultsMortalityProgression from latent infection to active disease in dynamic tuberculosis transmission models: a systematic review of the validity of modelling assumptions
Menzies NA, Wolf E, Connors D, Bellerose M, Sbarra AN, Cohen T, Hill AN, Yaesoubi R, Galer K, White PJ, Abubakar I, Salomon JA. Progression from latent infection to active disease in dynamic tuberculosis transmission models: a systematic review of the validity of modelling assumptions. The Lancet Infectious Diseases 2018, 18: e228-e238. PMID: 29653698, PMCID: PMC6070419, DOI: 10.1016/s1473-3099(18)30134-8.Peer-Reviewed Original ResearchConceptsTuberculosis transmission modelActive diseaseCumulative incidenceRisk factorsSystematic reviewNatural historyFeatures of epidemiologyDisease natural historyIndividual risk factorsTuberculosis natural historyEarliest available dateWeb of ScienceAnnual incidenceCochrane LibraryTuberculosis incidenceInclusion criteriaFuture tuberculosisLatent infectionInitial infectionIncidenceSubstantial proportionPopulation groupsAvailable dateInfectionDiseaseThe impact of digital health technologies on tuberculosis treatment: a systematic review
Ngwatu B, Nsengiyumva N, Oxlade O, Mappin-Kasirer B, Nguyen N, Jaramillo E, Falzon D, Schwartzman K, Abubakar I, Alipanah N, Bastos M, Boccia D, Chin D, Cohen T, Davis J, Denkinger C, Falzon D, Fielding K, Fox G, Free C, Garfein R, Hayward A, Jaramillo E, Lester R, Lewis J, Mappin-Kasirer B, Marx F, Menzies D, Migliori G, Nahid P, Ngwatu B, Nsengiyumva N, Nguyen N, Oxlade O, Schwartzman K, Siddiqi K, Story A, Thomas B, Trajman A, Yassin M. The impact of digital health technologies on tuberculosis treatment: a systematic review. European Respiratory Journal 2018, 51: 1701596. PMID: 29326332, PMCID: PMC5764088, DOI: 10.1183/13993003.01596-2017.Peer-Reviewed Original ResearchConceptsVideo-observed therapyMedication monitorsStandard careObservational studyTreatment completion ratesTB treatment adherenceProbability of cureTreatment of personsPerson DOTActive tuberculosisTB careClinical outcomesTreatment adherenceTuberculosis treatmentPatient outcomesTreatment completionControl groupTreatment dosesSystematic reviewDigital health technologiesShort message serviceEffect estimatesTuberculosisDigital interventionsCare
2016
Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis
Kunkel A, Abel zur Wiesch P, Nathavitharana RR, Marx FM, Jenkins HE, Cohen T. Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis. BMC Infectious Diseases 2016, 16: 282. PMID: 27296716, PMCID: PMC4906576, DOI: 10.1186/s12879-016-1617-9.Peer-Reviewed Original ResearchConceptsPercentage of childrenSmear positivityPooled percentageInverse variance heterogeneity modelPediatric TB casesSmear-positive TBNational TB ProgrammeBurden of TBGlobal Health databasesSputum smear microscopyActive TBAdult tuberculosisPositive TBTB casesTB programsAdult casesPROSPERO databaseSputum smearInclusion criteriaSmear microscopyHealth databasesSystematic reviewAdultsChildrenTuberculosis
2014
The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis
Odone A, Amadasi S, White RG, Cohen T, Grant AD, Houben RM. The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis. PLOS ONE 2014, 9: e112017. PMID: 25391135, PMCID: PMC4229142, DOI: 10.1371/journal.pone.0112017.Peer-Reviewed Original ResearchConceptsHIV-positive peopleAntiretroviral therapyTB treatmentTuberculosis treatmentSystematic reviewHIV-positive TB casesCoverage of ARTRisk of deathMain outcome measuresOutcomes of interestTB casesDual epidemicsTB therapyRelative riskOutcome measuresPooled estimatesStudy populationProportion of individualsFatality ratioPositive peopleMeta-AnalysisART statusClinical settingManual searchMortalityIncidence of multidrug-resistant tuberculosis disease in children: systematic review and global estimates
Jenkins HE, Tolman AW, Yuen CM, Parr JB, Keshavjee S, Pérez-Vélez CM, Pagano M, Becerra MC, Cohen T. Incidence of multidrug-resistant tuberculosis disease in children: systematic review and global estimates. The Lancet 2014, 383: 1572-1579. PMID: 24671080, PMCID: PMC4094366, DOI: 10.1016/s0140-6736(14)60195-1.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisMultidrug-resistant tuberculosis diseaseTreatment-naive adultsMultidrug-resistant diseaseTuberculosis diseaseTuberculosis incidenceGlobal incidenceSystematic reviewCases of tuberculosisHarvard Medical SchoolGlobal tuberculosis incidenceGlobal annual incidenceTuberculosis riskAnnual incidencePatient groupUS National InstitutesWomen's HospitalInclusion criteriaInternal medicineNew diagnostic instrumentDisease riskTuberculosisIncidenceDiseaseHealth equity
2013
Isoniazid-resistant Tuberculosis in Children
Yuen CM, Tolman AW, Cohen T, Parr JB, Keshavjee S, Becerra MC. Isoniazid-resistant Tuberculosis in Children. The Pediatric Infectious Disease Journal 2013, 32: e217-e226. PMID: 23348808, PMCID: PMC3709006, DOI: 10.1097/inf.0b013e3182865409.Peer-Reviewed Original ResearchConceptsIsoniazid-resistant tuberculosisLatent tuberculosis infectionTuberculosis diseaseTuberculosis infectionIsoniazid resistancePediatric tuberculosis patientsTreatment of childrenIsoniazid-resistant strainsReports of childrenEffective regimensTuberculosis patientsTuberculosis treatmentAppropriate treatmentInclusion criteriaMedian proportionSystematic reviewRifampin resistanceDiseaseTuberculosisRegimensChildrenTreatmentInfectionIsoniazidHigher proportion